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Catalog	name	Description	price
R-R-3037	ARS-1630 CAS No.1698055-86-5	ARS-1630/CAS No.1698055-86-5, a less active enantiomer of ARS-1620, is a novel inhibitor of mutant K-ras G12C extracted from patent WO 2015054572 A1.	price>
R-C-6457	POLY(4-VINYL PYRIDINE-CO-2-HYDROXYETHYL METHACRYLATE), RANDOM	Poly(4-vinyl pyridine-co-2-hydroxyethyl methacrylate)is a random copolymer composed of 4-vinyl pyridine and 2-hydroxyethyl methacrylate units.The 4-vinyl pyridine units introduce cationic and basic properties to the copolymer,while the 2-hydroxyethyl methacrylate units contribute hydrophilic and potentially hydrogen bonding functionalities.	price>
R-C-1338	BMS833923 CAS：1059734-66-5	BMS-833923(XL-139)is an orally bioavailable small-molecule inhibitor of Smoothened with potential antineoplastic activityinhibits BODIPY cyclopamine binding to SMO in a dose-dependent manner with an IC50 of 21 nM.	price>
R-R-3038	KRAS inhibitor-10 CAS No.2578876-75-0	KRAS inhibitor-10 (compound 11)/CAS No.2578876-75-0 selectively and effectively inhibit RAS proteins, and particularly KRAS proteins. KRAS inhibitor-10 is an orally active anti-cancer agent and can be used for cancer research, such as pancreatic cancer, breast cancer, multiple myeloma, leukemia and lung cancer. KRAS inhibitor-10 is a tetrahydroisoquinoline compound (compound 11) extracted from patent WO2021005165 A1.	price>
R-C-6458	POLY(VINYL ALCOHOL-CO-ACRYLIC ACID),RANDOM	Poly(vinyl alcohol-co-acrylic acid),RANDOM refers to a copolymer created from two different monomers: vinyl alcohol and acrylic acid.PVA is a synthetic polymer that is known for its water solubility,as well as its good film-forming,emulsifying,and adhesive properties.PVA is also biodegradable and non-toxic.The specific properties of the copolymer will depend on the ratio of vinyl alcohol to acrylic acid, the degree of the polymerization,and the molecular weight of the resulting polymer.	price>
R-C-1339	NU2058 CAS：161058-83-9	NU2058(O(6)-Cyclohexylmethylguanine)is an inhibitor of CDK2 with IC50 value of 17 μM in an isolated enzyme assay.It also potentiates melphalan(DMF 2.3),and monohydroxymelphalan(1.7),but not temozolomide or ionising radiation.	price>
R-R-3039	KRAS G12C inhibitor 15 CAS No.2349393-21-9	KRAS G12C inhibitor 15/CAS No.2349393-21-9 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 22, has an IC50 of 5 nM.	price>
R-C-6459	POLY(4-[TERT-BUTOXYCARBONYLOXY]-STYRENE-CO-4-ACETOXYSTYRENE),RANDOM	Poly(4-[tert-butoxycarbonyloxy]-styrene-co-4-acetoxystyrene) is a random copolymer consisting of 4-[tert-butoxycarbonyloxy]-styrene and 4-acetoxystyrene units. This copolymer is designed to possess a combination of properties derived from both monomer units.	price>
R-C-1340	SB202190 (FHPI) CAS：152121-30-7	SB202190(FHPI)is a potent p38 MAPK inhibitor targeting p38α/β with IC50 of 50 nM/100 nM in cell-free assays,sometimes used instead of SB 203580 to investigate potential roles for SAPK2a/p38 in vivo.SB202190 inhibits endothelial cell apoptosis via induction of autophagy and heme oxygenase-1.SB202190 significantly suppresses Erastin‐dependent ferroptosis.	price>
R-R-3040	APS6-45 CAS No.2188236-41-9	APS6-45/CAS No.2188236-41-9 is an orally active tumor-calibrated inhibitor (TCI). APS6-45 inhibits RAS/MAPK signaling and exhibits antitumor activity.	price>
R-C-6460	p-Nitrophenylacetonitrile CAS：555-21-5	4-Nitrophenylacetonitrile,4-Nitrophenylacetonitrile is used as a radical inhibitor in the polymerization of vinyl acetate.Our company can provide large-sized,KG grade products.	price>
