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Catalog	name	Description	price
R-R-2600	Phoenixin-20 CAS No.1415039-77-8	Phoenixin-20 (PNX-20)/CAS No.1415039-77-8 is a bioactive peptide with hormone-like actions in vertebrates, and can stimulates hypothalamo-pituitary-gonadal hormones and regulate reproductive processes in mammals. Phoenixin-20 promotes neuronal mitochondrial biogenesis via CREB-PGC-1α pathway. Phoenixin-20 has anxiolytic effect.	price>
R-C-901	Cy5.5-PEG5000	Cyanine dyes are one of the most commonly used fluorescent dyes in near-infrared (NIR)fluorescent dyes.Compared with conventional visible dyes,cyanine dyes have significant advantages.The molar absorptivity of cyanine dyes is the highest among the fluorescent dyes.The absorption of Cy5 hydrazide, cy5.5 alkyne and cy7 NHS ester is very low in the near-infrared region.They are the most stable long wavelength dyes with the highest fluorescence intensity.Women provides special cross-linking products of fat soluble cyanine dyes,water-soluble cyanine dyes and polyethylene glycol,PEG terminal links with various conventional groups and special groups,and accepts high difficulty product customization services.	price>
R-R-2601	Luteolin 7-sulfate CAS No.56857-57-9	Luteolin 7-sulfate/CAS No.56857-57-9 is isolated from Phyllospadix iwatensis Makino, a marine plant. Luteolin 7-sulfate attenuates TYR gene expression through the intervention of a cAMP-responsive element binding protein (CREB)- and microphthalmia-associated transcription factor (MITF)-mediated signaling pathway, leading to the decreased melanin synthesis.	price>
R-C-902	Black phosphorus Nanocomposite	Black phosphorus(BP)is a kind of crystal with structure similar to graphene.It is an allotrope of phosphorus and can exist in nature stably.As a new type of two-dimensional nano material,black phosphorus nano sheet has attracted extensive attention in the field of biomedicine,such as disease treatment,drug carrier,clinical detection,due to its large specific surface area,good biocompatibility,excellent photothermal properties and so on.	price>
R-R-2602	IV-255	IV-255 is a selective small molecule inhibitor of the BRG1 bromodomain. IV-255 increases the extent of DNA damage induced by Temozolomide (HY-17364) and Bleomycin (HY-108345). IV-255 inhibits the invasiveness of GBM cells. IV-255 enhances Temozolomide-induced cell death and the apoptosis-inducing activity of Temozolomide.	price>
R-C-903	Plant carbon point customization	As a new kind of zero dimensional carbon based nano fluorescent materials, carbon dots have attracted much attention.Due to its simple preparation,low toxicity,biocompatibility,easy functionalization,photobleaching resistance and fluorescence tunability,carbon dots have shown great potential in the field of biology.	price>
R-R-2603	iBRD4-BD1 diTFA CAS No.2839318-20-4	iBRD4-BD1 diTFA/CAS No.2839318-20-4 is selective BRD4 bromodomain inhibitor. iBRD4-BD1 diTFA has inhibition activity for BRD4 bromodomain with an IC50 value of 12 nM. iBRD4-BD1 diTFA can be used for the research of inflammation and oncology.	price>
R-C-904	Fingolimod hydrochloride-biotin	Fingolimod Hydrochloride is the hydrochloride salt form of fingolimod,an orally available derivate of myriocin and sphingosine-1-phosphate receptor 1(S1PR1, S1P1)modulator,with potential anti-inflammatory and immunomodulating activities. Upon oral administration,fingolimod,as a structural analogue of sphingosine, selectively targets and binds to S1PR1 on lymphocytes and causes transient receptor activation followed by S1PR1 internalization and degradation.	price>
R-R-2604	ZEN-3219 CAS No.1952264-34-4	ZEN-3219/CAS No.1952264-34-4 is a BET inhibitor with IC50s of 0.48, 0.16 and 0.47 μM for BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2), respectively. ZEN-3219 can be used to form PROTACs to induce degradation of BRD4.	price>
