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| Catalog | name | Description | price |
|---|---|---|---|
| R-R-2569 | BRD4 Inhibitor-24 CAS No.309951-18-6 | BRD4 Inhibitor-24 (compound 3U)/CAS No.309951-18-6 is a potent BRD4 inhibitor, BRD4 Inhibitor-24 shows antitumor activity against MCF7 and K652 cells, with IC50 values of 33.7 and 45.9 μM, respectively (extracted from patent CN107721975A). | price> |
| R-C-870 | Oil soluble manganese dioxide nanoparticles(25nm) | The oil soluble manganese dioxide nanoparticles,with a diameter of about 25 nm, were dispersed in organic solvent(chloroform). | price> |
| R-R-2570 | SR-0813 CAS No.2597186-19-9 | SR-0813/CAS No.2597186-19-9 is a potent and selective ENL/AF9 YEATS domain inhibitor. SR-0813 has IC50 and EC50 values of 25 nM and 205 nM for ENL YEATS domain, respectively. SR-0813 has IC50 and EC50 values of 311 nM and 76 nM (CETSA) for AF9 YEATS domain, respectively. SR-0813 binds MAP3K19 with over 100-fold lower affinity (Kd=3.5 μM) than ENL YEATS (Kd=30 nM). SR-0813 can be used for the research of acute leukemia. | price> |
| R-C-871 | COOH-PEG2K-Ge11 | Peptide ge11 is a small molecule peptide obtained by phage peptide library screening technology,which is composed of 11 amino acids(yhwygytpqnvi).Ge11 can specifically bind to EGFR,and ge11 has no effect on cell growth.The results showed that the liposomes modified with ge11 had high targeting to EGFR. | price> |
| R-R-2571 | EML 425 CAS No.1675821-32-5 | EML425/CAS No.1675821-32-5 is a potent and selective CREB binding protein (CBP)/p300 inhibitor with IC50s of 2.9 and 1.1 μM, respectively. | price> |
| R-C-872 | Cy5.5 labeled cationic liposomes | Ruixibio can provide blank liposome,fluorescent labeled liposome,liposome encapsulated drug or small molecule,liposome encapsulated protein or nucleic acid,liposome encapsulated polypeptide,liposome encapsulated fluorescent dye ICG photosensitizer,liposome encapsulated inorganic nanoparticles,liposome encapsulated quantum dot up conversion,Mir contrast liposome,and more Our reagents are only used for scientific research products,not for human body. | price> |
| R-R-2572 | L-Moses dihydrochloride | L-Moses (L-45) dihydrochloride is the first potent, selective, and cell-active p300/CBP-associated factor (PCAF) bromodomain (Brd) inhibitor with a Kd of 126 nM. | price> |
| R-C-873 | T807-NH2 | T807 is an effective tau protein imaging agent.Ruixibio can provide some inhibitors,peptides,phospholipids,fluorescent dyes,etc.,as well as high-end special customized products. | price> |
| R-R-2573 | b-NF-JQ1 CAS No.2380000-55-3 | β-NF-JQ1/CAS No.2380000-55-3 is a PROTAC that recruits Aryl Hydrocarbon Receptor E3 ligase to target proteins. β-NF-JQ1 is directed against bromodomain-containing (BRD) proteins using β-NF as an AhR ligand, induces the interaction of AhR and BRD proteins, and displays effective anticancer activity that correlated with protein knockdown activity. | price> |
| R-C-874 | Silybin biotin | Silymarin is an antioxidant derived from a plant called milk thistle.Silymarin can stabilize the membrane of liver cells,maintain the integrity of liver cells, prevent the toxin from penetrating and damaging the liver,accelerate the synthesis of DNA (deoxyribonucleic acid)of liver cells,prevent liver cirrhosis, fatty liver,cholangitis,psoriasis and other diseases,and inhibit the growth and differentiation of liver cancer,prostate cancer,breast cancer and cervical cancer cells. | price> |
| R-R-2574 | GSK852 CAS No.2305842-30-0 | GSK852/CAS No.2305842-30-0 is a highly potent, second bromodomain (BD2)-selective, bromo and extra-terminal domain (BET) inhibitor (pIC50 = 7.9). | price> |
| R-C-875 | Custom adriamycin materials | Doxorubicin is also known as 14 hydroxy positive dingmycin 14 hydroxydaunorubicin,doxorubicin,adriamycin,adriamycin and hydroxyerythromycin are anthracycline antitumor antibiotics produced by Streptomyces peucetius subsp Caesius.They are cell cycle nonspecific drugs(CCNSA)and are sensitive to s and M phases.The hydrochloride is orange needle crystal. | price> |
| R-R-2575 | OARV-771 CAS No.2683008-37-7 | OARV-771/CAS No.2683008-37-7 is a VHL-based BET degrader (PROTAC) with improved cell permeability. OARV-771 shows DC50s of 6, 1, and 4 nM for Brd4, Brd2 and Brd3, respectively. | price> |
| R-C-876 | Oil soluble PbS quantum dots (1000 nm absorption) | The surface of oil soluble PbS quantum dots is coated with hydrophobic ligands, and the average quantum yield is 50%.The oil soluble PbS quantum dots should be kept away from direct sunlight,sealed in 4 degrees dark,and PL 800 nm-1600 nm. | price> |
| R-R-2576 | I-BET567 CAS No.1887237-54-8 | I-BET567/CAS No.1887237-54-8 is a potent and orally active inhibitor of pan-BET candidate with pIC50s of 6.9 and 7.2 for BRD4 BD1 and BD2, respectively. I-BET567 has been demonstrated efficacy in mouse models of oncology and inflammation. | price> |
| R-C-877 | BMS-1(HY19991) CAS:1675201-83-8 | BMS-1(PD-1/PD-L1 inhibitor1,PD1-PDL1-IN1)is a small-molecule inhibitor of PD-1/PD-L1 interaction with IC50 of 6 nM. | price> |
| R-R-2577 | Y06137 CAS No.2226534-49-0 | Y06137/CAS No.2226534-49-0 is a potent and selective BET inhibitor for treatment of castration-resistant prostate cancer (CRPC). Y06137 binds to the BRD4(1) bromodomain with a Kd of 81 nM. | price> |
| R-R-2578 | BET bromodomain inhibitor CAS No.1505453-59-7 | BET bromodomain inhibitor/CAS No.1505453-59-7 is a potent BET inhibitor extracted from patent WO/2015/153871A2, compound example 11. | price> |
| R-C-879 | poly(lactic-co-glycolic acid)-thioketal-amino acid | Ruixibio can provide poly(lactic-co-glycolic acid)-thioketal-amino acid.PLGA is a kind of degradable functional polymer organic compound,which is randomly polymerized by lactic acid and glycolic acid.It has good biocompatibility,non toxicity,encapsulation and film-forming properties.It can be used as drug delivery carrier and tissue engineering scaffold material. | price> |
| R-R-2579 | Thalidomide-NH-CBP/p300 ligand 2 CAS No.2484739-21-9 | Thalidomide-NH-CBP/p300 ligand 2 (P-007)/CAS No.2484739-21-9 is a PROTAC-based CBP and p300 degrader (extracted from patent WO2020173440). | price> |

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