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Catalog	name	Description	price
R-C-1157	CIQ CAS:486427-17-2	CIQ is a GluN2C/GluN2D subunit-selective NMDA receptor potentiator,which reverses MK-801-induced impairment in prepulse inhibition and working memory in Y-maze test in mice.The facilitation of GluN2C/GluN2D-containing receptors may serve as an important therapeutic strategy for treating positive and cognitive symptoms in schizophrenia.	price>
R-R-2857	HAEGTFTSDVS CAS No.864915-61-7	HAEGTFTSDVS/CAS No.864915-61-7 is the first N-terminal 1-11 residues of GLP-1 peptide.	price>
R-C-1158	Pexidartinib (PLX-3397) CAS:1029044-16-3	Pexidartinib(PLX-3397)is a potent, orally active,selective, and ATP-competitive colony stimulating factor 1 receptor(CSF1R or M-CSFR)and c-Kit inhibitor,with IC50s of 20 and 10 nM respectively.Pexidartinib(PLX-3397) exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases.Pexidartinib(PLX-3397)induces cell apoptosis and has anti-tumor activity.	price>
R-R-2858	GLP-1R agonist 3 CAS No.2428640-18-8	GLP-1R agonist 3/CAS No.2428640-18-8 is a potent agonist of GLP-1R. GLP-1R agonist 3 is a thickened imidazole derivative compound. Glucagon-like peptide-1 (GLP-1) is an intestinal hypoglycemic hormone secreted by L-cells in the lower gastrointestinal tract. GLP-1R agonist 3 has the potential for the research of diabetes (extracted from patent WO2021197464A1, compound 1).	price>
R-C-1159	omarigliptin CAS:1226781-44-7	Omarigliptin(MK-3102)is a competitive,reversible inhibitor of DPP-4(IC50=1.6 nM,Ki=0.8nM).It is highly selective over all proteases tested (IC50>67 μM), including QPP,FAP,PEP,DPP8,and DPP9 and has weak ion channel activity (IC50>30 μM at IKr,Caγ1.2,and Naγ1.5).	price>
R-R-2859	Glucagon receptor antagonists-1 CAS No.503559-84-0	Glucagon receptor antagonists-1/CAS No.503559-84-0 is a highly potent glucagon receptor antagonist.	price>
R-C-1160	Anacetrapib (MK-0859) CAS:875446-37-0	Anacetrapib,also known as MK-0859,is a CETP inhibitor being developed to treat hypercholesterolemia(elevated cholesterol levels)and prevent cardiovascular disease.	price>
R-R-2860	GCGR antagonist 2 CAS No.280134-25-0	GCGR antagonist 2/CAS No.280134-25-0, a Furan-2-carbohydrazide, is an orally active glucagon receptor antagonist. GCGR antagonist 2 binds to hGluR with an Kd value of 2.3 nM, and inhibits rat receptor with an IC50 value of 0.43 nM. GCGR antagonist 2 inhibits glucagon-stimulated glycogenolysis.	price>
R-C-1161	Felbamate CAS:25451-15-4	Felbamate(W-554)is a potent nonsedative anticonvulsant whose clinical effect may be related to the inhibition of N-methyl-D-aspartate(NMDA).	price>
R-R-2861	Exendin-3/4 (59-86) CAS No.1263874-37-8	Exendin-3/4 (59-86)/CAS No.1263874-37-8 is a Exendin-4 peptide derivative.	price>
R-C-1162	BMS-687453 CAS:1000998-59-3	BMS-687453 is a potent and selective peroxisome proliferator activated receptor (PPAR)alpha agonist. with an EC(50)of 10 nM for human PPARalpha and approximately 410-fold selectivity vs human PPARgamma in PPAR-GAL4 transactivation assays.BMS-687453 demonstrated an excellent pharmacological and safety profile in preclinical studies and thus was chosen as a development candidate for the treatment of atherosclerosis and dyslipidemia.	price>
R-R-2862	{Val1}-Exendin-3/4	{Val1}-Exendin-3/4 is the first N-terminal 1-28 residues of Exendin-4 peptide.	price>
R-C-1163	OPC 21268 CAS:131631-89-5	OPC21268 is a non-peptide AVP Receptor V(Vasopressin Receptor)antagonist that shows 1000-fold selectivity for V1 receptors over V2 receptors.	price>
R-R-2863	(1R,5S,6S)-Tert-butyl CAS No.:273206-92-1	6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate CAS No.:273206-92-1 The mode of action of (1R,5S,6S)-Tert-butyl 6-amino-3-azabicyclo[31It is known that the compound is synthesized via a palladium-catalyzed cyclopropanation of maleimides with n-tosylhydrazones . The interaction of this compound with its potential targets and the resulting changes are subjects of ongoing research.	price>
R-C-1164	GW9662 CAS: 22978-25-2	GW9662 is a potent and selective PPARγ antagonist with an IC50 of 3.3 nM, showing 10 and 1000-fold selectivity over PPARα and PPARδ,respectively.	price>
R-R-2864	GLP-1 (1-36) amide (human, rat) (TFA)	GLP-1 (1-36) amide (human, rat) (Glucagon-like Peptide 1 (1-36) amide (human, rat) ) TFA is a molecular variant of glucagon-like peptide 1 (GLP-1)-(7-36) amide. GLP-1 (1-36) amide (human, rat) TFA can stimulate [14C]aminopyrine accumulation on enzymatically dispersed enriched rat parietal cells.	price>
R-C-1165	Coelenterazine H CAS:50909-86-9	Coelenterazine h is a derivative of Coelenterazine.Coelenterazine h is more sensitive to Ca2+than is the native complex,thus providing a valuable tool for measuring small changes in Ca2+concentrations.	price>
R-R-2865	SAR441255 TFA	SAR441255 TFA is a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist. SAR441255 TFA displays high potency with balanced activation of all three target receptors.?SAR441255 TFA shows positive acute glucoregulatory effectss in diabetic obese monkeys.	price>
R-C-1166	AI-10-49 CAS:1256094-72-0	AI-10-49 is a protein-protein interaction inhibitor that selectively binds to CBFβ-SMMHC and disrupts its binding to RUNX1 with a FRET IC50 of 0.26 uM.	price>
R-R-2866	V-0219 CAS No.878453-71-5	V-0219 (Compound 9)/CAS No.878453-71-5 is an orally active, positive allosteric modulator (PAM) of the glucagon-like peptide-1 receptor (GLP-1R). V-0219 can be used for obesity-associated diabetes research.	price>

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