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Catalog	name	Description	price
R-C-1487	Pazopanib (GW786034) CAS：444731-52-6	Pazopanib(GW786034)is a novel multi-target inhibitor of VEGFR1,VEGFR2,VEGFR3,PDGFRβ,c-Kit,FGFR1,and c-Fms with IC50s of 10,30,47, 84,74,140 and 146 nM,respectively.	price>
R-R-3187	Dolasetron CAS No.115956-12-2	Dolasetron(MDL-73147)/CAS No.115956-12-2 is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy.	price>
R-C-1488	U0126-EtOH CAS：1173097-76-1	U0126-EtOH is a highly selective inhibitor of MEK1/2 with IC50 of 0.07 μM/0.06 μM in cell-free assays,100-fold higher affinity for N3-S218E/S222D MEK than PD98059.U0126 inhibits autophagy and mitophagy with antiviral activity.	price>
R-R-3188	Tandospirone citrate CAS No.112457-95-1	Tandospirone citrate/CAS No.112457-95-1 is a potent and selective 5-HT1A receptor partial agonist (Ki = 27 nM) that displays selectivity over SR-2, SR-1C, α1, α2, D1 and D2 receptors (Ki values ranging from 1300-41000 nM).	price>
R-C-1489	Fulvestrant (ICI-182780) CAS：129453-61-8	Fulvestrant(ICI-182780,ZD 9238,ZM 182780)is an estrogen recepto(ER)antagonist with IC50 of 0.94 nM in a cell-free assay.Fulvestrant also induces autophagy and apoptosis and has antitumor activity.	price>
R-R-3189	Tropisetron Hydrochloride CAS No.105826-92-4	Tropisetron Hydrochloride (SDZ-ICS-930)/CAS No.105826-92-4 is a selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.	price>
R-C-1490	Decitabine (NSC 127716) CAS：2353-33-5	Decitabine(NSC 127716,Deoxycytidine,Dacogen,5-aza-2-deoxycytidine,5-AZA-dC, 5-aza-CdR)is a DNA methyltransferase inhibitor,incorporating into DNA and resulting in hypomethylation of DNA and intra-S-phase arrest of DNA replication. It is used to treat myelodysplastic syndrome(MDS).Decitabine induces cell cycle arrest and apoptosis in various cancer cell lines.	price>
R-R-3190	Nelotanserin CAS No.839713-36-9	Nelotanserin/CAS No.839713-36-9 is a potent 5-HT2A inverse agonist, a moderately potent 5-HT2C partial inverse agonist and a weak 5-HT2B inverse agonist, with IC50s of 1.7, 79, 791 nM in IP accumulation assays, respectively.	price>
R-R-3191	Pumosetrag Hydrochloride CAS No.194093-42-0	Pumosetrag Hydrochloride (MKC-733; DDP-733)/CAS No.194093-42-0 is an orally available 5-HT3 partial agonist developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.	price>
R-C-1492	Bicalutamide (ICI-176334) CAS：90357-06-5	Bicalutamide is a synthetic,nonsteroidal antiandrogen.Bicalutamide competitively binds to cytosolic androgen receptors in target tissues,thereby inhibiting the receptor binding of androgens.This agent does not bind to most mutated forms of androgen receptors.	price>
R-R-3192	Befiradol hydrochloride CAS No.2436760-81-3	Befiradol hydrochloride (NLX-112 hydrochloride)/CAS No.2436760-81-3 is a selective 5-HT1A receptor agonist.	price>
R-C-1493	Letrozole (CGS 20267) CAS:112809-51-5	Letrozole(CGS 20267)is a third generation inhibitor of aromatase with IC50 of 0.07-20 nM in cell-free assays.It has no effect on the plasma levels of 17α-OH progesterone,thyroid-stimulating hormone(TSH),luteinizing hormone(LH),follicle-stimulating hormone(FSH),or androstenedione and does not affect normal urine electrolyte excretion or thyroid function in clinical studies.Letrozole induces autophagy.	price>
R-R-3193	Xaliproden hydrochloride CAS No.90494-79-4	Xaliproden hydrochloride (SR57746A)/CAS No.90494-79-4 is a potent, selective and orally active agonist of 5-HT1A receptor, shows a high affinity for 5-HT1A specific binding sites in the rat hippocampus (IC50=3 nM). Xaliproden hydrochloride is also a selective antagonist of dopamine D2 receptor, has moderate affinity (IC50=0.1-1 μM). Xaliproden hydrochloride exhibits anti-depression and anti-anxiety effects, and it may possess therapeutic potential for the research of neurodegenerative diseases.	price>
R-C-1494	Enalaprilat Dihydrate CAS: 84680-54-6	Enalaprilat is the active metabolite of enalapril.It is the first dicarboxylate-containing ACE inhibitor and was developed partly to overcome these limitations of captopril.	price>
R-R-3194	GR 125743 CAS No.148547-33-5	GR 125743/CAS No.148547-33-5 is a selective 5-HT1B/1D receptor antagonist, with pKis of 8.85 and 8.31 for wild-type h5-HT1B and wild-type h5-HT1D, respectively.	price>
R-C-1495	Daptomycin CAS:103060-53-3	Daptomycin is a lipopeptide antibiotic used in the treatment of certain infections caused by Gram-positive organisms.	price>
R-R-3195	Ecopipam hydrochloride CAS No.190133-94-9	Ecopipam (SCH 39166) hydrochloride/CAS No.190133-94-9 is a potent, selective and orally active antagonist of dopamine D1/D5 receptor, with Kis of 1.2 nM and 2.0 nM, respectively. Ecopipam hydrochloride shows more than 40-flod selectivity over D2, D4, 5-HT, and α2a receptor (Ki=0.98, 5.52, 0.08, and 0.73 μM, respectively). Ecopipam hydrochloride can be used for the research of schizophrenia and obesity.	price>
R-C-1496	BI-78D3 CAS:883065-90-5	BI-78D3(JNK Inhibitor X),is a potent JNK inhibitor.BI-78D3 dose-dependently inhibits the phosphorylation of JNK substrates both in vitro and in cell.BI-78D3 not only blocks JNK dependent Con A-induced liver damage but also restores insulin sensitivity in mouse models of type 2 diabetes.	price>
R-R-3196	A-582941 dihydrochloride CAS No.848591-90-2	A-582941 dihydrochloride/CAS No.848591-90-2 is a potent, selective and brain-penetrant partial agonist of α7 nAChR, with Kis of 10.8 and 16.7 nM in rat brain membranes and human frontal cortex, respectively. A-582941 dihydrochloride also binds to human 5-HT3 receptor with a Ki of 150 nM. A-582941 has the potential for cognitive deficits associated with various neurodegenerative and psychiatric disorders research.	price>
R-C-1497	SKF96365 CAS:130495-35-1	SKF96365,originally identified as a blocker of receptor-mediated calcium entry, is widely used diagnostically,as a blocker of transient receptor potential canonical type(TRPC)channels.	price>

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