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Catalog	name	Description	price
R-R-2559	PROTAC BRD4-binding moiety 1 CAS No.2101200-10-4	PROTAC BRD4-binding moiety 1/CAS No.2101200-10-4 is a ligand for BRD4. PROTAC BRD4-binding moiety 1 binds to cereblon ligand via a linker to form PROTAC to degrade BRD4 (HY-133136). PROTAC BRD4-binding moiety 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.	price>
R-C-860	Alexa Fluor 555	Probes with high fluorescence quantum yield and high photostability allow detection of low-abundance biological structures with great sensitivity. Invitrogen Alexa Fluor 555 dye molecules can be attached to proteins at high molar ratios without significant self-quenching,enabling brighter conjugates and more sensitive detection.We offer Alexa Fluor 555 dye conjugated to a variety of antibodies,peptides,proteins,tracers,and amplification substrates optimized for cellular labeling and detection.In addition,reactive dye forms and protein labeling kits are available to allow you to generate your own antibody conjugates or probes.	price>
R-R-2560	653-47 hydrochloride CAS No.1224567-46-7	653-47 hydrochloride/CAS No.1224567-46-7, a potentiator, significantly potentiates the cAMP-response element binding protein (CREB) inhibitory activity of 666-15. 653-47 hydrochloride is also a very weak CREB inhibitor with IC50 of 26.3 μM.	price>
R-C-861	DMSP	Osmolar dimethylsulfonylpropionate(DMSP)of algae is the main precursor of marine dimethyl sulfide(DMS).DMS is a volatile sulfur compound,which affects atmospheric chemistry and global climate.DMSP may play an important role in the microbial ecology and biogeochemistry of the marine surface.The sulfur in DMSP is effectively bound to bacterial proteins(mainly methionine),and DMSP seems to be the main source of sulfur in marine planktonic bacteria.	price>
R-R-2561	XX-650-23 CAS No.117739-40-9	XX-650-23/CAS No.117739-40-9 is a potent CREB inhibitor. XX-650-23inhibits CREB function through disruption of CBP-CREB interaction. XX-650-23 can be used for AML research.	price>
R-C-862	PPS-PEG	Amphiphilic block copolymers based on hydrophobic polysulfide(PPS)and hydrophilic polyether(PEG)have been used for solubilization and dispersion of single-walled carbon nanotubes(SWNTs).The high concentration aqueous dispersion was stable for several months.	price>
R-R-2562	PBRM1-BD2-IN-5 CAS No.2819989-61-0	PBRM1-BD2-IN-5/CAS No.2819989-61-0 is a potent PBRM1 Bromodomain inhibitor with Kd values of 1.5 μM and 3.9 μM for PBRM1-BD2 and PBRM1-BD5, respectively, and an IC50 value of 0.26 μM for PBRM1-BD2. PBRM1-BD2-IN-5 reduces the binding of full-length PBRM1 within the PBAF complex in cell lysates to acetylated histone peptide. PBRM1-BD2-IN-5 can be used to research anticancer.	price>
R-C-863	PPS-PEI	Polysulfides,any of a class of compounds,containing one or more clusters of sulfur that are connected by covalent bonds.Polyethyleneimine(PEI) had the best transfection effect.Polyethyleneimine(PEI)is an organic polymer with high charge density.Every two carbon atoms are separated,that is,the third atom is protonated amino nitrogen,which makes the polymer network function as an effective proton sponge at any pH value.	price>
R-R-2563	INCB054329 CAS No.1628607-64-6	INCB054329/CAS No.1628607-64-6 is a potent BET inhibitor.	price>
R-C-864	MPEG-CE6	CE6 is usually synthesized from pheophorbidic acid A.It is a good photosensitizer with similar biological activity to pheophorbidic acid a.CE6 is highly efficient in producing singlet oxygen because it is suitable for developing photodynamic therapy for tumors.CE6 is hydrophobic and easy to aggregate in solution.	price>
R-R-2564	PROTAC BRD4 Degrader-1 CAS No.2133360-00-4	PROTAC BRD4 Degrader-1/CAS No.2133360-00-4 is a PROTAC connected by ligands for Cereblon and BRD4 with an IC50 of 41.8 nM against BRD4 BD1. PROTAC BRD4 Degrader-1 can effectively degrade BRD4 protein and suppress c-Myc expression.	price>
