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Catalog	name	Description	price
R-R-2487	GSK620 CAS No.2088410-46-0	GSK620/CAS No.2088410-46-0 is a potent and orally active pan-BD2 inhibitor with excellent broad selectivity, developability and in vivo oral pharmacokinetics. GSK620 is highly selective for the BET-BD2 family of proteins, with >200-fold selectivity over all other bromodomains. GSK620 shows an anti-inflammatory phenotype in human whole blood.	price>
R-C-788	COOH-PEG1000-chitosan20000	Chitosan,also known as deacetylated chitin,is obtained by deacetylation of chitin, which widely exists in nature.Polyethylene glycol is an adduct of polyethylene oxide and water.	price>
R-R-2488	MI-538 CAS No.1857417-10-7	MI-538/CAS No.1857417-10-7 is an inhibitor of the interaction between menin and MLL fusion proteins with an IC50 of 21 nM.	price>
R-R-2489	CFT8634 CAS No.2704617-96-7	CFT8634/CAS No.2704617-96-7 is an oral activity degrader targeting BRD9 extracted from patent WO2021178920A1 compound 174. CFT8634 can be used for the research of synovial sarcoma and SMARCB1-deleted solid tumors.	price>
R-C-790	Inorganic composite nanomaterials（Ag Mn Au）	Nano materials refer to the macro materials formed by the accumulation of nanostructures in a certain way or dispersion in a certain matrix.Nano particles have special physical and chemical properties,which can be widely used in chemical industry,biology,medicine and other fields.	price>
R-R-2490	INCB-057643 CAS No.1820889-23-3	INCB-057643/CAS No.1820889-23-3 is a novel, orally bioavailable BET inhibitor.	price>
R-C-791	Oleic acid modified MnFe2O4 3NM	The MnFe2O4 nanocrystals modified by oleic acid are prepared by pyrolysis at high temperature.They can be stably dispersed in toluene or cyclohexane with a concentration of 5mg/ml,which is provided by Ruixi biological company.	price>
R-R-2491	ZL0454 CAS No.2229042-77-5	ZL0454/CAS No.2229042-77-5 is a potent and selective Bromodomain-containing protein 4 (BRD4) inhibitor with an IC50 of 49 and 32 nM for BD1 and BD2.	price>
R-C-792	MPC-PEG2000-PHB4000	2-methacryloyloxyethyl phosphorylcholine polymer has been widely used in tissue engineering,artificial organ,immobilized enzyme,blood purification,biosensor and daily chemicals due to its excellent blood compatibility and histocompatibility.	price>
R-R-2492	MI-136 CAS No.1628316-74-4	MI-136/CAS No.1628316-74-4 is an inhibitor of the menin-MLL protein-protein interaction (PPI), with an IC50 of 31 nM and a Kd of 23.6 nM. MI-136 shows to block AR signaling and has the potential for the study in castration-resistant tumors.	price>
R-C-793	G0-C14 CAS:1510653-27-6	G0-C14 is a cationic lipid-like compound alkyl-modified polyamidoamine (PAMAM) dendrimer.The particles are composed of three parts:outer peg surface,PLGA/G0-C14 layer,which play two roles:as a polymer matrix loaded with non-polar drugs,protecting and promoting siRNA molecules to stay in NP core and control drug release,and an aqueous inner core containing siRNA.	price>
R-R-2493	SIM1 CAS No.2719051-84-8	SIM1/CAS No.2719051-84-8 is a potent von Hippel-Lindau (VHL)-based trivalent PROTAC capable of degradation for all BET family members, with preference for BRD2 degradation (IC50=1.1 nM; Kd=186 nM). SIM1 shows sustained anti-cancer activity.	price>
R-C-794	PLL4300-PEG2000-modified Gold Nanoparticles（5nm）	Gold nanoparticles:they have good chemical inertness.Gold is one of the first metals found in history.Gold nanoparticles are also widely studied in Inorganic Chemistry and nanomaterials.	price>
R-R-2494	dBRD9 CAS No.2170679-45-3	dBRD9/CAS No.2170679-45-3,a PROTAC, can selective degrades BRD9. dBRD9 improves the bromine domain binding profile and reduces the binding activity of the whole BET family.	price>
R-C-795	Paclitaxel	Paclitaxel can make tubulin and tubulin dimer of microtubule lose dynamic balance,induce and promote tubulin polymerization,microtubule assembly,prevent depolymerization,so as to stabilize microtubule,inhibit the mitosis of cancer cells and trigger apoptosis,and then effectively prevent the proliferation of cancer cells and play an anti-cancer role.	price>
R-R-2495	PROTAC CBP/P300 Degrader-1 CAS No.2484739-48-0	PROTAC CBP/P300 Degrader-1/CAS No.2484739-48-0 is a potent PROTAC CBP/P300 degrader. PROTAC CBP/P300 Degrader-1 potently inhibited cell viability of multiple cancer cell lines.	price>
R-C-796	DSPE-PEG2000-Alendronate sodium	Alendronate sodium tablets,a bone metabolism regulator,is an aminodiphosphonate with strong affinity for hydroxyapatite in bone.When the osteoclasts dissolve the crystals,the drug is released,which can inhibit the activity of osteoclasts and indirectly inhibit bone resorption through osteoblasts.It is characterized by strong anti bone resorption activity and no inhibition of bone mineralization.	price>
R-R-2496	FHD-609 CAS No.2676211-64-4	FHD-609/CAS No.2676211-64-4 is an inhibitor and a degrader of BRD9 (bromodomain-containing protein 9). FHD-609 targets to ncBAF, can be used for research of wide range of cancers that contain a mutation in a BAF complex subunit. FHD-609 in combination with Telomelysin or INO5401, may play a role in adrenocortical carcinoma (ACC) treatment.	price>
R-C-797	DSPE-PEG2000-ASP8	PEG and DSPE are connected by carbamate bond.There are two saturated acyl chains. The lipophilic end is DSPE and the hydrophilic end is peg.The connection between PEG and liposome is firm and the ability to protect liposome from damage is the strongest.Asp8,which is similar to the hydroxyapatite binding domain of osteopontin and osteocalcin,has been used as a bone targeting part for the exclusive delivery of drugs to bone.	price>
R-R-2497	I-BET762 carboxylic acid CAS No.1300019-38-8	I-BET762 carboxylic acid (Molibresib carboxylic acid)/CAS No.1300019-38-8 is an I-BET762-based warhead ligand for conjugation reactions of PROTAC targeting on BET. I-BET762 carboxylic acid (Molibresib carboxylic acid) is a BRD4 inhibitor with a pIC50 of 5.1.	price>

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