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R-R-2610 UNC1021 CAS No.1322591-19-4 UNC1021/CAS No.1322591-19-4 is a selective L3MBTL3 inhibitor with an IC50 of 0.048 μM. price>
R-C-911 Oleic acid coated scintillators Scintillator is a kind of material that can emit light after absorbing high-energy particles or rays.It plays a very important role in the field of radiation detection.It is usually processed into crystal in application,which is called scintillation crystal.Rare earth nanocrystalline scintillators are characterized by easy size control,colorless transparency,good dispersion and excellent afterglow performance. price>
R-R-2611 PROTAC BRD9 Degrader-6 CAS No.2676211-62-2 PROTAC BRD9 Degrader-6/CAS No.2676211-62-2 is a potent degrader of BRD9 (IC50=0.13 nM), can be used for research of BAF complex-related disorders. price>
R-C-912 Chitosan coated gold nanoparticles Nanoparticles are solid colloidal particles with the size of 10~1000 nm,which can be used as drug delivery carriers.Nano drug delivery system is a new drug carrier produced by nano drug delivery technology.It has the characteristics of targeting,controlled release and surface modifiability.It can effectively pass through the mucosal surface and transport into the systemic circulation. Chitosan has excellent biocompatibility and bioadhesion as a new drug carrier. price>
R-R-2612 Halofuginone CAS No.55837-20-2 Halofuginone (RU-19110)/CAS No.55837-20-2, a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM. Halofuginone is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity. Halofuginone is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca2+ channels. Halofuginone has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects. price>
R-C-913 Galactose-VK19 Galactose(CH2OH(Choh)4cho)is a kind of monosaccharide,which can be found in dairy products or sugar beet.Galactose is a monosaccharide composed of six carbons and one aldehyde group,which is classified as aldose and hexose.It often exists in the form of d-galactoside in brain and nerve tissues,and is also an important component of some glycoproteins.The monosaccharide absorbed most quickly in the intestine is galactose. price>
R-R-2613 SRI-011381 hydrochloride CAS No.2070014-88-7 SRI-011381 hydrochloride/CAS No.2070014-88-7 is an orally active TGF-β signaling agonist, exhibits neuroprotective effects. price>
R-C-914 PPS50-PEG44-Rosmarinic acid Pps-peg poly(propylene sulfide)-polyethylene glycol copolymerization can form self-assembled amphiphilic substances.Keto mercaptan has also been successfully used in gene delivery.Amphiphilic block copolymers based on hydrophobic polysulfide(PPS)and hydrophilic polyether(PEG)have been used for solubilization and dispersion of single-walled carbon nanotubes(SWNTs).Rosmarinic acid(Rosa) is a kind of water-soluble natural phenolic acid isolated from rosemary,which is a natural antioxidant with strong antioxidant activity.Its antioxidant activity is stronger than vitamin E,caffeic acid,chlorogenic acid,folic acid and so on.It helps to prevent cell damage caused by free radicals,thus reducing cancer and animal mortality Risk of pulse hardening. price>
R-R-2614 Trabedersen sodium Trabedersen sodium is an antisense oligodeoxynucleotide that specifically inhibits TGF-β2 (TGF-beta/Smad). Trabedersen sodium can be used for the study of malignant brain tumors and other solid tumors overexpressing TGF-β2, such as those of the skin, pancreas and colon. price>
R-C-915 Albumin nanoparticles encapsulated ICG ICG nanoprobes were prepared by albumin self-assembly method with adjustable particle size,good stability,biocompatibility and tumor targeting. price>
R-R-2615 SRI-011381 CAS No.1629138-41-5 SRI-011381/CAS No.1629138-41-5 is an orally active TGF-β signaling agonist, exhibits neuroprotective effects. price>
R-C-916 QSY21-NHS The amine reactive quencher QSY 21 succinimidyl ester has a broad and intense absorption 661 nm maxima but no fluorescence making it useful as an acceptor in fluorescence resonance energy transfer FRET applications. price>
