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Catalog	name	Description	price
R-R-2812	Adomeglivant CAS No.1488363-78-5	Adomeglivant (LY2409021)/CAS No.1488363-78-5 is a potent, selective glucagon receptor (GluR) allosteric antagonist. Adomeglivant is widely used in the research for type 2 diabetes mellitus.	price>
R-C-1113	AC710 CAS:1351522-04-7	AC710 is a potent,orally active,and selective platelet-derived growth factor receptor-family kinase inhibitor with potential anticancer activity.	price>
R-R-2813	GLP-1(7-37) acetate CAS No.1450806-98-0	GLP-1(7-37) acetate/CAS No.1450806-98-0 is an intestinal insulinotropic hormone that augments glucose induced insulin secretion.	price>
R-C-1114	AC5216 CAS：226954-04-7	Emapunil(AC-5216,18 kiloDalton Translocator Protein,XBD173)is a novel mitochondrial benzodiazepine receptor/translocator protein (MBR/TSPO)ligand. Emapunil(AC-5216)showes high affinity for MBRs prepared from rat whole brain with Ki of 0.297 nM and IC50 of 3.04 nM and 2.73 nM at rat glioma cells and human glioma cells,respectively.	price>
R-R-2814	Semaglutide TFA	Semaglutide TFA, a long-acting GLP-1 analogue, is a glucagon-like peptide-1 (GLP-1) receptor agonist. Semaglutide TFA has the potential for type 2 diabetes treatment.	price>
R-C-1115	SD208 CAS：627536-09-8	SD-208 is a potent,orally active ATP-competitive transforming growth factor-β receptor 1(TGF-βRI)inhibitor(IC50=49 nM);displays>100-fold and>17-fold selectivity over TGF-βRII and other common kinases respectively.	price>
R-R-2815	BETP CAS No.1371569-69-5	BETP/CAS No.1371569-69-5 is an agonist of glucagon-like peptide-1 (GLP-1) receptor, with EC50s of 0.66 and 0.755 μM for human and rat GLP-1 receptor, respectively.	price>
R-C-1116	RGB-286638 CAS： 784210-87-3	RGB-286638 is a CDK inhibitor that inhibits the kinase activity of cyclin T1-CDK9,cyclin B1-CDK1,cyclin E-CDK2,cyclin D1-CDK4,cyclin E-CDK3,and p35-CDK5 with IC50s of 1,2,3,4,5 and 5 nM,respectively;also inhibits GSK-3β,TAK1,Jak2 and MEK1,with IC50s of 3,5,50,and 54 nM.	price>
R-C-2816	mPEG-Hyd-PLGA	PEG-PLGA is an amphiphilic AB diblock copolymer whose axis is hydrophilic(block glycolide)(PLGA)composition Peg polymer was terminated with methyl ether group and hydrophobic block was terminated with hydroxyl group.It has biological characteristics.	price>
R-R-2816	GLP-1(9-36)amide CAS No.161748-29-4	GLP-1(9-36)amide/CAS No.161748-29-4 is a major metabolite of glucagon-like peptide-1-(7-36) amide formed by the enzyme dipeptidyl peptidase-4 (DPP-4). GLP-1(9-36)amide acts as an antagonist to the human pancreatic GLP-1 receptor.	price>
R-C-1117	HTH-01-015 CAS:1613724-42-7	HTH-01-015 is a selective NUAK1/ARK5 inhibitor(IC50 is 100 nM).HTH-01-015 inhibits NUAK1 with>100-fold higher potency than NUAK2(IC50 of >10μM).	price>
R-C-2817	Cholesterol-peg-galactose	Cholesterol is an indispensable material for animal tissues and cells.It not only participates in the formation of cell membrane,but also is the raw material for the synthesis of bile acids,vitamin D and steroids.Galactose is a monosaccharide composed of six carbons and one aldehyde,which is classified as aldose and hexose.	price>
R-R-2817	GLP-1R Antagonist 1 CAS No.488097-06-9	GLP-1R Antagonist 1 (compound 5d)/CAS No.488097-06-9 is an orally active, CNS penetrant and non-competitive antagonist of glucagon-like peptide 1 receptor (GLP-1R), with an IC50 of 650 nM.	price>
