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Catalog	name	Description	price
R-C-1187	SR9243 CAS :1613028-81-1	SR9243 is a potent and selective LXR inverse agonist.SR9243 kills cancer cells by inhibiting lipid production and the Warburg effect.It induces cell death in multiple types of cancer and does not cause the side effects that have derailed previous attempts to target these processes.	price>
R-R-2887	KH7 CAS No.330676-02-3	KH7/CAS No.330676-02-3 is a specific double adenyl cyclone (sAC) inhibitor, with IC50s of 3-10 μM toward both purified human sACT recombinant proteins and highly expressed sACT terolog in cellular assays KH7 is also a cAMP inhibitor	price>
R-C-1188	SB742457 CAS: 607742-69-8	Intepirdine,also known as SB-742457 and RVT-101,is a selective 5-HT6 receptor antagonist with potential cognition,memory,and learning-enhancing effects.It was under development by GlaxoSmithKline for the treatment of Alzheimer is disease and demonstrated some preliminary efficacy in phase II clinical trials.SB742457 can reverse age-related declines in delayed non-match-to-sample performance (DNMS).SB742457 shows increasing pro-cognitive effects in patients with AD.	price>
R-R-2888	LRE1 CAS No.1252362-53-0	LRE1/CAS No.1252362-53-0 is a specific and allosteric inhibitor of soluble adenylyl cyclase.	price>
R-C-1189	ITD-1 CAS:1099644-42-4	ITD-1 is a selective inhibitor of TGF-β signaling (IC50=0.85μM);displays little or no inhibition of activin,Wnt or BMP signaling pathways.ITD-1 selectively enhanced the differentiation of uncommitted mesoderm to cardiomyocytes,but not to vascular smooth muscle and endothelial cells.ITD-1 is a highly selective TGF-β inhibitor and reveals an unexpected role for TGF-β signaling in controlling cardiomyocyte differentiation from multipotent cardiovascular precursors.	price>
R-R-2889	TDI-10229 CAS No.2810887-45-5	TDI-10229/CAS No.2810887-45-5 is a potent and orally bioavailable inhibitor of soluble adenylyl cyclase (sAC, ADCY10). TDI-10229 displays nanomolar inhibition of sAC in both biochemical and cellular assays (IC50 of 195 nM) and exhibits mouse pharmacokinetic properties sufficient to warrant its use as an in vivo tool compound.	price>
R-C-1190	LRRK2-IN-1 CAS:1234480-84-2	LRRK2-IN-1 is a potent and selective LRRK2 inhibitor with IC50 of 6 nM and 13 nM for LRRK2(G2019S)and LRRK2(WT),respectively.	price>
R-R-2890	Fipexide CAS No.34161-24-5	Fipexide/CAS No.34161-24-5, a parachloro-phenossiacetic acid derivative, is an orally active nootropic agent. Fipexide reduces striatal adenylate cyclase activity. Fipexide has positive effect on cognitive performance by dopaminergic neurotransmission. Fipexide is used for senile dementia research. Fipexide acts as a chemical inducer in callus formation, shoot regeneration and Agrobacterium infection.	price>
R-C-1191	CP465022HCl CAS:199655-36-2	CP-465022 is a potent,and selective noncompetitive AMPA receptor antagonist.It provides neuroprotective efficacy after cerebral ischemia on the basis of the activity in experimental ischemia models.	price>
R-R-2891	SKF-83566 CAS No.99295-33-7	SKF-83566/CAS No.99295-33-7 is a potent, blood-brain permeable and orally active D1-like dopamine receptor (D1DR) antagonist and a weaker competitive antagonist at the vascular 5-HT2 receptor (Ki=11 nM). SKF-83566 is a competitive DAT (dopamine transporter) inhibitor with an IC50 of 5.7 μM. SKF-83566 also shows selective inhibition for adenylyl cyclase 2 (AC2) over AC1 and AC5 in the isolated rabbit thoracic aorta.	price>
R-C-1192	RQ-00203078 CAS:1254205-52-1	RQ-00203078 is a highly selective,potent and orally available TRPM8 antagonist (IC50 values are 5.3 and 8.3 nM for rat and human channels respectively), exhibits>350-fold selectivity for TRPM8 over TRPV4,TRPV1 and TRPA1.	price>
R-R-2892	ST034307 CAS No.133406-29-8	ST034307/CAS No.133406-29-8 is a potent and selective adenylyl cyclase 1 (AC1) inhibitor, with IC50 of 2.3 μM.	price>
R-C-1193	Kevetrin HCl	Kevetrin hydrochloride is a small molecule and activator of the tumor suppressor protein p53,with potential antineoplastic activity.	price>
R-R-2893	NKY80 CAS No.299442-43-6	NKY80/CAS No.299442-43-6 is a potent, selective and non-competitive adenylyl cyclase (AC) type V isoform inhibitor with IC50s of 8.3 µM, 132 µM and 1.7 mM for type V, III and II, respectively. NKY80 is a non-nucleoside quinazolinone and regulates the AC catalytic activity in heart and lung tissues.	price>
R-C-1194	LY310762 CAS:192927-92-7	LY310762 is a 5-HT1D antagonist with Ki of 249 nM, having a weaker affinity for 5-HT1B receptor.	price>
R-R-2894	Guanylyl imidodiphosphate lithium CAS No.64564-03-0	Guanylyl imidodiphosphate (Gpp(NH)p) lithium/CAS No.64564-03-0, a non-hydrolyzable GTP analogue, increases adenylate cyclase activity.	price>
R-C-1195	GSK-LSD1 CAS:2102933-95-7	GSK-LSD1 dihydrochloride is a potent,selective and irreversible lysine specific demethylase 1(LSD1)inhibitor with an IC50 of 16 nM.	price>
R-R-2895	TDI-11861 CAS No.2857049-72-8	TDI-11861/CAS No.2857049-72-8 is second-generation soluble Adenylyl Cyclase (sAC, ADCY10) inhibitor with slow dissociation rates. TDI-11861 inhibits sAC cellular with an IC50 value of 5.5 nM.	price>
R-C-1196	ORY-1001 CAS：1431326-61-2	ORY-1001 is an orally active and selective lysine-specific demethylase LSD1/KDM1A inhibitor with IC50 of <20 nM,with high selectivity against related FAD dependent aminoxidases.	price>
R-R-2896	Fipexide hydrochloride CAS No.34161-23-4	Fipexide hydrochloride/CAS No.34161-23-4, a parachloro-phenossiacetic acid derivative, is an orally active nootropic agent. Fipexide hydrochloride reduces striatal adenylate cyclase activity. Fipexide hydrochloride has positive effect on cognitive performance by dopaminergic neurotransmission. Fipexide hydrochloride is used for senile dementia research. Fipexide hydrochloride acts as a chemical inducer in callus formation, shoot regeneration and Agrobacterium infection.	price>

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