Home > Keywords > 
Catalog name Description price
R-C-692 Mesoporous silica coating NaYF4:Yb,Tm@NaYF4 (980 excited, blue light) Mesoporous silica coated core-shell upconversion nanoparticles(980 excitation, blue light)with hydroxyl groups as surface ligands,and the particle size is 50±15nm under electron microscope. price>
R-R-2392 Garcinone C CAS No.76996-27-5 Garcinone C/CAS No.76996-27-5, a xanthone derivative, is a natural compound extracted from Garcinia oblongifolia that is used as an anti-inflammatory, astringency and granulation-promoting medicine, and has potential cytotoxic effects on certain cancers. Garcinone C stimulates the expression levels of ATR and 4E-BP1, while efficiently inhibiting the expression levels of cyclin B1, cyclin D1, cyclin E2, cdc2, Stat3 and CDK7. Garcinone C significantly inhibits cell viability of the human Nasopharyngeal carcinoma (NPC) cell lines CNE1, CNE2, HK1 and HONE1 in a time‑ and dose‑dependent manner. price>
R-C-693 Mesoporous silica coating NaYF4,Yb,Er@NaYF4,Yb,Nd (808 excited, green) Mesoporous silica coated core-shell upconversion nanoparticles(980 excitation, blue light) have an emission wavelength of 540/650 nm±15 nm,a surface ligand of hydroxyl group,and a particle size of 50 ± 15 under electron microscope. The solvent is water. price>
R-R-2393 AK-2292 AK-2292 is a potent and selective STAT5 PROTAC degrader, with a DC50 of 0.10 μM. AK-2292 induces degradation of STAT5A/B proteins in vitro and in vivo. AK-2292 can induce tumor regression in acute myeloid leukemia and chronic myeloid leukemia xenograft mouse models. AK-2292 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. price>
R-C-694 Mesoporous silica coating NaYF4,Yb,Tm@NaYF4,Yb,Nd(808 excited, blue light) Mesoporous silica coated core-shell structure upconversion nanoparticles(980 excitation,blue light),emission wavelength is 365/450/470 nm ± 15 nm,surface ligand is hydroxyl,particle size under electron microscope is 50 ± 15.Solvent is water. price>
R-R-2394 IST5-002 CAS No.13484-66-7 IST5-002/CAS No.13484-66-7, a potent Stat5a/b inhibitor, selectively inhibits transcriptional activity of Stat5a/b (IC50s: 1.5 μM for Stat5a, 3.5 μM for Stat5b). IST5-002 inducs cell apoptotic and death of prostate cancer cells and chronic myeloid leukemia (CML) cells. IST5-002 can be used in the research of prostate cancer and chronic myeloid leukemia (CML). price>
R-C-695 Amine Functional Mesoporous silica coating NaYF4:Yb,Er(980 excitation, green light) Amidated mesoporous silica coated up conversion nanoparticles (980 excitation, green light),540/650nm±15 nm,surface ligand is NH2,particle size under electron microscope is 50±10.The solvent is water. price>
R-R-2395 Cirsilineol CAS No.41365-32-6 Cirsilineol/CAS No.41365-32-6, a natural flavone compound, selectively inhibits IFN-γ/STAT1/T-bet signaling in intestinal CD4+ T cells. Cirsilineol has potent immunosuppressive and anti-tumor properties. Cirsilineol significantly ameliorates trinitro-benzene sulfonic acid (TNBS)-induced T-cell-mediated experimental colitis in mice. price>
R-C-696 Amine Functional Mesoporous silica coating NaYF4:Yb,Tm(980 excitation, blue light) Amino mesoporous silica coated up conversion nanoparticles (980 excitation, blue light) have an emission wavelength of 365/450/470 nm±2 nm,a surface ligand of NH2,and a particle size of 50±10 under electron microscope.The solvent is water. price>
R-R-2396 HODHBt CAS No.28230-32-2 HODHBt (HOOBt)/CAS No.28230-32-2 inhibits STAT5-SUMO interaction by blocking SUMOylation of phosphorylated STAT5. HODHBt enhances the magnitude of IL-15 signaling and significantly increases the natural killer (NK) cell cytotoxicity phenotype and function and the generation of cytokine-induced memory-like (CIML) natural killer (NK) cells. HODHBt can be used for research of HIV-infection and cancer. price>