R-C-1118	Defactinib(VS6063,PF-04554878) CAS:1073154-85-4	Defactinib(VS-6063;PF-04554878)is a novel FAK inhibitor with potential antiangiogenic and antineoplastic activities.	price>
R-C-2818	PLL-PEG-Modified gold nanoparticles（5nm）	Poly(L-lysine)is a light yellow powder with strong moisture absorption and slightly bitter taste.It is a linear polymer of lysine.Poly(L-lysine)is soluble in water and slightly soluble in ethanol.	price>
R-R-2818	Cotadutide acetate	Cotadutide (MEDI0382) acetate is a potent dual agonist of glucagon-like peptide-1 (GLP-1) and GCGR with EC50 values of 6.9 pM and 10.2 pM, respectively. Cotadutide acetate exhibits ability to facilitate both weight loss and glycaemic control, and alleviate fibrosis. Cotadutide acetate can be used in the research of obesity and type 2 diabetes (T2D).	price>
R-C-1119	Liproxstain-1 CAS :950455-15-9	Liproxstatin-1 is an iron droop inhibitor.At a concentration of 50 nm,GPx4-/- MEFs inhibited the iron drooping cell death(IC50=22 nm)and lipid peroxidation of mouse embryonic fibroblasts(MEFs)by inducible knockout of glutathione peroxidase 4(GPx4-/-MEFs).Liproxstatin-1 also inhibited the iron ptosis induced by iron ptosis inducers L-buthionine sulfoxime(BSO),erastine and (1s,3R)-rsl3 in a concentration dependent manner,but did not inhibit necrotic ptosis,apoptosis or necrosis.Inhibition of(1s,3R)-rsl3 induced cell death and lipid peroxidation in human renal proximal tubular epithelial cells.Liproxstatin-1 (10mg/kg)increased survival rate and decreased TUNEL+renal cells in induced GPx4 -/-mice,and reduced tissue damage in liver ischemia/reperfusion injury mice.It is also an antioxidant that inhibits lipid autoxidation by capturing peroxyradicals.	price>
R-C-2819	Red fluorescence of carbon quantum dots	Carbon quantum dots not only have the common fluorescence characteristics of quantum dots,but also have good stability and high biocompatibility.They are widely used in biomedical fields, such as cell labeling,optical imaging,drug delivery and biosensor.	price>
R-R-2819	Beinaglutide CAS No.123475-27-4	Beinaglutide/CAS No.123475-27-4 is a human GLP-1 polypeptide that shares almost 100% homology with human GLP-1 (7–36). Beinaglutide displays does-dependent effects in glycemic control, inhibiting food intake and gastric empty and promoting weight loss. Beinaglutide has the potential for the research of overweight/obesity and nonalcoholic steatohepatitis (NASH).	price>
R-C-1120	Radotinib(IY-5511) CAS:926037-48-1	Radotinib is a selective second generation tyrosine kinase inhibitor that targets both the wild-type and mutant forms of Bcr-Abl,with an IC50 value of 30.6 nM in Ba/F3 human chronic myeloid leukemia cells expressing the wild-type form.Radotinib also inhibits platelet-derived growth factor receptors(PDGFRs)α and β with IC50 values of 75.5 and 130 nM,respectively.Binding of radotinib to Bcr-Abl in vitro inhibits the phosphorylation of the downstream signaling mediator CrkL.3 In acute myeloid leukemia cells,in vitro treatment with radotinib at doses of 10-100 µM reduces viability,activates the mitochondrial apoptosis pathway,and promotes expression of the differentiation marker CD11b.	price>

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