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R-C-1334 MSX122 CAS:897657-95-3 MSX-122 is an orally bioavailable inhibitor of CXCR4(IC50=10 nM)with potential antineoplastic and antiviral activities.CXCR4 inhibitor MSX-122 binds to the chemokine receptor CXCR4,preventing the binding of stromal derived factor-1 (SDF-1)to the CXCR4 receptor and receptor activation,which may result in decreased tumor cell proliferation and migration. price>
R-R-3034 RMC-4998 CAS No.2642037-07-6 RMC-4998/CAS No.2642037-07-6 is a molecular glue compound with good antitumor activity. RMC-4998 is able to form a ternary complex with CYPA and an activated KRAS G12C mutant. Furthermore, CYPA binding to KRAS G12C blocks the interaction between activated KRAS mutants and downstream effector proteins, thereby inhibiting signaling that promotes cell proliferation. price>
R-C-8034 Methacrylate based nickel ion imprinted polymers Methacrylate based nickel ion imprinted polymer,Methacrylic acid based nickel ion imprinted polymer is a highly selective functional polymer material prepared by ion imprinting technology with methacrylic acid as the core functional monomer and Ni2 as the template ion.It is also known as artificial nickel ion antibody and is widely used in fields such as biomedical materials and environmental analysis.This product is only for scientific research and cannot be used on the human body. price>
R-C-1335 XY1 CAS:1624117-53-8 XY1 is a close analog of SGC707 that is completely inactive against PRMT3 at concentrations as high as 100 µM.SGC707 is a potent,selective allosteric inhibitor of PRMT3(IC50=50nM).It inhibits the methylation of histones in cells with an IC50 value below 1 µM. price>
R-R-3035 6H05 TFA CAS No.2061344-88-3 6H05 TFA/CAS No.2061344-88-3 is a selective, and allosteric inhibitor of oncogenic mutant K-Ras(G12C). price>
R-C-8035 PVL14k Polyvalerolactone, also known as Polyvalerolactone (PVL), is a biodegradable polyester obtained by ring opening polymerization of delta valerolactone. It has been extensively studied in the fields of drug delivery and biomedical materials.This product is only for scientific research and cannot be used on the human body. price>
R-C-1336 PS-1145 CAS:431898-65-6 PS-1145 is a selective IκB kinase(IKK)inhibitor(IC50100 nM).PS1145 efficiently inhibited both basal and induced NF-kappaB activity in PC cells.PS1145 induced caspase 3/7-dependent apoptosis in PC cells and significantly sensitized PC cells to apoptosis induced by tumor necrosis factor alpha.PS1145 inhibited PC cell proliferation.PS1145 enhances apoptosis in DMBA-induced tumor in male Wistar rats. price>
R-R-3036 Nexinhib20 CAS No.331949-35-0 Nexinhib20/CAS No.331949-35-0 is a specific Rab27a-JFC1 interaction inhibitor with a calculated IC50 of 2.6 μM. Nexinhib20 significantly inhibits superoxide anion production. Nexinhib20 efficiently decreases exocytosis of azurophilic granules in neutrophils stimulated with fMLP, GM-CSF or both. Nexinhib20 has a significant anti-inflammatory activity. price>
R-C-8036 D-sphingosine liposome D-sphingosine liposome usually refers to a liposome preparation or liposome research system containing D-sphingosine(D-sphingosine).D-sphingosine is a sphingolipid related molecule with a long-chain hydrophobic structure and polar amino and hydroxyl groups,which can participate in cell membrane lipid metabolism and cell signal regulation.This product is only for scientific research and cannot be used on the human body. price>
R-C-1337 FPH2(BRD9424) CAS:957485-64-2 FPH2(BRD-9424)is an inducer of proliferation of primary human hepatocytes.In vitro,FPH2 induced functional proliferation of hepatocytes and might be useful for expanding mature human primary hepatocytes.FPH2(40μM)increased the area of hepatocyte colonies with more hepatocytes and Ki67-positive nuclei,which exhibited hepatocyte nuclear morphologies.In primary human hepatocytes from six additional cell sources,FPH2 increased hepatocytes expansion.FPH2 increased hepatocyte at a rate that is consistent with liver regeneration kinetics in vivo . price>