R-C-865	PEI-PBLG	PEI(10kd)-PBLG can encapsulate plasmids to form nanocomposites with particle size of 100~120nm,which is suitable for mediating plasmids into cells.The results showed that the nanoparticle complex had low sensitivity to transfection buffer,and could transfect all experimental cell lines in the presence of 10% serum,especially HeLa,followed by COS-7,Vero-E6 and ECV304;the transfection rate of PEI-PBLG(10kd)/pEGFP complex was 45.02%,which was higher than that of PEI (10kd)/pEGFP(29.16%);The cytotoxicity of PEI(10kd)-PBLG was significantly lower than Pei(25kd),Pei(10kd)and Pei(25kd)-PBLG.Pei(10kd)-PBLG,a new cationic polymer,not only improves the efficiency of Pei mediated gene transfection,but also reduces its cytotoxicity and improves its biocompatibility.	price>
R-R-2565	XP-524 CAS No.2344825-52-9	XP-524/CAS No.2344825-52-9 is a potent BET and EP300 inhibitor. XP-524 shows great tumoricidal activity in vivo. XP-524 prevents KRAS-induced, neoplastic transformation in vivo and extends survival in two transgenic mouse models of aggressive PDAC. XP-524 also enhances the presentation of self-peptide and tumor recruitment of cytotoxic T lymphocytes. XP-524 has the potential for the research of pancreatic ductal adenocarcinoma (PDAC).	price>
R-C-866	ZIF-8 coated chondroitinase ABC	ABC enzyme can degrade chondroitin sulfate A,chondroitin sulfate B(dermatan sulfate)and chondroitin sulfate C.The enzyme acts on the β 1-4 glycosides between disaccharide repeats and cuts them off through the mechanism of β elimination.The degradation products are oligosaccharides,mainly unsaturated disaccharides.Chondroitin sulfate can be quantified by the determination of unsaturated disaccharide products.	price>
R-R-2566	BET bromodomain inhibitor 1 CAS No.2411226-02-1	BET bromodomain inhibitor 1/CAS No.2411226-02-1 is an orally active, selective bromodomain and extra-terminal (BET) bromodomain inhibitor with an IC50 of 2.6 nM for BRD4. BET bromodomain inhibitor 1 binds to BRD2(2), BRD3(2), BRD4(1), BRD4(2), and BRDT(2) with high affinities (Kd values of 1.3 nM, 1.0 nM, 3.0 nM, 1.6 nM, 2.1 nM, respectively). bromodomain inhibitor 1 has anti-cancer activity.	price>
R-C-867	4arm-PEG5K-TK-COOH	Keto mercaptan is a reactive group of ROS.Keto mercaptan polymers are widely used in inflammation and tumor.Inflammation and tumor have high levels of ROS, which can break keto mercaptan chemical bond and realize drug release. Polyethylene glycol(PEG)is a kind of high molecular polymer,which has no irritation,slightly bitter taste,good water solubility and good compatibility with many organic components.	price>
R-R-2567	GSK1379725A CAS No.1802251-00-8	GSK1379725A/CAS No.1802251-00-8 is a selective BPTF ligand with a Kd of 2.8 uM, showing no binding activity for Brd4.	price>
R-C-868	Gold nanorods coated with erythrocyte membrane&Rhodamine	Gold nanorods can be used as a drug delivery carrier.Drugs can be attached to the surface of gold nanorods by physical adsorption or chemical conjugation,and can maintain the activity of drugs until they are released.Gold nanoparticles can be completely coated by cell membrane,and the coated particles can also prevent macrophage phagocytosis.As a complete cell membrane coated particle,it can also modify functional groups on its surface for drug targeted delivery.	price>
R-R-2568	UMB298 CAS No.2266569-73-5	UMB298/CAS No.2266569-73-5 is a potent and selective CBP/P300 bromodomain inhibitor.	price>
R-C-869	N-acetyl-d-glucosamine(NAG)-PLGA10K-PEG2k LA:GA=50:50	N-acetylglucosamine(NAG)is the basic component of many important polysaccharides in biological cells,especially the exoskeleton of crustaceans.It is an important premise for the synthesis of bifidus factor and has many important physiological functions in the organism.It is mainly used in clinic to enhance the function of human immune system,inhibit the overgrowth of cancer cells or fibroblasts, inhibit and treat cancer and malignant tumor,etc.	price>

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