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Catalog	name	Description	price
R-C-890	HSA-CY5	Human serum albumin (HSA)is the main plasma protein.It can bind with water,Ca (2 +),Na(+),K(+),fatty acids,hormones and drugs,and maintain the colloidal osmotic pressure of blood.Cy5 fluorescent dyes:dyes that emit fluorescence.Cy5 is very sensitive to its surrounding electronic environment,which can be used for enzyme detection.The conformational changes of attachment proteins can lead to positive or negative changes of fluorescence emission.Cyanine dye is a relatively old fluorescent dye,but it is the basis for other fluorescent dyes to improve their brightness,light resistance and quantum yield.	price>
R-R-2590	PROTAC BRD4 Degrader-11	PROTAC BRD4 Degrader-11 (compound 9a) is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. PROTAC BRD4 Degrader-11 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.23 nM and 0.38 nM, respectively.	price>
R-C-891	NH2-PEG5K-cRGDfK	Polyethylene glycol(PEG)is a kind of oligomer or polymer of ethylene oxide.The series of products are non-toxic,non irritating, slightly bitter in taste,with good water solubility and good compatibility with many organic components.	price>
R-R-2591	PROTAC BRD4 Degrader-12 CAS No.2417370-90-0	PROTAC BRD4 Degrader-12 (compound 9c)/CAS No.2417370-90-0 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. PROTAC BRD4 Degrader-12 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.39 nM and 0.24 nM, respectively.	price>
R-C-892	Aminated mesoporous silica coated silver nanoparticles（100NM ）	Porous silica has the characteristics of large specific surface area,good chemical stability,good biocompatibility and controllable pore size.Currently, the main synthetic methods of mesoporous silica include sol gel method, hydrothermal method and so on.Silver nanoparticles have been widely used as catalyst materials,antistatic materials,low-temperature superconducting materials and medical antibacterial materials because of their ultra-high specific surface area,surface activity,conductivity and antibacterial properties.	price>
R-R-2592	MS31 CAS No.2366264-12-0	MS31/CAS No.2366264-12-0 is a potent, highly affinity and selective fragment-like methyllysine reader protein spindlin 1 (SPIN1) inhibitor. MS31 potently inhibits the interactions between SPIN1 and H3K4me3 (IC50=77 nM, AlphaLISA; 243 nM, FP). MS31 selectively binds Tudor domain II of SPIN1 (Kd=91 nM). MS31 potently inhibits binding of trimethyllysine-containing peptides to SPIN1. MS31 is not toxic to nontumorigenic cells.	price>
R-C-893	NH2-PEG2000-Cy5	Amine-Polyethylene glycol-cy5 is linked to drug molecules,peptides,DNA,proteins and small molecules with NHS and COOH.	price>
R-R-2593	PROTAC BRD4 Degrader-9 CAS No.2417370-42-2	PROTAC BRD4 Degrader-9 (compound 8a)/CAS No.2417370-42-2 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. PROTAC BRD4 Degrader-9 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.86 nM and 7.6 nM, respectively.	price>
R-C-894	Triptolide-Biotin	Tripterygium wilfordii is an effective proteasome inhibitor,which can induce cancer cell apoptosis by inhibiting proteasome activity.Biotin was well tolerated.	price>
R-R-2594	Menin-MLL inhibitor 19 CAS No.2360487-93-8	Menin-MLL inhibitor 19/CAS No.2360487-93-8, a potent exo-aza spiro inhibitor of menin-mll interaction, example A17, extracted from patent WO2019120209A1. Menin-MLL inhibitor 19 can be used for the reseaech of various diseases, such as cancer, myelodysplastic syndrome (MDS) and diabetes.	price>
R-C-895	Simultaneous modification of folic acid / azide by sialic acid	Sialic acid is a general term for a class of derivatives of neuraminic acid in which amino hydrogen or hydroxyl hydrogen is substituted.It also refers to N-acetylneuraminic acid,one of the most important members of such compounds. Sialic acid is widely distributed in animal tissues and a small amount in other organisms,mainly as a component of glycoprotein and ganglioside.	price>