R-C-905	FITC labeled 388 active substance	FITC fluorescein isothiocyanate is a commonly used method to label antibody. FITC is usually yellow,brown or brownish yellow powder or crystal with stable properties and can be stored for several years at low temperature.Under alkaline conditions,the carboamide bond of FITC can covalently bind with lysine amino group on antibody protein to form FITC protein conjugate,namely fluorescent antibody or fluorescent conjugate.	price>
R-R-2605	(+)-JQ-1-aldehyde CAS No.2634778-37-1	(+)-JQ-1-aldehyde/CAS No.2634778-37-1 is the aldehyde form of (+)-JQ1. (+)-JQ-1-aldehyde can be uesd as a precursor to synthesize PROTACs, which targets BET bromodomains.	price>
R-C-906	Polyphyllin I-cy3	Cy3 dye is a bright orange fluorescent dye,which can use 532 nm laser spectral line and display through TRITC(tetramethyl rhodamine)filter.In addition to immunocytochemical applications,Cy3 dye is usually used to label nucleic acids. Paris polyphylla saponin I is characterized by high sensitivity,strong specificity and good repeatability.Due to its stable reagent,easy preservation, simple operation and objective result judgment,it has been widely used in various fields of immunology.	price>
R-R-2606	OXFBD04 CAS No.2231747-03-6	OXFBD04/CAS No.2231747-03-6 is a potent and selective BRD4 inhibitor with an IC50 of 166 nM. OXFBD04 is a potent BET bromodomain ligand with additional modest affinity for the CREBBP bromodomain. OXFBD04 has anti-cancer activity.	price>
R-C-907	DSPE-PVGLIG-PEG2K	Sodium alginate was used as the matrix to modify the metalloproteinase sensitive peptide Pro-Va1l-Gly-Leu-Iso-Gly(PVGLIG),which promoted the maturation of dendritic cells in vitro,neither dissociated nor combined with sodium alginate chain,It shows low immunogenicity.	price>
R-R-2607	Menin-MLL inhibitor-22 CAS No.2851841-61-5	Menin-MLL inhibitor-22 (compound C20)/CAS No.2851841-61-5 is an orally active inhibitor of the interaction between menin and mixed lineage leukemia (MLL) (IC50=7 nM). Menin-MLL inhibitor-22 binds menin protein and inhibits cancer cell growth (MV4 cells, IC50=0.3 μM). Menin is a putative tumor suppressor associated with multiple endocrine neoplasia type 1 (MEN-1 syndrome).	price>
R-C-908	Stick shape Fe3O4（100nm）	Fe3O4 has stable material properties,good compatibility with organisms,high strength and magnetism.In the aspect of targeted drug carrier,magnetic targeted nano drug carrier can directly reach the lesions through the effect of external magnetic field after loading the components of drugs,which can reduce the side effects of drugs on other organs and tissues,and improve the efficacy and enhance the therapeutic effect.	price>
R-R-2608	PROTAC BRD4 Degrader-10 CAS No.2417370-49-9	PROTAC BRD4 Degrader-10 (compound 8b)/CAS No.2417370-49-9 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. PROTAC BRD4 Degrader-10 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 1.3 nM and 18 nM, respectively.	price>
R-C-909	Furan modified sodium alginate	Sodium alginate is a by-product of extracting iodine and mannitol from kelp or Sargassum.Its molecule is composed of β-D-mannuronic acid (m) and α-L-guluronic acid(g)by(1→4)bonds.It is a natural polysaccharide with the stability,solubility,viscosity and safety required for pharmaceutical excipients.	price>
R-R-2609	Bromodomain inhibitor-8 CAS No.1300031-70-2	Bromodomain inhibitor-8 (Intermediate 21)/CAS No.1300031-70-2 is a BET bromodomain inhibitor for treating autoimmune and inflammatory diseases.	price>
R-C-910	Fe3O4-PEG-CY5.5	Fe3O4 is a compound with the chemical formula Fe3O4.It exists in nature in the form of magnetite.Fe3O4 contains Fe2+and Fe3+ions,sometimes written as FeO.Fe2O3,Fe3O4 is most widely used as a black pigment.Cyanine 5.5 is widely used not only as a biomarker,but also as a derivatization reagent for some small molecules.Cyanine 5.5 is a common near-infrared fluorescent dye.	price>

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