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Catalog	name	Description	price
R-C-762	HS-173 cas:1276110-06-5	HS-173,a novel phosphatidylinositol 3-kinase(PI3K)inhibitor,has anti-tumor activity through promoting apoptosis and inhibiting angiogenesis.	price>
R-R-2462	BRD4 degrader AT1 CAS No.2098836-45-2	BRD4 degrader AT1/CAS No.2098836-45-2 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4 as a highly selective Brd4 degrader, with a Kd of 44 nM for Brd4BD2 in cells.	price>
R-C-763	DAPT (GSI-IX, LY-374973) cas:208255-80-5	DAPT(GSI-IX,LY-374973)is a novel γ-secretase inhibitor,which inhibits Aβ production with IC50 of 20 nM in HEK 293 cells.DAPT enhances the apoptosis of human tongue carcinoma cells and regulates autophagy.	price>
R-R-2463	BAY-299 CAS No.2080306-23-4	BAY-299/CAS No.2080306-23-4 is a very potent, dual inhibitor with IC50s of 67 nM for BRPF2 bromodomains (BD), 8 nM for TAF1 BD2, and 106 nM for TAF1L BD2.	price>
R-C-764	CZC54252 CAS:1191911-27-9	CZC54252 is a highly effective inhibitor of LRRK2.Its IC50 values for wild-type LRRK2 and mutant G2019S LRRK2 are 1.28 and 1.85 nm,respectively.	price>
R-R-2464	FKBP12 PROTAC dTAG-7 CAS No.2064175-32-0	FKBP12 PROTAC dTAG-7 (dTAG-7)/CAS No.2064175-32-0 is a heterobifunctional degrader. FKBP12 PROTAC dTAG-7 (dTAG-7) is a degrader of FKBP12F36V with expression of FKBP12F36V in-frame with a protein of interest. FKBP12 PROTAC dTAG-7 (dTAG-7) also is a selective degrader of BET bromodomain transcriptional co-activator BRD4 by bridging BET bromodomains to an E3 ubiquitin ligase CRBN.	price>
R-R-2465	Trotabresib CAS No.1706738-98-8	CC-90010 (compound 1)/CAS No.1706738-98-8 is a reversible and orally active BET inhibitor. CC-90010 is applied in the study for advanced solid tumors.	price>
R-R-2466	Biotinylated-JQ1 CAS No.1635437-52-3	Biotinylated-JQ1 (Biotin-JQ1)/CAS No.1635437-52-3 is a biotinylated derivative of JQ1 with high affinity for the bromodomain of BRD4. Biotinylated-JQ1 inhibits MM1.S multiple myeloma cells proliferation with the EC50 of 0.4 μM.	price>
R-R-2467	A1874 CAS No.2064292-12-0	A1874/CAS No.2064292-12-0 is a nutlin-based (MDM2 ligand) and BRD4-degrading PROTAC with a DC50 of 32 nM (induce BRD4 degradation in cells). Effective in inhibiting many cancer cell lines proliferation.	price>
R-R-2468	SGC-SMARCA-BRDVIII CAS No.1997319-84-2	SGC-SMARCA-BRDVIII/CAS No.1997319-84-2 is a potent and selective inhibitor of SMARCA2/4 and PB1(5), with Kds of 35 nM, 36 nM, and 13 nM, respectively. SGC-SMARCA-BRDVIII also inhibits PB1(2) and PB1(3), with Kds of 3.7 and 2.0 μM, respectively. SGC-SMARCA-BRDVIII can block adipogenesis of 3T3-L1 murine fibroblasts.	price>
R-R-2469	(+)-JQ1 PA CAS No.2115701-93-2	(+)-JQ1 PA/CAS No.2115701-93-2 is a derivative of the Bromodomain and extra-terminal (BET) inhibitor JQ1, with an IC50 of 10.4 nM. (+)-JQ1 PA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.	price>
R-R-2470	MI-463 CAS No.1628317-18-9	MI-463/CAS No.1628317-18-9 is a highly potent and orally bioavailable small molecule inhibitor of the menin-mLL interaction.	price>
R-R-2471	GSK 4027 CAS No.2079896-25-4	GSK 4027/CAS No.2079896-25-4 is a chemical probe for the PCAF/GCN5 bromodomain with an pIC50 of 7.4±0.11 for PCAF in a time-resolved fluorescence resonance energy transfer (TR-FRET) assay.	price>
R-C-772	PEO2200-b-PS10000	Poly(ethylene oxide)(PEO)has good hydrophilicity.A series of polymer dispersants can be prepared by block copolymerization,graft copolymerization or random copolymerization.By adjusting the proportion of oleophilic blocks,the adsorption stability between oleophilic blocks and particles can be enhanced,and the stability of suspension polymerization process can be effectively improved.	price>
R-R-2472	PROTAC BRD9 Degrader-1 CAS No.2097971-01-0	PROTAC BRD9 Degrader-1/CAS No.2097971-01-0 is a PROTAC BRD9 lead chemical degrader (IC50=13.5 nM), which can be used as a useful selective probe for studying the complex biology of BAF.	price>
R-C-773	PLL5k-g-PEG5k-MAL	Poly(L-lysine)-g-poly (ethylene glycol)-maleimide is produced by Ruixi bio. Poly(L-lysine)-g-poly (ethylene glycol)-maleimide is linked with poly(ethylene glycol),and the other end of poly(ethylene glycol)is modified with maleimide.We can provide more customized products.	price>
R-R-2473	BI-9564 CAS No.1883429-22-8	BI-9564/CAS No.1883429-22-8 is a potent, selective and cell-permeable BRD9/BRD7 bromodomains inhibitor, with IC50s of 75 nM and 3.4 μM and Kds of 14 nM and 239 nM, respectively. BI-9564 has an IC50 of > 100 μM for BET family.	price>
R-C-774	PEI coating Fe3O4 nanoparticles（50nm）	This product is Fe3O4 magnetic nanoparticles with particle size of 50nm,coated with Pei(polyethyleneimine)with different molecular weight,used for biomolecular coupling,immobilization,nanoprobe construction,etc.	price>
R-R-2474	I-CBP112 CAS No.1640282-31-0	I-CBP112/CAS No.1640282-31-0 is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor, that inhibits the CBP/p300 bromodomains, enhances acetylation by p300.	price>
R-C-775	25-35nm silica coated nano silver 60nm	This product is surface chemistry and coatings.Silver nanoparticles have a variety of anionic and cationic blocking ligands,from replaceable small molecules to polymer coatings.Standard(silanol)silica surfaces of silica shell silver nanospheres increase stability in a wide range of solvents.	price>

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