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Catalog	name	Description	price
R-R-2406	Niclosamide-13C6 CAS No.1325808-64-7	Niclosamide-13C6/CAS No.1325808-64-7 is the 13C6 labeled Niclosamide. Niclosamide (BAY2353) is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Niclosamide (BAY2353) inhibits STAT3 with IC50 of 0.25 μM in HeLa cells and inhibits DNA replication in a cell-free assay.	price>
R-C-707	Biotin NaYF4:Yb,Er(980 excitation, green light)	Biotin modified upconversion nanoparticles(980 excitation,green light),The emission wavelength is 540/650 nm±15 nm,the surface ligand is biotin,the particle size is 20-30 nm under electron microscope,and the solvent is water.	price>
R-R-2407	ML115 CAS No.912798-42-6	ML115/CAS No.912798-42-6 is a molecular probe of the signal transducer and activator of transcription (STAT3). ML115 is a STAT3 agonist.	price>
R-C-708	Biotin NaYF4:Yb,Tm(980 excitation, blue light)	Biotin modified upconversion nanoparticles (980 excitation,blue light),The emission wavelength is 365/450 /470 nm±15 nm,the surface ligand is biotin,the particle size is 20-30 nm under electron microscope,and the solvent is water.	price>
R-R-2408	Bruceantinol CAS No.53729-52-5	Bruceantinol/CAS No.53729-52-5, a quassinoid isolated from Brucea javanica, inhibits pepper mottle virus in pepper. Bruceantinol is a STAT3 inhibitor demonstrating potent antitumor activity in in vitro and in vivo human colorectal cancer (CRC) models. Bruceantinol strongly inhibits STAT3 DNA-binding ability (IC50=2.4 pM), blocks the constitutive and IL-6-induced STAT3 activation, and suppresses transcription of MCL-1, PTTG1, survivin and c-Myc.	price>
R-C-709	Biotin NaYF4:Yb,Er@NaYF4(980 excitation, green light)	Biotin modified core-shell upconversion nanoparticles(980 excitation,green light),The emission wavelength is 540/650 nm±15 nm,the surface ligand is biotin, the particle size is 30-40 nm under electron microscope,and the solvent is water.	price>
R-R-2409	Salviolone CAS No.119400-86-1	Salviolone/CAS No.119400-86-1 is a natural diterpenoid derivative that can against melanoma cells. Salviolone exhibits a pleiotropic effect against melanoma by hampering cell cycle progression, STAT3 signaling, and malignant phenotype of A375 melanoma cells.	price>
R-C-710	Biotin NaYF4:Yb,Tm@NaYF4(980 excitation, blue light)	Biotin modified core-shell upconversion nanoparticles(980 excitation,blue light),The emission wavelength is 365/450/470 nm±15 nm,the surface ligand is biotin,the particle size is 30-40 nm under electron microscope,and the solvent is water.	price>
R-R-2410	APTSTAT3-9R	APTSTAT3-9R, a specific STAT3-binding peptide, inhibits STAT3 activation and downstream signaling by specifically blocking STAT3 phosphorylation. APTSTAT3-9R exerts antiproliferative effects and antitumor activity.	price>
R-C-711	Biotin NaYF4,Yb,Er@NaYF4,Yb,Nd(808 excited, green light)	Biotin modified core-shell upconversion nanoparticles (808 excited,green light),The emission wavelength is 540/650 nm±15 nm,the surface ligand is biotin, the particle size is 30-40 nm under electron microscope, and the solvent is water.	price>
R-R-2411	MM-206 CAS No.1809581-87-0	MM-206/CAS No.1809581-87-0, a STAT3 activity inhibitor, potently inhibits the STAT3 SH2 domain-phosphopeptide interaction with IC50 of 1.2 μM. MM-206 demonstrates dose-dependent induction of apoptosis in acute myeloid leukemia (AML) cell lines.	price>
R-C-712	Biotin NaYF4,Yb,Tm@NaYF4,Yb,Nd(808 excited, blue light)	Biotin modified core-shell upconversion nanoparticles(808 excited,blue light),The emission wavelength is 365/450/470 nm±15 nm,the surface ligand is biotin,the particle size is 30-40 nm under electron microscope,and the solvent is water.	price>
R-R-2412	STAT3-IN-7 CAS No.1313019-65-6	STAT3-IN-7/1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea/CAS No.1313019-65-6 is a Sorafenib analogue and potently inhibits the phosphorylation of STAT3. STAT3-IN-7 induces cell apoptosis through SHP-1 dependent STAT3 inactivation. STAT3-IN-7 does not inhibit kinase activity and has anticancer effects.	price>
R-C-713	SB525334 cas:356559-20-1	SB525334 is a selective inhibitor of transforming growth factor-β receptor I (ALK5,TGF-βRI)(IC50=14.3 nM).Inhibits TGF-β1-induced smad2/3 nuclear localization and TGF-βRI-induced mRNA expression in kidney cells.	price>
R-R-2413	Stafia-1-dipivaloyloxymethyl ester CAS No.2582755-72-2	Stafia-1-dipivaloyloxymethyl ester (compound 27, 0-200 μM)/CAS No.2582755-72-2 decreases pSTAT5a expression significantly, and has no obvious inhibition on pSTAT5b.	price>
R-C-714	UNC-669 cas:1314241-44-5	UNC669 is a small-molecule antagonist of methyl-lysine(KMe)reader protein with selectivity for L3MBTL1 and L3MBTL3(IC50 of 4.2μM and 3.1μM respectively).	price>
R-R-2414	Eupalinolide K CAS No.108657-10-9	Eupalinolide K/CAS No.108657-10-9, a sesquiterpene lactones compound from Eupatorium lindleyanum, is a STAT3 inhibitor. Eupalinolide K is a Michael reaction acceptor (MRA) .	price>
R-C-715	Birinapant cas:1260251-31-7	Birinapant,also known as TL32711,is a synthetic small molecule and peptido mimetic of second mitochondrial-derived activator of caspases(SMAC) and inhibitor of IAP(Inhibitor of Apoptosis Protein)family proteins,with potential antineoplastic activity.	price>
R-R-2415	W1131 TFA	W1131 TFA is a potent STAT3 inhibitor that induces ferroptosis. W1131 inhibits cancer progression in subcutaneous xenograft, organoid, and PDX models of gastric cancer. W1131 effectively alleviates cancer cell chemoresistance to 5-FU (HY-90006). W1131 regulates the cell cycle, DNA damage response, and oxidative phosphorylation, including the IL6-JAK-STAT3 pathway and the ferroptosis pathway.	price>
R-C-716	MK2206 cas:1032350-13-2	MK-2206 dihydrochloride(MK-2206 (2HCl))is an orally active allosteric AKT inhibitor with IC50s of 5 nM,12 nM,and 65 nM for AKT1,AKT2, and AKT3,respectively.MK-2206 dihydrochloride induces autophagy.	price>

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