R-C-697 Amine Functional Mesoporous silica coating NaYF4:Yb,Er@NaYF4(980 excitation, green light) Amino mesoporous silica coated core-shell upconversion nanoparticles (980 excitation, green light) have an emission wavelength of 540/650 nm±2 nm,a surface ligand of NH2,and a particle size of 50±10nm under electron microscope. The solvent is water. price>
R-R-2397 Peramivir CAS No.330600-85-6 Peramivir/CAS No.330600-85-6 is an novel cyclopentane neuraminidase inhibitor of influenza virus. Peramivir has antiviral activity and anti-cytokines stom effects. Peramivir can be used for the research of COVID-19. price>
R-C-698 Amine Functional Mesoporous silica coating NaYF4:Yb,Tm@NaYF4(980 excited, blue light) The up conversion nanoparticles (980 excited,blue light) with aminated mesoporous silica core-shell structure emit at 365/450/470 nm ±15 nm,the surface ligand is NH2,and the particle size under electron microscope is 50±15.The solvent is water. price>
R-R-2398 Tetramethylcurcumin CAS No.52328-97-9 Tetramethylcurcumin (FLLL31)/CAS No.52328-97-9, derived from curcumin, specifically suppresses the phosphorylation of STAT3 by binding selectively to Janus kinase 2 and the STAT3 Src homology-2 domain. Tetramethylcurcumin exhibits anti-inflammatory and anti-cancer effects. price>
R-C-699 Amine Functional Mesoporous silica coating NaYF4,Yb,Er@NaYF4,Yb,Nd(808 excitation, green light) Amino mesoporous silica coated core-shell upconversion nanoparticles (808 excitation, green light) have an emission wavelength of 540/650 nm±15 nm,a surface ligand of NH2,and a particle size of 50 ± 15 under electron microscope. The solvent is water. price>
R-R-2399 (R)-Lisofylline CAS No.100324-81-0 (R)-Lisofylline ((R)-Lisophylline)/CAS No.100324-81-0 is a (R)-enantiomer of the metabolite of Pentoxifylline with anti-inflammatory properties. (R)-Lisofylline is a lysophosphatidic acid acyltransferase inhibitor with an IC50 of 0.6 µM and interrupts IL-12 signaling-mediated STAT4 activation. (R)-Lisofylline has the potential for type 1 diabetes, autoimmune disorders research. price>
R-C-700 Amine Functional Mesoporous silica coating NaYF4,Yb,Tm@NaYF4,Yb,Nd(808 excited, blue light) Amine Functional Mesoporous silica coating NaYF4,Yb,Tm@NaYF4,Yb,Nd(808 excited, blue light),The emission wavelength is 365/450/470nm15 nm,the surface ligand is NH2,the particle size under electron microscope is 50±15,and the solvent is water. price>
R-R-2400 STAT3-IN-15 STAT3-IN-15 is a potent and orally active STAT3 inhibitor against idiopathic pulmonary fibrosis (IPF). STAT3-IN-15 inhibits STAT3 phosphorylation. STAT3-IN-15 also inhibits the migration and deformation of epithelial cells induced by TGF-β1 and inhibit epithelial-mesenchymal transition (EMT). price>
R-C-701 Streptavidin modified NaYF4:Yb,Er(980 excitation, green light) Streptavidin modified upconversion nanoparticles (980 excitation, green light),The emission wavelength is 540/650 nm±15 nm,the surface ligand is streptavidin,the particle size is 20-30 nm under electron microscope,and the solvent is water. price>
R-R-2401 W1131 CAS No.2740522-79-4 W1131/CAS No.2740522-79-4 is a potent STAT3 inhibitor, triggering ferroptosis. W1131 suppresses cancer progression in gastric cancer cell subcutaneous xenograft model, organoids model, and PDX model. W1131 effectively alleviates chemical resistance of cancer cells to 5-FU (HY-90006). W1131 regulates cell cycle, DNA damage response, and oxidative phosphorylation, including IL6-JAK-STAT3 pathway and ferroptosis pathway. price>