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Catalog	name	Description	price
R-R-2630	Butaprost CAS No.69685-22-9	Butaprost/CAS No.69685-22-9 is a selective prostaglandin E receptor (EP2) agonist with an EC50 of 33 nM and a Ki of 2.4 μM for murine EP2 receptor. Butaprost is less activity against murine EP1, EP3 and EP4 receptors. Butaprost attenuates fibrosis by hampering TGF-β/Smad2 signalling.	price>
R-C-931	TTQ-F-NH2 95%	Amino functionalized near-infrared two zone probe ttq-f-nh2,near-infrared two zone(nir-ii,1000-1700 nm)fluorescence imaging,is a new optical imaging technology,with the advantages of high imaging resolution,high tissue penetration depth and weak autofluorescence,which can achieve accurate diagnosis of tumor.In order to realize the biological application of nir-ii fluorescent probe,hydrophobic fluorescent molecules are usually self-assembled by amphiphilic polymers to prepare water-soluble nanoparticles.Nir-i fluorescence imaging technology can also be used to guide the synergistic treatment of chemotherapy and phototherapy.	price>
R-R-2631	Pirfenidone-d5 CAS No.1020719-62-3	Pirfenidone-d5/CAS No.1020719-62-3 is a deuterium labeled Pirfenidone. Pirfenidone is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines. Pirfenidone also has anti-inflammatory activities.	price>
R-C-932	Sulfo-Cy7 maleimide	Sulfo-Cy7 maleimide is water soluble cyanine dye containing a maleimide group which is commonly reacted with thiols to form a thioester bond at pH 6.5 to 7.5. This NIR dye amine can be used to derivate various targets by the reaction with electrophilic groups,and by enzymatical reactions involving transamination.	price>
R-R-2632	Mongersen CAS No.1443994-46-4	Mongersen (GED-0301)/CAS No.1443994-46-4 is a specific and orally active SMAD7 antisense oligonucleotide. Mongersen restores TGF-β1 activity leading to inhibition of inflammatory signals.	price>
R-C-933	Liposome surface modified DTPA / FITC	Liposome has a certain targeting property,while modified liposome has more active targeting property and stronger anticancer property,which is a new technology that has been studied more at present.	price>
R-R-2633	Elezanumab CAS No.1791416-49-3	Elezanumab (ABT-555; AE12-1Y-QL)/CAS No.1791416-49-3 is a human monoclonal antibody that selectively targets repulsive guidance molecule A (RGMa). Elezanumab potently inhibited RGMa mediated BMP signalling via the SMAD1/5/8 pathway, with an IC50 around 97 pM. Elezanumab promotes neuroregeneration and neuroprotection in neuronal injury and demyelination models binds N-terminal RGMa, blocks BMP signaling and lacks RGMc cross-reactivity. elezanumab has neuroregenerative and neuroprotective activities without impact on iron metabolism.	price>
R-C-934	Graphene oxide grafted polypeptide（WKYMVm）	Polypeptides as receptor targeted anti-tumor carriers are more and more used to improve the effect of chemotherapy drugs.It has also been proved that polypeptides can improve the anti-tumor effect by enhancing the targeting specificity of drugs,enhancing the targeted absorption of drugs,and improving the original insoluble of some small molecule drugs.Peptide carrier targeting technology is known as a new generation of targeted drug development technology. Graphene oxide is the oxide of graphene,which is generally represented by go. Its color is brown yellow.The common products on the market are powder,flake and solution.	price>
R-R-2634	IDE 2 CAS No.1136466-93-7	IDE2/CAS No.1136466-93-7 is a small molecule cell-permeable inducer of definitive endoderm formation in mouse and human embryonic stem cells (ESCs) by activating the TGF-βsignaling pathway.	price>
R-D-935	DMG-PEG2000-transferrin	DMG-PEG2000,1,2-Dimyristoyl-sn-glycerol-methoxypolyethylene glycol-2000,is a lipid and peg conjugate.DMG-PEG2000 has been used with cationic lipids such as Dlin-MC3-DMA to form cationic nanoparticles that can encapsulate and deliver siRNA,mRNA,DNA or small molecules into the cytoplasm and represent the most advanced delivery platforms for systemic administration of active molecules.	price>
R-R-2635	Hydrochlorothiazid-d2 CAS No.1219798-89-6	Hydrochlorothiazid-d2/CAS No.1219798-89-6 is the deuterium labeled Hydrochlorothiazide. Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect.	price>
R-C-936	DOTA-TAT（YGRKKRRQRRR）	tetraazacyclo-dodecanetetra-acetic acid-TAT（YGRKKRRQRRR) microcyclic carrier core significantly enhances intraocular penetrance of multiple drugs.It carries the advantages of small size,targeted intracellular drug delivery and non-invasive monitoring of therapeutic agents.Intraocular delivery of anti-VEGF agents can be one of its immediate applications.	price>
R-R-2636	Hydrochlorothiazid-13C,d2 CAS No.1190006-03-1	Hydrochlorothiazid-13C,d2/CAS No.1190006-03-1 is the 13C- and deuterium labeled Hydrochlorothiazide. Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect.	price>
R-C-937	Methyltetrazine-OH	(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.	price>
R-R-2637	Hydrochlorothiazide-13C6 CAS No.1261396-79-5	Hydrochlorothiazide-13C6/CAS No.1261396-79-5 is the 13C labeled Hydrochlorothiazide. Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect.	price>
R-R-2638	10,11-Dehydrocurvularin CAS No.21178-57-4	10,11-Dehydrocurvularin/CAS No.21178-57-4 is a prevalent fungal phytotoxin and an antibiotic. 10,11-Dehydrocurvularin is a strong activator of the heat shock response. 10,11-Dehydrocurvularin inhibits TGF-β signalling pathway. Anti-tumorous activity.	price>
R-C-939	HCPT-NHS	Camptothecin is a plant anticancer drug,light yellow needle like crystal. Camptothecin has good curative effect on gastrointestinal tract and head and neck cancer,but it has side effect of urination in a few patients.The anticancer activity of 10 hydroxycamptothecin is higher than that of camptothecin.It also has obvious curative effect on liver cancer and head and neck cancer with less side effects.	price>
R-R-2639	(Rac)-Upacicalcet CAS No.2649575-19-7	(Rac)-Upacicalcet/CAS No.2649575-19-7 is the racemate of Upacicalcet.Upacicalcet is an intravenous calcimimetic agent. Upacicalcet suppresses excessive parathyroid hormone (PTH) secretion, thereby lowering blood PTH levels, by acting directly on parathyroid cell membrane calcium-sensing receptors. Upacicalcet can be used for researching the disease of secondary hyperparathyroidism (SHPT).	price>
R-C-940	PAMAM-COOH (G4)	Dendrimer with positive charge surface(g4-pamam-nh2)and dendrimer with neutral surface(g4-pamam-oh)can inhibit the activity of pepsin.At the same time,it was found that these dendrimers were used as part of the mixed noncompetitive pepsin inhibitors.There was no correlation between pepsin activity and protein CD profile.	price>
R-R-2640	Gadolinium chloride CAS No.10138-52-0	Gadolinium chloride is a specific calcium-sensing receptor (CaSR) agonist. Gadolinium chloride can be used for the research of cardiovascular disease.	price>

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