R-R-3037 ARS-1630 CAS No.1698055-86-5 ARS-1630/CAS No.1698055-86-5, a less active enantiomer of ARS-1620, is a novel inhibitor of mutant K-ras G12C extracted from patent WO 2015054572 A1. price>
R-C-6457 POLY(4-VINYL PYRIDINE-CO-2-HYDROXYETHYL METHACRYLATE), RANDOM Poly(4-vinyl pyridine-co-2-hydroxyethyl methacrylate)is a random copolymer composed of 4-vinyl pyridine and 2-hydroxyethyl methacrylate units.The 4-vinyl pyridine units introduce cationic and basic properties to the copolymer,while the 2-hydroxyethyl methacrylate units contribute hydrophilic and potentially hydrogen bonding functionalities. price>
R-C-8037 MurNAc(CAS:10597-89-4) MurNAc(CAS:10597-89-4),also known as N-acetyl murate,is a core monosaccharide unit unique to the peptidoglycan backbone of bacterial cell walls.It is a lactate ether derivative of N-acetylglucosamine,and the C3 position of the glucose backbone is connected to a D-lactate group through an ether bond.This site can further covalently bind to the tetrapeptide side chain and is the core anchor point of the peptidoglycan network cross-linking structure.This product is only for scientific research and cannot be used on the human body. price>
R-C-1338 BMS833923 CAS:1059734-66-5 BMS-833923(XL-139)is an orally bioavailable small-molecule inhibitor of Smoothened with potential antineoplastic activityinhibits BODIPY cyclopamine binding to SMO in a dose-dependent manner with an IC50 of 21 nM. price>
R-R-3038 KRAS inhibitor-10 CAS No.2578876-75-0 KRAS inhibitor-10 (compound 11)/CAS No.2578876-75-0 selectively and effectively inhibit RAS proteins, and particularly KRAS proteins. KRAS inhibitor-10 is an orally active anti-cancer agent and can be used for cancer research, such as pancreatic cancer, breast cancer, multiple myeloma, leukemia and lung cancer. KRAS inhibitor-10 is a tetrahydroisoquinoline compound (compound 11) extracted from patent WO2021005165 A1. price>
R-C-6458 POLY(VINYL ALCOHOL-CO-ACRYLIC ACID),RANDOM Poly(vinyl alcohol-co-acrylic acid),RANDOM refers to a copolymer created from two different monomers: vinyl alcohol and acrylic acid.PVA is a synthetic polymer that is known for its water solubility,as well as its good film-forming,emulsifying,and adhesive properties.PVA is also biodegradable and non-toxic.The specific properties of the copolymer will depend on the ratio of vinyl alcohol to acrylic acid, the degree of the polymerization,and the molecular weight of the resulting polymer. price>
R-C-8038 Hyaluronate Decasaccharide CAS:57282-62-9 Hyaluronate Decasacharide (CAS:57282-62-9), also known as Hyaluronic Acid Decase,It is a low molecular weight oligosaccharide obtained by enzymatic or chemical degradation of hyaluronic acid. It is composed of five repeated D-glucuronic acid and N-acetylglucosamine disaccharide units alternately connected, and is a core research reagent in the field of targeted delivery of biomaterials and tumors.This product is only for scientific research and cannot be used on the human body. price>
R-C-1339 NU2058 CAS:161058-83-9 NU2058(O(6)-Cyclohexylmethylguanine)is an inhibitor of CDK2 with IC50 value of 17 μM in an isolated enzyme assay.It also potentiates melphalan(DMF 2.3),and monohydroxymelphalan(1.7),but not temozolomide or ionising radiation. price>
R-R-3039 KRAS G12C inhibitor 15 CAS No.2349393-21-9 KRAS G12C inhibitor 15/CAS No.2349393-21-9 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 22, has an IC50 of 5 nM. price>
R-C-6459 POLY(4-[TERT-BUTOXYCARBONYLOXY]-STYRENE-CO-4-ACETOXYSTYRENE),RANDOM Poly(4-[tert-butoxycarbonyloxy]-styrene-co-4-acetoxystyrene) is a random copolymer consisting of 4-[tert-butoxycarbonyloxy]-styrene and 4-acetoxystyrene units. This copolymer is designed to possess a combination of properties derived from both monomer units. price>