R-C-1341	PHA-767491HCL CAS：942425-68-5	PHA-767491,also known as CAY10572,is a potent,ATP-competitive dual cdc7/cdk9 inhibitor(IC50 values are 10 and 34 nM respectively)that prevents initiation of DNA replication.PHA-767491 Suppresses Hepatocarcinoma Synergistically with 5-Fluorouracil.PHA-767491 in combination with 5-FU exhibited much stronger cytotoxicity and induced significant apoptosis manifested by remarkably increased caspase 3 activation and poly(ADP-Ribose)polymerase fragmentation in HCC cells.	price>
R-R-3041	MRTF/SRF-IN-1 CAS No.1922098-90-5	MRTF/SRF-IN-1 (example 41)/CAS No.1922098-90-5 is an inhibitor of both myocardin-related transcription factor and serum response factor (MRTF/SRF). MRTF/SRF-IN-1 can be used for research for preventing cancer and fibrosis.	price>
R-C-1342	Epacadostat (INCB024360) CAS：1204669-58-8	Epacadostat,also known as INCB024360 or INCB24360,is an orally available hydroxyamidine and inhibitor of indoleamine 2,3-dioxygenase(IDO1)with potential immunomodulating and antineoplastic activities.INCB024360 targets and binds to IDO1,an enzyme responsible for the oxidation of tryptophan into kynurenine.By inhibiting IDO1 and decreasing kynurenine in tumor cells,INCB024360 increases and restores the proliferation and activation of various immune cells,including dendritic cells(DCs),NK cells,and T-lymphocytes,as well as interferon(IFN)production,and a reduction in tumor-associated regulatory T cells (Tregs).	price>
R-R-3042	SOS1 activator 1 CAS No.2245237-53-8	SOS1 activator 1 (Compound 64)/CAS No.2245237-53-8 is a potent activator of SOS1-mediated nucleotide exchange with a Kd of 44 nM. SOS1 is a guanine nucleotide exchange factor that catalyzes the exchange of GDP for GTP on RAS.	price>
R-C-1343	GLYX13 CAS：117928-94-6	Rapastinel,also known as GLYX-13 and BV-102,It is a centrally active, intravenously administered(non-orally active)amidated tetrapeptide(Thr-Pro-Pro-Thr-NH2)that acts as a selective,weak partial agonist(mixed antagonist/agonist) of an allosteric site at the glycine site of the NMDA receptor complex (Emax≈25%).	price>
R-R-3043	Oncrasin-1 CAS No.75629-57-1	Oncrasin-1/CAS No.75629-57-1 is a potent and effective anticancer inhibitor that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations; also led to abnormal aggregation of PKCι in nucleus of sensitive cells but not in resistant cells.	price>
R-C-1344	Ezetimibe (SCH-58235） CAS：163222-33-1	Ezetimibe,also known as SCH 58235,is a drug that lowers plasma cholesterol levels.It acts by decreasing cholesterol absorption in the small intestine.It may be used alone when other cholesterol-lowering medications are not tolerated, or together with statins(ezetimibe/simvastatin)when statins alone do not control cholesterol.	price>
R-R-3044	PROTAC SOS1 degrader-1 TFA	PROTAC SOS1 degrader-1 (TFA) is a potent PROTAC SOS1 degrader with an DC50 of 98.4 nM. PROTAC SOS1 degrader-1 shows antiproliferation activity in cancer cells with various KRAS mutations. PROTAC SOS1 degrader-1 shows antitumor effect with low toxicity.	price>
R-C-1345	Eliprodil (SL-820715） CAS：119431-25-3	Eliprodil,aslo known as SL-82,0715;is a NMDA antagonist.NMDA receptors are a key component in mediating glutamate-induced excitotoxicity,and it is believed that NMDA antagonists would be neuroprotective after a stroke or other traumatic brain injury.Eliprodil protects pyramidal neurons in hippocampal slices from hypoxic/ischemic damage.Eliprodil stimulates CNS myelination,may be a new prospect for multiple sclerosis.	price>

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