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R-C-2820 Green fluorescence of carbon quantum dots Carbon quantum dots not only have the common fluorescence characteristics of quantum dots,but also have good stability and high biocompatibility.They are widely used in biomedical fields,such as cell labeling, optical imaging,drug delivery and biosensor. price>
R-R-2820 GLP-2(1-33)(human) CAS No.223460-79-5 GLP-2(1-33) (human)/CAS No.223460-79-5 is an enteroendocrine hormone which can bind to the GLP-2 receptor and stimulate the growth of intestinal epithelium. price>
R-C-1121 SKF-86002 CAS:72873-74-6 SKF-86002 is an orally active p38 MAPK inhibitor,with anti-inflammatory,anti-arthritic and analgesic activities.SKF-86002 inhibits lipoxygenase- and cyclooxygenase-mediated metabolism of arachidonic acid. price>
R-C-2821 CY5-Black phosphorus nanoparticles(100nm) Black phosphorus,a new two-dimensional nano material, has excellent photothermal properties and biodegradability.It is a potential drug carrier material.It has good solvent dispersion(water,acetone,alcohols,NMP,DMF,etc.) and relatively high singlet oxygen quantum yield (about 0.91). price>
R-R-2821 Lotiglipron CAS No.2401892-75-7 Lotiglipron (PF-07081532)/CAS No.2401892-75-7 is an orally active GLP-1R agonist. Lotiglipron reduces glucose and body weight, and can be used for research of Type 2 diabetes mellitus (T2DM). price>
R-C-1122 EPZ015666 (GSK3235025) CAS:1616391-65-1 Protein arginine methyltransferases(PRMTs)target nuclear and cytoplasmic substrates and can alter protein actions and gene expression.PRMT5,which can methylate histones H2A,H3,and H4,ribonucleoproteins,and other proteins,is upregulated in several human cancers,including lymphomas.Moreover,suppression of PRMT5 expression induces lymphoma cell death.EPZ015666 is a potent,orally bioavailable inhibitor of PRMT5(Ki=5nM).It displays more than 20,000-fold selectivity for PRMT5 over other PMTs.EPZ015666 acts by blocking the association of PRMT5 with methylosome protein 50,which is necessary for the formation of an active methyltransferase complex. price>
R-C-2822 PLL5k-g-PEG5k-MAL Polylysine linked polyethylene glycol.and the other end of polyethylene glycol modified maleimide.It can be used for passive targeting of micelles and vesicles,active targeting research and drug delivery. price>
R-R-2822 Exendin-4 acetate CAS No.914454-01-6 Exendin-4 acetate (Exenatide acetate)/CAS No.914454-01-6, a 39 amino acid peptide, is a long-acting glucagon-like peptide-1 receptor agonist with an IC50 of 3.22 nM. price>
R-C-1123 Dorsomorphin (Compound C) 2HCl Dorsomorphin 2HCl(BML-275,Compound C)is a potent,reversible, selective AMPK inhibitor with Ki of 109 nM in cell-free assays,exhibiting no significant inhibition of several structurally related kinases including ZAPK,SYK,PKCθ, PKA,and JAK3.Also inhibits type Ⅰ BMP receptor activity.Dorsomorphin induces autophagy in cancer cell line. price>
R-C-2823 Yeast glucan-Schiff Base-PEI25K-FITC Yeast glucan is a polysaccharide with immune enhancing activity in yeast cell wall β-Dextran.β- Glucan widely exists in various fungi and plants,such as yeast,Lentinus edodes,Ganoderma lucidum and oats.It is the main functional substance for them to play a role in health care. Schiff base mainly refers to a class of organic compounds containing imine or methylimine characteristic groups(-RC=n-).Usually,Schiff base is formed by condensation of amine and active carbonyl It has excellent liquid crystal properties.Used as organic synthetic reagent and liquid crystal material. price>
R-R-2823 Retatrutide TFA Retatrutide (LY3437943) TFA is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide TFA binds human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively. Retatrutide TFA can be used for the research of obesity. price>
R-C-1124 PF06447475 CAS:1527473-33-1 PF06447475 is a highly potent,selective,brain penetrant,and in vivo active LRRK2 kinase inhibitor.Leucine rich repeat kinase 2(LRRK2)has been genetically linked to Parkinson disease(PD)by genome-wide association studies(GWAS).The most common LRRK2 mutation,G2019S,which is relatively rare in the total population,gives rise to increased kinase activity.As such,LRRK2 kinase inhibitors are potentially useful in the treatment of PD. price>
R-C-2824 Yeast glucan-PEI25K-FITC Yeast glucan is a polysaccharide with immune enhancing activity in yeast cell wall β- Dextran.β- Glucan widely exists in various fungi and plants,such as yeast,Lentinus edodes,Ganoderma lucidum and oats.It is the main functional substance for them to play a role in health care.Schiff base mainly refers to a class of organic compounds containing imine or methylimine characteristic groups(-RC=n-).Usually,Schiff base is formed by condensation of amine and active carbonyl It has excellent liquid crystal properties.Used as organic synthetic reagent and liquid crystal material. price>
R-R-2824 LGD-6972 CAS No.1207989-09-0 LGD-6972/CAS No.1207989-09-0 is a selective and orally active glucagon receptor antagonist. LGD-6972 has the potential for type 2 diabetes research. price>
R-C-1125 SP2509 CAS:1423715-09-6 Soluble in DMSO.LSD1 is a promising target for cancer therapy.Epigenetic control of histone methylation is frequently associated with oncogenesis and LSD1 is overexpressed in many types of cancer.siRNA knockdown of LSD1 has been shown to suppress growth of cancer cells.SP-2528 is a selective and reversible LSD1 inhibitor with an IC(50)of 10nM.SP-2528 demonstrates a high specificity for LSD1,with no effect on MAOi.Target:LSD1. price>
R-C-2825 DSPE-PEG2000-MMP9 MMP9 protein;Selection of fusion label of matrix metalloproteinase 9(MMP9) recombinant protein:affinity label:the fusion expression of affinity label plays two roles in the process of protein recombinant expression:on the one hand,it is to make the process of protein purification easier;On the other hand,it is to promote the solubility of some insoluble proteins. price>
R-R-2825 NNC-0640 CAS No.307986-98-7 NNC-0640/CAS No.307986-98-7 is a potent human G-protein-coupled glucagon receptor (GCGR) negative allosteric modulator (NAM) with an IC50 of 69.2 nM. price>
R-C-1126 Molidustat(BAY85-3934) CAS:1154028-82-6 Molidustat,also known as BAY 85-3934,is a novel inhibitor of hypoxia-inducible factor(HIF)prolyl hydroxylase(PH)which stimulates erythropoietin(EPO)production and the formation of red blood cells.Phase I data have shown that inhibition of HIF-PH by Molidustat results in an increase in endogenous production of EPO. price>
R-C-2826 DSPE-PEG1K-L-thyroxine Thyroid stimulating hormone(TSH)is a hormone synthesized and secreted by the pituitary gland.It functions by binding with thyroid stimulating hormone receptor(TSHR).PEG lipid conjugate DSPE peg is not only widely used as a self-assembly material for anticancer drug delivery,but also as an additive material for surface functionalization of various drug delivery systems. price>
R-R-2826 Lixisenatide acetate CAS No.1997361-87-1 Lixisenatide acetate/CAS No.1997361-87-1 is a glucagon-like peptide-1 (GLP-1) receptor agonist that can be used in the treatment of type 2 diabetes mellitus (T2DM). price>