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Catalog	name	Description	price
R-C-1406	PP1 CAS: 172889-26-8	PP1 is a potent inhibitor of Src-family tyrosine kinases.Inhibits p56lck and p59fynT(IC50 values are 5 and 6 nM respectively).Display>8000-fold selectivity over ZAP-70 and JAK2.Also moderately inhibits p38,CSK,PDGF receptors,RET-derived oncoproteins,c-Kit and Bcr-Abl.	price>
R-M-G05	NiO-Al2O3 aerogel	NiO-Al2O3 aerogel/Nickel Oxide-Alumina aerogel from ruixi. NiO-Al2O3 aerogel is a composite material consisting of nickel oxide (NiO) and alumina (Al2O3) in an aerogel form. This material combines the properties of both components and can exhibit enhanced properties such as high surface area, porosity, and potentially catalytic or adsorptive behavior, making it useful in applications such as catalysis, gas sensing, and energy storage.	price>
R-C-1407	1-NA-PP1 CAS:221243-82-9	1-NA-PP1 is a selective inhibitor of v-Src and c-Fyn as well as c-Abl.	price>
R-M-G06	Alumina/Titanium Dioxide Composite Aerogel	Alumina/Titanium Dioxide Composite Aerogel/Al2O3/Ti Dioxide Composite Aerogel from ruixi. Alumina/Titanium Dioxide Composite Aerogel refers to a material created by combining alumina and titanium dioxide into an aerogel form. This composite can possess advantageous properties such as lightweight structure, high surface area, and potential applications in areas like catalysis, pollution remediation, and energy storage.	price>
R-C-1408	1-NM-PP1 CAS:221244-14-0	1-NM-PP1,a cell-permeable PP1 analog,is a potent Src family kinases inhibitor with IC50s of 4.3nM and 3.2nM for v-Src-as1 and c-Fyn-as1,respectively.	price>
R-M-G07	Binary Wet Gel	Binary wet gel composed of nickel nitrate and aluminum isopropoxide as raw materials is a precursor material used in the production of various nanostructured materials such as metal oxides, catalysts, and functional coatings. This gel is often utilized in the sol-gel process for creating advanced composite materials with specific properties tailored for diverse applications in fields like catalysis, sensors, and optics.	price>
R-C-1409	BML-277 CAS:516480-79-8	Chk2 Inhibitor II(BML-277)is an ATP-competitive inhibitor of Chk2 with IC50 of 15 nM.It is 1000-fold more selective toward Chk2 serine/threonine kinase than for Chk1 and Cdk1/B kinases.Chk2 Inhibitor II(BML-277)dose dependently protects human CD4(+)and CD8(+)T-cells from apoptosis due to ionizing radiation.	price>
R-R-3109	Sumatriptan succinate CAS No.103628-48-4	Sumatriptan succinate (GR 43175)/CAS No.103628-48-4 is an orally active 5-HT1 receptor agonist with IC50s of 7.3 nm, 9.3nm and 17.8 nm for 5-HT1D, 5-HT1B and 5-HT1F receptors, respectively. Sumatriptan succinate can be used for migraine headache research.	price>
R-C-1410	CZC-25146 CAS:1191911-26-8	CZC-25146 is a second generation inhibitor of LRRK2 with excellent potency and selectivity.In a time-resolved fluorescence resonance energy transfer assay, CZC-25146 shows potent inhibition of both recombinant human wild type LRRK2 and G2019S mutant LRRK2 with IC50 values of 4.76nM and 6.87nM,respectively.CZC-25146 is selective against LRRK2.When treated with 184 different protein kinases and one lipid kinase,CZC-25146 inhibits only five of them with high potency including PLK4,GAK,TNK1,CAMKK2 and PIP4K2C.	price>
R-R-3110	Ziprasidone CAS No.146939-27-7	Ziprasidone (CP-88059)/CAS No.146939-27-7, an orally active antipsychotic agent, is a combined 5-HT and dopamine receptor antagonist. Ziprasidone mesylate trihydrate has affinities for Rat D2 (Ki=4.8 nM), 5-HT2A (Ki=0.42 nM) and 5-HT1A (Ki=3.4 nM).	price>
R-C-1411	ML-365 CAS:947914-18-3	ML365 is a selective two-pore domain potassium channel KCNK3/TASK1 inhibitor, with an IC50 of 4 nM.ML365 acts as a pharmacological tool that can be used to examine the specific roles of TASK1 channels.	price>
R-R-3111	Metergoline CAS No.17692-51-2	Metergoline/CAS No.17692-51-2 is a serotonin (5-HT) receptor and dopamine receptors antagonist, with pKis of 8.64, 8.75 and 8.75 for 5-HT2A, 5-HT2B and 5-HT2C, respectively. Metergoline is a high-affinity ligand for the h5-HT7 receptor, with a Ki of 16 nM. Metergoline is also a reversible neural Na+ channels inhibitor. Metergoline is commonly used for the research of seasonal affective disorder, prolactin hormone regulation.	price>
R-C-1412	CHIR-98014 CAS:252935-94-7	CHIR-98014 is a potent,cell-permeable GSK-3 inhibitor with IC50s of 0.65 and 0.58 nM for GSK-3α and GSK-3β,respectively;it shows less potent activities against cdc2 and erk2.	price>
R-R-3112	Spiperone CAS No.749-02-0	Spiperone/CAS No.749-02-0 is a potent dopamine D2, serotonin 5-HT1A, and serotonin 5-HT2A antagonist. Spiperone is a widely used pharmacological tool. Spiperone has the potential for the research of neurology diseases.	price>
R-C-1413	G-749 CAS:1457983-28-6	G-749 is a novel FLT3 inhibitor that showed potent and sustained inhibition of the FLT3 wild type and mutants including FLT3-ITD,FLT3-D835Y,FLT3-ITD/N676D,and FLT3-ITD/F691L in cellular assays.G-749 retained its inhibitory potency in various drug-resistance milieus such as patient plasma,FLT3 ligand surge,and stromal protection.	price>
R-R-3113	Mirtazapine CAS No.85650-52-8	Mirtazapine (Org3770)/CAS No.85650-52-8 is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. Mirtazapine is also a 5-HT2, 5-HT3, histamine H1 receptor and α2-adrenoceptor antagonist with pKi values of 8.05, 8.1, 9.3 and 6.95, respectively.	price>
R-C-1414	Pyridostain CAS:1085412-37-8	Pyridostatin(RR82)is a G-quadruplex DNA stabilizing agent(Kd=490 nM). Pyridostatin promotes growth arrest in human cancer cells by inducing replication-and transcription-dependent DNA damage.Pyridostatin targets the proto-oncogene Src.Pyridostatin reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells.	price>
R-R-3114	Ketanserin tartrate CAS No.83846-83-7	Ketanserin (R41468) tartrate/CAS No.83846-83-7 is a selective 5-HT2 receptor antagonist. Ketanserin tartrate also blocks hERG current (IhERG) in a concentration-dependent manner (IC50=0.11 μM).	price>
R-C-1415	KPT330 CAS:1393477-72-9	KPT-330 inhibitor of CRM1(XPO1)-mediated nuclear export has selective anti-leukaemic activity in preclinical models of T-cell acute lymphoblastic leukaemia and acute myeloid leukaemia.	price>
R-R-3115	Pimavanserin hemitartrate CAS No.706782-28-7	Pimavanserin (ACP-103) hemitartrate/CAS No.706782-28-7 is a potent 5-HT 2A receptor inverse agonist with pIC50 and pKi of 8.73 and 9.3, respectively.	price>

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