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Catalog	name	Description	price
R-R-2895	TDI-11861 CAS No.2857049-72-8	TDI-11861/CAS No.2857049-72-8 is second-generation soluble Adenylyl Cyclase (sAC, ADCY10) inhibitor with slow dissociation rates. TDI-11861 inhibits sAC cellular with an IC50 value of 5.5 nM.	price>
R-C-1196	ORY-1001 CAS：1431326-61-2	ORY-1001 is an orally active and selective lysine-specific demethylase LSD1/KDM1A inhibitor with IC50 of <20 nM,with high selectivity against related FAD dependent aminoxidases.	price>
R-R-2896	Fipexide hydrochloride CAS No.34161-23-4	Fipexide hydrochloride/CAS No.34161-23-4, a parachloro-phenossiacetic acid derivative, is an orally active nootropic agent. Fipexide hydrochloride reduces striatal adenylate cyclase activity. Fipexide hydrochloride has positive effect on cognitive performance by dopaminergic neurotransmission. Fipexide hydrochloride is used for senile dementia research. Fipexide hydrochloride acts as a chemical inducer in callus formation, shoot regeneration and Agrobacterium infection.	price>
R-C-1197	CPI-268456	CPI-268456 is a ligand of bromodomain-containing protein 4(BRD4).It binds to BRD4(IC5=<0.5 µM in a cell-free assay)and inhibits LPS-induced IL-6 secretion in THP-1 cells(IC50=<0.5 µM).	price>
R-R-2897	Lysipressin acetate CAS No.83968-49-4	Lysipressin (Lysine vasopressin) acetate/CAS No.83968-49-4 is antidiuretic hormone that have been found in pigs and some marsupial families. Lysipressin acetate induces contraction of the rabbit urinary bladder smooth muscle, activate adenylate-cyclase.	price>
R-C-1198	SW-033291 CAS：459147-39-8	SW033291 is a potent and high-affinity inhibitor of 15-PGDH with a Ki of 0.1 nM.SW033291 increases prostaglandin PGE2 levels in bone marrow and other tissues. SW033291 also promotes tissue regeneration.	price>
R-R-2898	9-Cyclopentyladenine monomethanesulfonate CAS No.189639-09-6	9-Cyclopentyladenine monomethylsulfonate (9-CP-Ade mesylate)/CAS No.189639-09-6 is a stable non-competitive adenylate cyclase inhibitor with cell permeable properties.	price>
R-C-1199	IBET762(GSK525762A) CAS ：1260907-17-2	Molibresib(I-BET-762,GSK525762,GSK525762A)is an inhibitor for BET proteins with IC50 of ~35 nM in a cell-free assay,suppresses the production of proinflammatory proteins by macrophages and blocks acute inflammation,highly selective over other bromodomain-containing proteins.	price>
R-R-2899	Zelminemab CAS No.2225850-33-7	Zelminemab (AMG-301)/CAS No.2225850-33-7 is a human monoclonal antibody that inhibits PACAP type I (PAC1) receptor.	price>
R-C-1200	GSK923295 Cytoskeletal Signaling	GSK-923295 is a special,allosteric inhibitor of centromere-associated protein-E (CENP-E)kinesin motor ATPase activity,with Ki of 3.2±0.2 nM and 1.6± 0.1 nM for human and canine,respectively.	price>
R-R-2900	CB-7921220 CAS No.115453-99-1	CB-7921220/CAS No.115453-99-1 is an adenylate cyclase inhibitor.	price>
R-C-1201	JZL-195 CAS:1210004-12-8	JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor with IC50 of 13 nM and 19 nM for mouse brain FAAH and MAGL respectively.	price>
R-R-2901	NB001 CAS No.686301-48-4	NB001 (HTS 09836)/CAS No.686301-48-4 is an adenylcyclase 1 (AC1) inhibitor which has effect on neural and non-neural pain by modulating AC1 activity.	price>
R-C-1202	MMAE CAS:474645-27-7	Dolastatin 10 is a natural antimitotic and antineoplastic agent that binds to tubulin and inhibits tubulin polymerization.1 Monomethyl Auristatin E(MMAE) is a synthetic analog of dolastatin 10 that similarly inhibits tubulin polymerization and exhibits potent cytotoxicity.It is commonly conjugated with monoclonal antibodies directed at antigens specific to cancer cells for tumor-directed cytotoxicity.2,3 MMAE is typically coupled to the antibody via a protease-cleavable linker,allowing separation of the drug from the antibody following intracellular localization.	price>
R-R-2902	Adenylyl cyclase type 2 agonist-1 CAS No.2414908-52-2	Adenylyl cyclase type 2 agonist-1 (Compound 73)/CAS No.2414908-52-2 is a potent agonist of adenylyl cyclase type 2 (AC2) with the EC50 of 90 nM. Adenylyl cyclase type 2 agonist-1 inhibits expression of Interleukin-6, making it a potential lead compound against respiratory diseases.	price>
R-C-1203	STF-31 CAS:724741-75-7	Glucose transporter 1(Glut1)is an inducible carrier of pentoses and hexoses, including glucose.STF-31 is an inhibitor of Glut1(IC50=~1 µM)that blocks glucose uptake.It induces necrosis in cancer cells that lack the von Hippel-Lindau tumor suppressor gene,which overexpress Glut1.1 Although STF-31 binds Glut1, suggesting a direct effect,STF-31 also inhibits nicotinamide phosphoribosyltransferase,an enzyme that induces Glut1 expression.STF-31 is also toxic to human pluripotent stem cells(hPSCs)and can be used to selectively eliminate hPSCs from mixed cultures.	price>
R-R-2903	Small Cardioactive Peptide B (SCPB) CAS No.84746-43-0	Small Cardioactive Peptide B (SCPB)/CAS No.84746-43-0, a neurally active peptide, stimulates adenylate cyclase activity in particulate fractions of both heart and gill tissues with EC50s of 0.1 and 1.0 μM, respectively.	price>
R-C-1204	Ostarine(MK2286) CAS:841205-47-8	Ostarine(GTx-024,MK-2866)is a selective androgen receptor modulator (SARM)with Ki of 3.8 nM,and is tissue-selective for anabolic organs.	price>
R-R-2904	Albanin A CAS No.73343-42-7	Albanin A/CAS No.73343-42-7, a flavonoid, suppresses glutamate release by decreasing Ca2+/calmodulin/adenylate Cyclase 1 (AC1) activation in synaptosomes and exerts neuroprotective effect in vivo. Albanin A has anti-inflflammatory activity.	price>
R-C-1205	Glycochenodeoxycholic acid CAS:640-79-9	Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) induces hepatocyte apoptosis.	price>

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