R-R-2616 Halofuginone hydrobromide CAS No.64924-67-0 Halofuginone (RU-19110) hydrobromid/CAS No.64924-67-0, a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM. Halofuginone hydrobromid is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity. Halofuginone hydrobromid is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca2+ channels. Halofuginone hydrobromid has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects. price>
R-C-917 Ce6-NHS Ce6-NHS is a chlorophyll derivative that is photosensitive and capable of producing singlet oxygen when activated with light (typically in the red to near-infrared spectrum).Ce6-NHS exhibits strong absorbance and fluorescence which can be utilized in imaging.It can generate reactive oxygen species (ROS) upon light activation, making it suitable for photodynamic therapy applications to target cancer cells. Used in PDT for the treatment of various cancers, as well as in imaging and diagnostic applications due to its fluorescence properties. N-hydroxysuccinimide (NHS) Ester/NHS esters are often used in bioconjugation to attach compounds (like Ce6) to proteins, peptides, or other biomolecules without causing significant steric hindrance or denaturation.NHS esters are widely used in biochemistry and biotechnology for labeling proteins and other biomolecules. price>
R-R-2617 Ponsegromab CAS No.2368950-15-4 Ponsegromab (PF 06946860)/CAS No.2368950-15-4 is a potent and selective humanized anti-GDF15 antibody inhibitor with anti-cachexia activity. Ponsegromab binds to GDF15 and prevents the binding of GDF15 to GFRAL, thereby blocking GDF15/GFRAL-mediated signaling. Ponsegromab can be used in the research of cancers. price>
R-C-918 PLA10K-PBA Conductive polymer composites(CPC)with different CB and PBA contents were prepared by using polylactic acid(PLA)as plasticizer and carbon black(CB)as conductive filler.FTIR analysis showed that there was interaction between PLA / PBA matrix and carbon black filler,and PBA could improve the interaction.The results of rheological properties show that carbon black can significantly improve the apparent viscosity and reduce the fluidity of the composites, while polyanilic acid has the opposite effect. price>
R-R-2618 EMT inhibitor-1 CAS No.1638526-21-2 EMT inhibitor-1/CAS No.1638526-21-2 is an inhibitor of of Hippo, TGF-β, and Wnt signaling pathways with antitumor activities. price>
R-C-919 Azithromycin limonamide tobramycin Azithromycin(azithromycin)is a semi synthetic 15 membered macrolide antibiotic, which is used to treat bacterial infection.The mechanism of action of azithromycin is the same as that of erythromycin and other drugs.It also produces antibacterial effect by inhibiting bacterial protein synthesis. Tobramycin is an aminoglycoside antibiotic.It is used for urinary tract infections caused by Staphylococcus and gram-negative bacilli,such as pyelonephritis,cystitis,epididymitis,pelvic inflammatory disease,prostatitis, etc.respiratory tract infections,such as pneumonia,acute or chronic bronchitis,etc.ophthalmic preparations are used for the treatment of local infections of external eyes and appendages caused by sensitive bacteria.The three components all have antibacterial effect. price>
R-R-2619 R-268712 CAS No.879487-87-3 R-268712/CAS No.879487-87-3 is an orally active and selective ALK-5 inhibitor, with an IC50 of 2.5 nM. R-268712 inhibits the phosphorylation of Smad3 in a dose-dependent manner with an IC50 of 10.4 nM. R-268712 suppresses glomerulonephritis as well as glomerulosclerosis by inhibiting TGF-β signaling, which can be used in studies of renal fibrosis and cancer. price>
R-C-920 Pyropheophorbide a cas:24533-72-0 Pyropheophorbide a is a natural catabolite of ethylene-induced chlorophyll a degradation.Extracts of C.paradoxa contain pyropheophorbide a and significantly inhibit the growth of cancer cells in vitro. price>