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Catalog	name	Description	price
R-R-2483	PF-CBP1 hydrochloride CAS No.2070014-93-4	PF-CBP1 hydrochloride/CAS No.2070014-93-4 is a highly selective inhibitor of the CREB binding protein bromodomain (CBP BRD). PF-CBP1 inhibits CREBBP and EP300 bromodomains with IC50 of 125 nM and 363 nM respectively. PF-CBP1 hydrochloride reduces LPS-induced inflammatory cytokines expression (IL-1β, IL-6 and IFN-β) in primary macrophages. PF-CBP1 hydrochloride also downregulates RGS4 expression cortical neurons and can be used for the research of neurological disorders.	price>
R-R-2484	BAY1238097 CAS No.1564268-08-1	BAY1238097/CAS No.1564268-08-1 is a potent and selective inhibitor of BET binding to histones and has strong anti-proliferative activity in different AML (acute myeloid leukemia) and MM (multiple myeloma) models through down-regulation of c-Myc levels and its downstream transcriptome (IC50 <100 nM).	price>
R-C-785	PBA-PEG1000-cRGD	1-Pyrenebutyric acid(PBA)is a conjugated polymer that has a large π system and a carboxylic group.It is majorly used in surface functionalization.It has a high fluorescence efficiency and stability that make it useful in optoelectronic applications.	price>
R-R-2485	(S)-JQ-35 CAS No.1349719-98-7	(S)-JQ-35 (TEN-010)/CAS No.1349719-98-7 is an inhibitor of the Bromodomain and Extra-Terminal (BET) family bromodomain-containing proteins with potential antineoplastic activity.	price>
R-C-786	Compound customization (Rhodamine fluorescence)	Rhodamine is a laser dye,which is used for biological dyeing.It is a fluorescent dye,catechol.Rhodamine B is mainly used for industrial dyeing,and it is fat soluble.Rhodamine B has strong fluorescence in solution,so it can be used as fluorescent staining agent in laboratory.	price>
R-R-2486	ACBI2 CAS No.2913161-19-8	ACBI2/CAS No.2913161-19-8 is a highly potent and orally active VHL PROTAC SMARCA2 degrader (EC50: 7 nM), which selectively degrades SMARCA2 with a DC50 value of 1 nM in RKO cells. ACBI2 can be used in the research of lung cancer.	price>
R-C-787	18：1DGS_NTA	1,2-dioleoyl-sn-glycero-3-[(n-(5-amino-1-carboxyphenyl)iminodiacetic acid) succenyl](nickel salt)is a customized product from Ruixi biotechCo.Ltd.	price>
R-R-2487	GSK620 CAS No.2088410-46-0	GSK620/CAS No.2088410-46-0 is a potent and orally active pan-BD2 inhibitor with excellent broad selectivity, developability and in vivo oral pharmacokinetics. GSK620 is highly selective for the BET-BD2 family of proteins, with >200-fold selectivity over all other bromodomains. GSK620 shows an anti-inflammatory phenotype in human whole blood.	price>
R-C-788	COOH-PEG1000-chitosan20000	Chitosan,also known as deacetylated chitin,is obtained by deacetylation of chitin, which widely exists in nature.Polyethylene glycol is an adduct of polyethylene oxide and water.	price>
R-R-2488	MI-538 CAS No.1857417-10-7	MI-538/CAS No.1857417-10-7 is an inhibitor of the interaction between menin and MLL fusion proteins with an IC50 of 21 nM.	price>
R-R-2489	CFT8634 CAS No.2704617-96-7	CFT8634/CAS No.2704617-96-7 is an oral activity degrader targeting BRD9 extracted from patent WO2021178920A1 compound 174. CFT8634 can be used for the research of synovial sarcoma and SMARCB1-deleted solid tumors.	price>
R-C-790	Inorganic composite nanomaterials（Ag Mn Au）	Nano materials refer to the macro materials formed by the accumulation of nanostructures in a certain way or dispersion in a certain matrix.Nano particles have special physical and chemical properties,which can be widely used in chemical industry,biology,medicine and other fields.	price>
R-R-2490	INCB-057643 CAS No.1820889-23-3	INCB-057643/CAS No.1820889-23-3 is a novel, orally bioavailable BET inhibitor.	price>
R-C-791	Oleic acid modified MnFe2O4 3NM	The MnFe2O4 nanocrystals modified by oleic acid are prepared by pyrolysis at high temperature.They can be stably dispersed in toluene or cyclohexane with a concentration of 5mg/ml,which is provided by Ruixi biological company.	price>
R-R-2491	ZL0454 CAS No.2229042-77-5	ZL0454/CAS No.2229042-77-5 is a potent and selective Bromodomain-containing protein 4 (BRD4) inhibitor with an IC50 of 49 and 32 nM for BD1 and BD2.	price>
R-C-792	MPC-PEG2000-PHB4000	2-methacryloyloxyethyl phosphorylcholine polymer has been widely used in tissue engineering,artificial organ,immobilized enzyme,blood purification,biosensor and daily chemicals due to its excellent blood compatibility and histocompatibility.	price>
R-R-2492	MI-136 CAS No.1628316-74-4	MI-136/CAS No.1628316-74-4 is an inhibitor of the menin-MLL protein-protein interaction (PPI), with an IC50 of 31 nM and a Kd of 23.6 nM. MI-136 shows to block AR signaling and has the potential for the study in castration-resistant tumors.	price>
R-C-793	G0-C14 CAS:1510653-27-6	G0-C14 is a cationic lipid-like compound alkyl-modified polyamidoamine (PAMAM) dendrimer.The particles are composed of three parts:outer peg surface,PLGA/G0-C14 layer,which play two roles:as a polymer matrix loaded with non-polar drugs,protecting and promoting siRNA molecules to stay in NP core and control drug release,and an aqueous inner core containing siRNA.	price>
R-R-2493	SIM1 CAS No.2719051-84-8	SIM1/CAS No.2719051-84-8 is a potent von Hippel-Lindau (VHL)-based trivalent PROTAC capable of degradation for all BET family members, with preference for BRD2 degradation (IC50=1.1 nM; Kd=186 nM). SIM1 shows sustained anti-cancer activity.	price>
R-C-794	PLL4300-PEG2000-modified Gold Nanoparticles（5nm）	Gold nanoparticles:they have good chemical inertness.Gold is one of the first metals found in history.Gold nanoparticles are also widely studied in Inorganic Chemistry and nanomaterials.	price>

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