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| Catalog | name | Description | price |
|---|---|---|---|
| R-C-961 | Encapsulation of paeonol with sp94 peptide liposome | Sp94(sfsiihtpilpl)can specifically bind with hepatoma cells.It has important clinical application by increasing apoptosis of hepatoma cells and inhibiting tumor angiogenesis.It can be used for systematic treatment of patients with early hepatoma.Paeonol has analgesic,anti-inflammatory,antipyretic and antiallergic effects.It has sedative,hypnotic,antibacterial,anti-inflammatory, antioxidant and antihypertensive effects,In the aspect of daily chemical, paeonol can inhibit the production of O2 free radicals in cells,whiten the skin, reduce the pigmentation in the skin,and remove stasis and spots;at the same time,it also has anti-inflammatory,anti swelling and analgesic,anti allergic and anti-virus effects. | price> |
| R-R-2661 | LY367385 hydrochloride CAS No.2829282-00-8 | LY367385 hydrochloride/CAS No.2829282-00-8 is a highly selective and potent mGluR1a antagonist. LY367385 hydrochloride has an IC50 of 8.8 μM for inhibiting of quisqualate-induced phosphoinositide (PI) hydrolysis, compared with >100 μM for mGlu5a. LY367385 hydrochloride has neuroprotective, anticonvulsant and antiepileptic effects. | price> |
| R-C-962 | Liposome loaded with paeonol | Liposomes are liposomes(hollow)made from lecithin and ceramide.They have the same bilayer structure as skin cell membrane and have excellent moisturizing effect on skin.Especially,liposomes coated with moisturizing substances such as hyaluronic acid and polyglucoside are more excellent moisturizing substances, Paeonol can inhibit the production of O2-free radicals in cells,whiten the skin, reduce the pigmentation in the skin,and remove stasis and spots;at the same time,it also has anti-inflammatory,anti swelling,analgesic,anti allergic and anti-virus effects. | price> |
| R-R-2662 | LY2794193 CAS No.2173037-97-1 | LY2794193/CAS No.2173037-97-1 is a highly potent and selective mGlu3 receptor agonist (hmGlu3 Ki=0.927 nM,EC50=0.47 nM; hmGlu2 Ki=412 nM,EC50=47.5 nM). | price> |
| R-C-963 | Inclusion of nucleic acid in sp94 peptide liposomes | Sp94(sfsiihtpilpl)can specifically bind with hepatoma cells,and has important clinical application by increasing apoptosis and inhibiting tumor angiogenesis. It can be used for systematic treatment of patients with early hepatoma.Nucleic acid is a kind of biopolymer,which is an essential component of all known life forms and the most important substance in all biomolecules In all animal and plant cells,microbial body. | price> |
| R-R-2663 | LY404039 CAS No.635318-11-5 | LY404039/CAS No.635318-11-5 is a potent, selective and orally active mGluR2 and mGluR3 agonist with Kis of 149 nM and 92 nM for recombinant human mGluR2 and mGluR3, respectively. LY404039 shows >100-fold selectivity for mGluR2/3 over other receptors/transproters. LY404039 has antipsychotic and anxiolytic effects. | price> |
| R-C-964 | Liposome containing nucleic acid | Liposomes are hollow liposomes made from lecithin and ceramide.They have the same bilayer structure as skin cell membrane and have excellent moisturizing effect on skin.Especially,liposomes coated with moisturizing substances such as hyaluronic acid and polyglucoside are more excellent moisturizing substances. Nucleic acid is a kind of biopolymer,which is essential for all known life forms The indispensable component is the most important substance in all biological molecules,which widely exists in all animal and plant cells and microorganisms. | price> |
| R-R-2664 | (S)-MCPG CAS No.150145-89-4 | (S)-MCPG ((+)-MCPG)/CAS No.150145-89-4 is a potent group I/II metabotropic glutamate receptor (mGluRs) antagonist and the active isomer of (RS)-MCPG (HY-100371). (S)-MCPG can be used for the study of the function of mGluRs in spatial learning. | price> |
| R-C-965 | Polyamindoamine G5-polyethylene glycol-Vancomycin | Polyamide amine dendrimer(PAMAM)is a kind of highly branched and symmetrical nano scale polymer compound.The cavity inside the molecule can be used to encapsulate drug molecules,and the terminal group can be modified to connect ligands,antibodies and other bioactive substances.The high density positive charge of the molecule can compress DNA.The molecular weight of 2K and 5K MPEG SC was used to bind G5 PAMAM was modified with two kinds of amino groups.The number of PEG with low degree of substitution was 13,and that with high degree of substitution was 51,which was 10% and 40% of the amino groups on the surface of g5pamam,respectively.Vancomycin(Van)is a kind of glycopeptide antibiotics. Its binding ability with target bacteria is equal to that of antigen antibody. It has the advantages of good stability,easy preparation and preservation. | price> |
