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Catalog	name	Description	price
R-C-712	Biotin NaYF4,Yb,Tm@NaYF4,Yb,Nd(808 excited, blue light)	Biotin modified core-shell upconversion nanoparticles(808 excited,blue light),The emission wavelength is 365/450/470 nm±15 nm,the surface ligand is biotin,the particle size is 30-40 nm under electron microscope,and the solvent is water.	price>
R-R-2412	STAT3-IN-7 CAS No.1313019-65-6	STAT3-IN-7/1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea/CAS No.1313019-65-6 is a Sorafenib analogue and potently inhibits the phosphorylation of STAT3. STAT3-IN-7 induces cell apoptosis through SHP-1 dependent STAT3 inactivation. STAT3-IN-7 does not inhibit kinase activity and has anticancer effects.	price>
R-C-713	SB525334 cas:356559-20-1	SB525334 is a selective inhibitor of transforming growth factor-β receptor I (ALK5,TGF-βRI)(IC50=14.3 nM).Inhibits TGF-β1-induced smad2/3 nuclear localization and TGF-βRI-induced mRNA expression in kidney cells.	price>
R-R-2413	Stafia-1-dipivaloyloxymethyl ester CAS No.2582755-72-2	Stafia-1-dipivaloyloxymethyl ester (compound 27, 0-200 μM)/CAS No.2582755-72-2 decreases pSTAT5a expression significantly, and has no obvious inhibition on pSTAT5b.	price>
R-C-714	UNC-669 cas:1314241-44-5	UNC669 is a small-molecule antagonist of methyl-lysine(KMe)reader protein with selectivity for L3MBTL1 and L3MBTL3(IC50 of 4.2μM and 3.1μM respectively).	price>
R-R-2414	Eupalinolide K CAS No.108657-10-9	Eupalinolide K/CAS No.108657-10-9, a sesquiterpene lactones compound from Eupatorium lindleyanum, is a STAT3 inhibitor. Eupalinolide K is a Michael reaction acceptor (MRA) .	price>
R-C-715	Birinapant cas:1260251-31-7	Birinapant,also known as TL32711,is a synthetic small molecule and peptido mimetic of second mitochondrial-derived activator of caspases(SMAC) and inhibitor of IAP(Inhibitor of Apoptosis Protein)family proteins,with potential antineoplastic activity.	price>
R-R-2415	W1131 TFA	W1131 TFA is a potent STAT3 inhibitor that induces ferroptosis. W1131 inhibits cancer progression in subcutaneous xenograft, organoid, and PDX models of gastric cancer. W1131 effectively alleviates cancer cell chemoresistance to 5-FU (HY-90006). W1131 regulates the cell cycle, DNA damage response, and oxidative phosphorylation, including the IL6-JAK-STAT3 pathway and the ferroptosis pathway.	price>
R-C-716	MK2206 cas:1032350-13-2	MK-2206 dihydrochloride(MK-2206 (2HCl))is an orally active allosteric AKT inhibitor with IC50s of 5 nM,12 nM,and 65 nM for AKT1,AKT2, and AKT3,respectively.MK-2206 dihydrochloride induces autophagy.	price>
R-R-2416	Balsalazide sodium hydrate CAS No.150399-21-6	Balsalazide sodium hydrate/CAS No.150399-21-6 could suppress colitis-associated carcinogenesis through modulation of IL-6/STAT3 pathway.	price>
R-C-717	CYT387（Momelotinib） CAS:1056634-68-4	Momelotinib(CYT387)is an ATP-competitive inhibitor of JAK1/JAK2 with IC50a of 11 nM and 18 nM,respectively.CYT387 shows much less activity against JAK3.	price>
R-R-2417	STAT3-IN-17 CAS No.1245814-52-1	STAT3-IN-17/CAS No.1245814-52-1 is a moderate STAT3 inhibitor (IC50=0.7 μM; HEK-Blue IL-6), with antiproliferative activity in HeLa cells. STAT3-IN-17 has good pharmacokinetic characteristics. STAT3-IN-17 also inhibits pyruvate-ferredoxin oxidoreductase (PFOR), and inhibits Helicobacter pylori.	price>
R-C-718	AWD 131-138 CAS:188116-07-6	AWD 131-138(Imepitoin,ELB-138) is a centrally acting anti-epileptic which crosses the blood brain barrier and is used for the treatment of canine idiopathic epilepsy.AWD 131-138(Imepitoin)is an antiepileptic and antianxietic drug,AWD 131-138 can stimulate different recombinant isoforms of the rat GABA(A) receptor through the benzodiazepine binding site.	price>
R-R-2418	MNK8 CAS No.2055078-49-2	MNK8/CAS No.2055078-49-2 is a potent STAT3 (signal transducer and activator of transcription 3) inhibitor. MNK8 inhibits STAT3 activation and reduced its DNA binding ability. MNK8 shows good growth inhibition against hepatocellular carcinoma (HCC) cells. MNK8 induces apoptosis in HCC cells. MNK8 reduces prosurvival proteins expression and migration/invasion of HCC cells.	price>
R-C-719	BX795 CAS:702675-74-9	BX795 is a potent and selective inhibitor of PDK1,with an IC50 of 6 nM.BX795 is also a potent and relatively specific inhibitor of TBK1 and IKKɛ,with an IC50 of 6 and 41 nM,respectively.BX795 blocks phosphorylation of S6K1,Akt, PKCδ,and GSK3β,and has lower selectivity over PKA,PKC,c-Kit,GSK3β etc.BX795 modulates autophagy.	price>
R-R-2419	LY5 CAS No.1436382-03-4	LY5/CAS No.1436382-03-4 is a STAT3 inhibitor with an IC50 value of 0.5 μM. LY5 induces apoptosis and inhibits STAT3 phosphorylation. LY5 shows antitumor activity in vivo, it can be used for the research of cancer.	price>
R-C-720	CID-2011756 CAS:638156-11-3	CID 2011756 is an ATP competitive PKD inhibitor,with an IC50 of 3.2 µM for PKD1 in cell free assay,and also shows cellular pan-PKD inhibitory activity against PKD2 and PKD3 (IC50,0.6 and 0.7 µM,respectively).CID 2011756 also has antitumor activity.	price>
R-R-2420	Pimozide-d4 CAS No.1803193-57-8	Pimozide-d4/CAS No.1803193-57-8 is a deuterium labeled Pimozide. Pimozide is a dopamine receptor antagonist, with Kis of 1.4 nM, 2.5 nM and 588 nM for dopamine D2, D3 and D1 receptors, respectively, and also has affinity at α1-adrenoceptor, with a Ki of 39 nM; Pimozide also inhibits STAT3 and STAT5.	price>
R-C-721	Tenovin-3 CAS:1011301-27-1	Tenovin-3 is a small molecule activator of p53 transcriptional activity. It increases p53 activity in MCF-7 cells when used at a concentration of 10 µM.It also increases the level of K40-acetylated alpha-tubulin in H1299 cells and inhibits SIRT2 protein deacetylase activity.	price>
R-R-2421	Pimozide-d4-1	Pimozide-d4-1 is the deuterium labeled Pimozide. Pimozide is a dopamine receptor antagonist, with Kis of 1.4 nM, 2.5 nM and 588 nM for dopamine D2, D3 and D1 receptors, respectively, and also has affinity at α1-adrenoceptor, with a Ki of 39 nM; Pimozide also inhibits STAT3 and STAT5.	price>

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