Xi'an ruixi Biological Technology Co

Home > Keywords >

Catalog	name	Description	price
R-C-1197	CPI-268456	CPI-268456 is a ligand of bromodomain-containing protein 4(BRD4).It binds to BRD4(IC5=<0.5 µM in a cell-free assay)and inhibits LPS-induced IL-6 secretion in THP-1 cells(IC50=<0.5 µM).	price>
R-R-2897	Lysipressin acetate CAS No.83968-49-4	Lysipressin (Lysine vasopressin) acetate/CAS No.83968-49-4 is antidiuretic hormone that have been found in pigs and some marsupial families. Lysipressin acetate induces contraction of the rabbit urinary bladder smooth muscle, activate adenylate-cyclase.	price>
R-C-1198	SW-033291 CAS：459147-39-8	SW033291 is a potent and high-affinity inhibitor of 15-PGDH with a Ki of 0.1 nM.SW033291 increases prostaglandin PGE2 levels in bone marrow and other tissues. SW033291 also promotes tissue regeneration.	price>
R-R-2898	9-Cyclopentyladenine monomethanesulfonate CAS No.189639-09-6	9-Cyclopentyladenine monomethylsulfonate (9-CP-Ade mesylate)/CAS No.189639-09-6 is a stable non-competitive adenylate cyclase inhibitor with cell permeable properties.	price>
R-C-1199	IBET762(GSK525762A) CAS ：1260907-17-2	Molibresib(I-BET-762,GSK525762,GSK525762A)is an inhibitor for BET proteins with IC50 of ~35 nM in a cell-free assay,suppresses the production of proinflammatory proteins by macrophages and blocks acute inflammation,highly selective over other bromodomain-containing proteins.	price>
R-R-2899	Zelminemab CAS No.2225850-33-7	Zelminemab (AMG-301)/CAS No.2225850-33-7 is a human monoclonal antibody that inhibits PACAP type I (PAC1) receptor.	price>
R-C-1200	GSK923295 Cytoskeletal Signaling	GSK-923295 is a special,allosteric inhibitor of centromere-associated protein-E (CENP-E)kinesin motor ATPase activity,with Ki of 3.2±0.2 nM and 1.6± 0.1 nM for human and canine,respectively.	price>
R-R-2900	CB-7921220 CAS No.115453-99-1	CB-7921220/CAS No.115453-99-1 is an adenylate cyclase inhibitor.	price>
R-C-1201	JZL-195 CAS:1210004-12-8	JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor with IC50 of 13 nM and 19 nM for mouse brain FAAH and MAGL respectively.	price>
R-R-2901	NB001 CAS No.686301-48-4	NB001 (HTS 09836)/CAS No.686301-48-4 is an adenylcyclase 1 (AC1) inhibitor which has effect on neural and non-neural pain by modulating AC1 activity.	price>
R-C-1202	MMAE CAS:474645-27-7	Dolastatin 10 is a natural antimitotic and antineoplastic agent that binds to tubulin and inhibits tubulin polymerization.1 Monomethyl Auristatin E(MMAE) is a synthetic analog of dolastatin 10 that similarly inhibits tubulin polymerization and exhibits potent cytotoxicity.It is commonly conjugated with monoclonal antibodies directed at antigens specific to cancer cells for tumor-directed cytotoxicity.2,3 MMAE is typically coupled to the antibody via a protease-cleavable linker,allowing separation of the drug from the antibody following intracellular localization.	price>
R-R-2902	Adenylyl cyclase type 2 agonist-1 CAS No.2414908-52-2	Adenylyl cyclase type 2 agonist-1 (Compound 73)/CAS No.2414908-52-2 is a potent agonist of adenylyl cyclase type 2 (AC2) with the EC50 of 90 nM. Adenylyl cyclase type 2 agonist-1 inhibits expression of Interleukin-6, making it a potential lead compound against respiratory diseases.	price>
R-C-1203	STF-31 CAS:724741-75-7	Glucose transporter 1(Glut1)is an inducible carrier of pentoses and hexoses, including glucose.STF-31 is an inhibitor of Glut1(IC50=~1 µM)that blocks glucose uptake.It induces necrosis in cancer cells that lack the von Hippel-Lindau tumor suppressor gene,which overexpress Glut1.1 Although STF-31 binds Glut1, suggesting a direct effect,STF-31 also inhibits nicotinamide phosphoribosyltransferase,an enzyme that induces Glut1 expression.STF-31 is also toxic to human pluripotent stem cells(hPSCs)and can be used to selectively eliminate hPSCs from mixed cultures.	price>
R-R-2903	Small Cardioactive Peptide B (SCPB) CAS No.84746-43-0	Small Cardioactive Peptide B (SCPB)/CAS No.84746-43-0, a neurally active peptide, stimulates adenylate cyclase activity in particulate fractions of both heart and gill tissues with EC50s of 0.1 and 1.0 μM, respectively.	price>
R-C-1204	Ostarine(MK2286) CAS:841205-47-8	Ostarine(GTx-024,MK-2866)is a selective androgen receptor modulator (SARM)with Ki of 3.8 nM,and is tissue-selective for anabolic organs.	price>
R-R-2904	Albanin A CAS No.73343-42-7	Albanin A/CAS No.73343-42-7, a flavonoid, suppresses glutamate release by decreasing Ca2+/calmodulin/adenylate Cyclase 1 (AC1) activation in synaptosomes and exerts neuroprotective effect in vivo. Albanin A has anti-inflflammatory activity.	price>
R-C-1205	Glycochenodeoxycholic acid CAS:640-79-9	Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) induces hepatocyte apoptosis.	price>
R-R-2905	Angiopeptin TFA CAS No.2478421-60-0	Angiopeptin TFA/CAS No.2478421-60-0, a cyclic octapeptide analogue of somatostatin, is a weak sst2/sst5 receptor partial agonist with IC50 values of 0.26 nM and 6.92 nM, respectively. Angiopeptin TFA is a potent inhibitor of growth hormone release and insulin-like growth factor-1 (IGF-1) production. Angiopeptin TFA inhibits adenylate cyclase or stimulates extracellular acidification. Angiopeptin TFA has the potential for coronary atherosclerosis research.	price>
R-C-1206	OTX015 CAS:202590-98-5	Birabresib(OTX015,MK 8628)is a potent BET bromodomain inhibitor with EC50 ranging from 10 to 19 nM for BRD2,BRD3,and BRD4 in cell-free assays. Birabresib inhibits the expression of Nuclear receptor binding SET domain protein 3(NSD3)target genes.	price>
R-R-2906	AC1-IN-1 CAS No.2762422-55-7	AC1-IN-1/CAS No.2762422-55-7 is a potent and selective Adenylyl cyclase type 1 (AC1) inhibitor with an IC50 of 0.54 µM. AC1-IN-1 displays modest antiallodynic effects in a mouse model of inflammatory pain. AC1-IN-1 has CNS activity.	price>

500501502503504505 506507508509510