R-R-2595	GSK973 CAS No.2138473-38-6	GSK973/CAS No.2138473-38-6 is a highly selective, orally bioavailable inhibitor of the BD2s (second bromodomains) of the BET family, with a pIC50 of 7.8 and a pKd of 8.7 for BRD4 BD2. GSK973 displays a 1600-fold selectivity for BRD4 BD2 over BRD4 BD1. GSK973 shows good potency against BRD2 BD2, BRD3 BD2, and BRDT BD2 (pIC50=7.4~7.8; pKd=8.3~8.5).	price>
R-C-896	cRGD-PAE1K-SS-PEG2K-b-PCL4K	Arg Gly ASP is composed of arginine,glycine and aspartic acid.RGD cell binding sequences have been identified in other extracellular matrix proteins,including fibronectin and laminin.A family of membrane proteins called integrins act as receptors for these cell adhesion molecules through RGD motifs.	price>
R-R-2596	PROTAC BET degrader-2 CAS No.2093388-33-9	PROTAC BET degrader-2/CAS No.2093388-33-9 is a PROTAC connected by ligands for Cereblon and BET with an IC50 value of 9.6 nM in cell growth inhibition in the RS4;11 cells and capable of achieving tumor regression.	price>
R-R-2597	TP-238 hydrochloride CAS No.2415263-05-5	TP-238 hydrochloride/CAS No.2415263-05-5 is a potent and selective dual CECR2/BPTF probe with IC50 values of 30 nM and 350 nM, respectively. TP-238 hydrochloride also inhibits BRD9 with a pIC50 of 5.9 and is less active against other 338 kinases.	price>
R-C-898	Cy5.5-PEG5000-hydrazide	Cy5.5 peg hydrazide is a kind of nano active near infrared fluorescent dye with terminal hydrazide group(-NH2).Hydrazide is a carbonyl reaction functional group,which can react with aldehyde or ketone groups to form a stable hydrazone bond.The reaction of hydrazide and carbonyl group makes cy5.5 dye combine with polysaccharide,glycosylated protein,antibody and enzyme.Cy5.5peg dye is a bright near-infrared fluorescent dye with excitation/emission wavelengths of 675nm/ 694nm.The peg crosslinker between cy5.5 and hydrazide group has better water solubility,lower steric hindrance and higher stability.	price>
R-R-2598	CBP/p300-IN-20	CBP/p300-IN-20 is a potent and selective p300/CBP inhibitor, with a pIC50 of 10.1 for p300. CBP/p300-IN-20 can be used for the research of cancer.	price>
R-C-899	Cy5.5-PEG1000	Cyanine dyes are one of the most commonly used fluorescent dyes in near-infrared (NIR)fluorescent dyes.Compared with conventional visible dyes,cyanine dyes have significant advantages.The molar absorptivity of cyanine dyes is the highest among the fluorescent dyes.The absorption of Cy5 hydrazide,cy5.5 alkyne and cy7 NHS ester is very low in the near-infrared region.They are the most stable long wavelength dyes with the highest fluorescence intensity.Women provides special cross-linking products of fat soluble cyanine dyes,water-soluble cyanine dyes and polyethylene glycol,PEG terminal links with various conventional groups and special groups,and accepts high difficulty product customization services.	price>
R-R-2599	Naringenin triacetate CAS No.3682-04-0	Naringenin triacetate/CAS No.3682-04-0 is a flavonoid isolated from plant, exhibits a good binding affinity with multiple crystal structures of first bromodomain BRD4 (BRD4 BD1).	price>
R-C-900	Cy5.5-PEG2000	Cyanine dyes are one of the most commonly used fluorescent dyes in near-infrared (NIR)fluorescent dyes.Compared with conventional visible dyes,cyanine dyes have significant advantages.The molar absorptivity of cyanine dyes is the highest among the fluorescent dyes.The absorption of Cy5 hydrazide, cy5.5 alkyne and cy7 NHS ester is very low in the near-infrared region.They are the most stable long wavelength dyes with the highest fluorescence intensity.Women provides special cross-linking products of fat soluble cyanine dyes,water-soluble cyanine dyes and polyethylene glycol,PEG terminal links with various conventional groups and special groups,and accepts high difficulty product customization services.	price>

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