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Catalog	name	Description	price
R-C-702	Streptavidin modified NaYF4:Yb,Tm (980 excitation, blue light)	Streptavidin modified upconversion nanoparticles(980 excitation,blue light), The emission wavelength is 365/450/470nm±15 nm,the surface ligand is streptavidin,and the particle size is 20-30nm under electron microscope.The solvent is water.	price>
R-R-2402	ENMD-1198 CAS No.864668-87-1	ENMD-1198 (IRC-110160)/CAS No.864668-87-1, an orally active microtubule destabilizing agent, is a 2-methoxyestradiol analogue with antiproliferative and antiangiogenic activity. ENMD-1198 is suitable for inhibiting HIF-1alpha and STAT3 in human HCC cells and leads to reduced tumor growth and vascularization.	price>
R-C-703	Streptavidin modified NaYF4:Yb,Er@NaYF4(980 excitation, green light)	Streptavidin modified core-shell upconversion nanoparticles(980 excitation,green light),The emission wavelength is 540/650 nm±15 nm,the surface ligand is streptavidin,the particle size is 30-40 nm under electron microscope,and the solvent is water.	price>
R-R-2403	C188 CAS No.823828-18-8	C188/CAS No.823828-18-8 is a STAT3 inhibitor that inhibits IL-6-stimulated STAT3 phosphorylation and nuclear translocation in HepG2 cells by targeting STAT3 SH2 domain peptide-binding pocket. C188, in particular, was highly active in inducing apoptosis of the breast cancer cell line MB-MDA-468 in vitro (EC50= 0.7 μM).	price>
R-C-704	Streptavidin modified NaYF4:Yb,Tm@NaYF4(980 excitation, blue light),core-shell	Streptavidin modified core-shell upconversion nanoparticles(980 excitation,blue light),The emission wavelength is 365/450/470 nm ±15 nm,the surface ligand is streptavidin,and the particle size is 30-40 nm under electron microscope.	price>
R-R-2404	CMD178 TFA	CMD178 TFA is a lead peptide that consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling and inhibits Treg cell development.	price>
R-C-705	Streptavidin modified NaYF4,Yb,Er@NaYF4,Yb,Nd(808 excited, green light),core-shell	Streptavidin modified core-shell upconversion nanoparticles (808 excited,green light),The emission wavelength is 540/650 nm±15 nm,the surface ligand is streptavidin,the particle size is 30-40 nm under electron microscope,and the solvent is water.	price>
R-R-2405	Stafib-2 CAS No.2097938-74-2	Stafib-2/CAS No.2097938-74-2 is a potent and selctive inhibitor of the transcription factor STAT5b, with an IC50 of 82 nM and 1.7 μM for STAT5b and STAT5a, respectively. Stafib-2 exhibits poor cell permeability.	price>
R-C-706	Streptavidin modified NaYF4,Yb,Tm@NaYF4,Yb,Nd(808 excited, blue light),core-shell	Streptavidin modified core-shell upconversion nanoparticles(808 excited,blue light). The emission wavelength is 365/450/470 nm±2 nm,the surface ligand is streptavidin,and the particle size is 30-40 nm under electron microscope.	price>
R-R-2406	Niclosamide-13C6 CAS No.1325808-64-7	Niclosamide-13C6/CAS No.1325808-64-7 is the 13C6 labeled Niclosamide. Niclosamide (BAY2353) is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Niclosamide (BAY2353) inhibits STAT3 with IC50 of 0.25 μM in HeLa cells and inhibits DNA replication in a cell-free assay.	price>
R-C-707	Biotin NaYF4:Yb,Er(980 excitation, green light)	Biotin modified upconversion nanoparticles(980 excitation,green light),The emission wavelength is 540/650 nm±15 nm,the surface ligand is biotin,the particle size is 20-30 nm under electron microscope,and the solvent is water.	price>
R-R-2407	ML115 CAS No.912798-42-6	ML115/CAS No.912798-42-6 is a molecular probe of the signal transducer and activator of transcription (STAT3). ML115 is a STAT3 agonist.	price>
R-C-708	Biotin NaYF4:Yb,Tm(980 excitation, blue light)	Biotin modified upconversion nanoparticles (980 excitation,blue light),The emission wavelength is 365/450 /470 nm±15 nm,the surface ligand is biotin,the particle size is 20-30 nm under electron microscope,and the solvent is water.	price>
R-R-2408	Bruceantinol CAS No.53729-52-5	Bruceantinol/CAS No.53729-52-5, a quassinoid isolated from Brucea javanica, inhibits pepper mottle virus in pepper. Bruceantinol is a STAT3 inhibitor demonstrating potent antitumor activity in in vitro and in vivo human colorectal cancer (CRC) models. Bruceantinol strongly inhibits STAT3 DNA-binding ability (IC50=2.4 pM), blocks the constitutive and IL-6-induced STAT3 activation, and suppresses transcription of MCL-1, PTTG1, survivin and c-Myc.	price>
R-C-709	Biotin NaYF4:Yb,Er@NaYF4(980 excitation, green light)	Biotin modified core-shell upconversion nanoparticles(980 excitation,green light),The emission wavelength is 540/650 nm±15 nm,the surface ligand is biotin, the particle size is 30-40 nm under electron microscope,and the solvent is water.	price>
R-R-2409	Salviolone CAS No.119400-86-1	Salviolone/CAS No.119400-86-1 is a natural diterpenoid derivative that can against melanoma cells. Salviolone exhibits a pleiotropic effect against melanoma by hampering cell cycle progression, STAT3 signaling, and malignant phenotype of A375 melanoma cells.	price>
R-C-710	Biotin NaYF4:Yb,Tm@NaYF4(980 excitation, blue light)	Biotin modified core-shell upconversion nanoparticles(980 excitation,blue light),The emission wavelength is 365/450/470 nm±15 nm,the surface ligand is biotin,the particle size is 30-40 nm under electron microscope,and the solvent is water.	price>
R-R-2410	APTSTAT3-9R	APTSTAT3-9R, a specific STAT3-binding peptide, inhibits STAT3 activation and downstream signaling by specifically blocking STAT3 phosphorylation. APTSTAT3-9R exerts antiproliferative effects and antitumor activity.	price>
R-C-711	Biotin NaYF4,Yb,Er@NaYF4,Yb,Nd(808 excited, green light)	Biotin modified core-shell upconversion nanoparticles (808 excited,green light),The emission wavelength is 540/650 nm±15 nm,the surface ligand is biotin, the particle size is 30-40 nm under electron microscope, and the solvent is water.	price>
R-R-2411	MM-206 CAS No.1809581-87-0	MM-206/CAS No.1809581-87-0, a STAT3 activity inhibitor, potently inhibits the STAT3 SH2 domain-phosphopeptide interaction with IC50 of 1.2 μM. MM-206 demonstrates dose-dependent induction of apoptosis in acute myeloid leukemia (AML) cell lines.	price>

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