| R-R-2665 | MMPIP hydrochloride CAS No.1215566-78-1 | MMPIP hydrochloride/CAS No.1215566-78-1 is an allosteric metabotropic glutamate receptor 7 (mGluR7) selective antagonist (KB values 24 -30 nM). MMPIP hydrochloride acts as a pharmacological tool for elucidating the roles of mGluR7 on central nervous system functions. MMPIP hydrochloride alleviates pain and normalizes affective and cognitive behavior in neuropathic mice. | price> |
| R-C-966 | MS275-CY5.5 | MS-275 is a histone deacetylase inhibitor that has shown potent and unique anticancer activity in preclinical models.The aims of this phase I trial were to determine the dose-limiting toxicities and maximum tolerated dose of oral MS-275 in humans administered with food on a once weekly schedule and to study the pharmacokinetics of oral MS-275. | price> |
| R-R-2666 | Mavoglurant CAS No.543906-09-8 | Mavoglurant (AFQ056)/CAS No.543906-09-8 is a potent, selective, non-competitive and orally active mGluR5 antagonist, with an IC50 of 30 nM. Mavoglurant shows a >300 fold selectivity for the mGluR5 over all targets (238) tested. Mavoglurant is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | price> |
| R-C-967 | BocNH2-TK-NH2 | Palladium catalyzed Buchwald Hartwig amination with BocNH2 as amine source and palladium catalyzed Hiyama coupling reaction of 2-trimethylsilylpyridine with brominated aromatic hydrocarbons.Palladium catalyzed Buchwald Hartwig amination with bocnh2 as amine source.The effects of catalyst,ligand,base,solvent and temperature on the reaction were investigated. | price> |
| R-R-2667 | Dipraglurant CAS No.872363-17-2 | Dipraglurant (ADX48621)/CAS No.872363-17-2 is a potent, selective, orally active and brain penetrant mGluR5 negative allosteric modulator (NAM), with an IC50 of 21 nM. Dipraglurant can reduce Levodopa-induced dyskinesia (LID) in vivo. Dipraglurant is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | price> |
| R-C-968 | 25 hydroxyvitamin D-nhs | 25 hydroxyvitamin D(25 hydroxyvitamin d)is a kind of sterol hormone,which plays an important role in promoting the absorption of calcium in the intestine and maintaining its dynamic balance.It plays a key role in the growth and health of human bones.Vitamin D not only has skeletal effects,but also has non skeletal effects related to autoimmune diseases,diabetes,cardiovascular diseases,cell growth and differentiation.Vitamin D3 can be synthesized from skin tissue exposed to ultraviolet light. | price> |
| R-R-2668 | L-Glutamine-15N-1 CAS No.59681-32-2 | L-Glutamine-15N-1/CAS No.59681-32-2 is the 15N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells. | price> |
| R-C-969 | N-nervonoyl-D-erythro-sphingosylphosphorylcholine, powder | Ceramide is a family of waxy lipid molecules.Ceramide is composed of a sphingosine molecule and a fatty acid molecule.Ceramide has a high concentration in the cell membrane of eukaryotic cells,because it is the main component of phospholipid bilayer-sphingomyelin.Phosphorylcholine is an amphoteric molecule composed of a hydrophilic head and a hydrophobic tail.Also known as lecithin. Phosphatidylcholine is one of the main components of phospholipids,which is extracted from plants. | price> |
| R-R-2669 | RO0711401 CAS No.714971-87-6 | RO0711401/CAS No.714971-87-6 is a selective and orally active positive allosteric modulator of mGlu1 receptor with an EC50 of 56 nM. | price> |
| R-C-970 | Oil soluble nano iron star (particle size below 50nm) | Nano iron is the iron formed by the superposition of iron atoms one by one according to the nanometer level(e-9m).There is no difference in physical properties,but the difference is in chemical properties.For example,ordinary iron will not easily burn,but nano iron can spontaneously ignite in the air; ordinary iron has weak corrosion resistance,while nano iron has corrosion resistance. | price> |
| R-R-2670 | Foliglurax monohydrochloride | Foliglurax monohydrochloride (PXT002331 monohydrochloride) is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) , with an EC50 of 79 nM. Antiparkinsonian effect. | price> |

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