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Catalog	name	Description	price
R-R-3247	Hypidone hydrochloride CAS No.1339058-04-6	Hypidone hydrochloride (YL0919)/CAS No.1339058-04-6 is an orally active antidepressant agent with dual activity as a highly seletive 5-HT uptake blocker and an effective 5-HT1A receptor agonist (Ki=0.19 nM). Hypidone hydrochloride inhibits the uptake of [3H]-5-HT into rat cerebral cortical synaptosomes and HEK293 cells with IC50s of 1.78 nM and 1.93 nM, respectively. Hypidone hydrochloride shows remarkable antidepressant effects in animal models and has the poential for the investigation of depressive disorder.	price>
R-C-1548	Voruciclib CAS :1000023-04-0	Voruciclib is a flavone and cyclin dependent kinase(CDK)inhibitor with potential antineoplastic activity.	price>
R-R-3248	Myristicin CAS No.607-91-0	Myristicine/CAS No.607-91-0 is an orally bioavailable serotonin receptor antagonist and weak monoamine oxidase (MAO) inhibitor. Myristicine also exerts anti-cancer effects on gastric cancer cells by inhibiting the EGFR/ERK signaling pathway. Myristicine is the main component of nutmeg essential oil and has anti-cancer, anti-proliferative, antibacterial, anti-inflammatory and apoptosis-inducing effects. Myristicine abuse can produce hallucinogenic effects, organ damage, etc.	price>
R-C-1549	Eganelisib (IPI-549) CAS:1693758-51-8	Eganelisib(IPI549)is a potent and selective PI3Kγ inhibitor with an IC50 of 16 nM.Eganelisib shows>100-fold selectivity over other lipid and protein kinases.	price>
R-R-3249	LY266097 hydrochloride CAS No.172895-39-5	LY266097 hydrochloride/CAS No.172895-39-5 is a selective 5-HT2B receptor antagonist with pKis of 7.7, 9.8, and 7.6 for 5-HT2A, 5-HT2B, 5-HT2C, respectively. 5-HT2B receptor blockade contributes to the research in depression.	price>
R-C-1550	LY-3177833 CAS:1627696-51-8	LY-3177833 is a potent and selective inhibitor of CDC7(Cell Division Cycle 7-related Protein Kinase).	price>
R-R-3250	Norfluoxetine hydrochloride CAS No.57226-68-3	Norfluoxetine hydrochloride/CAS No.57226-68-3 is an active N-demethylated metabolite of Fluoxetine. Fluoxetine is a selective serotonin (5-HT) reuptake inhibitor that is metabolized to Norfluoxetine hydrochloride by cytochrome P450 (CYP) 2D6, CYP2C19, and CYP3A4. Norfluoxetine hydrochloride inhibits 5-HT uptake and inhibits CaV3.3 T current (IC50 = 5 μM). Norfluoxetine hydrochloride has anticonvulsant activity.	price>
R-C-1551	Tubercidin CAS:69-33-0	Tubercidin(7-deaza-adenosine),an adenosine analogue,is a nucleoside antibiotic.It is incorporated into DNA and inhibits polymerases,thereby inhibiting DNA replication and RNA and protein synthesis.This agent also exhibits antifungal and antiviral activities.	price>
R-R-3251	Didesmethyl cariprazine CAS No.839712-25-3	Didesmethyl cariprazine/CAS No.839712-25-3 is a metabolite of Cariprazine and acts as the predominant circulating active moiety. Didesmethyl cariprazine has a long half-life of 1-3 weeks. Cariprazine is a antipsychotic agent candidate that exhibits high affinity for the D3 and D2 receptors, and moderate affinity for the 5-HT1A receptor.	price>
R-C-1552	C646 CAS NO. 328968-36-1	C646 is an inhibitor for histone acetyltransferase,and inhibits p300 with a Ki of 400 nM in a cell-free assay.Preferentially selective for p300 versus other acetyltransferases.C646 induces cell cycle arrest,apoptosis and autophagy.	price>
R-R-3252	SB-616234-A CAS No.908601-49-0	SB-616234-A/CAS No.908601-49-0 is a selective and orally bioavailable 5-HT1B receptor antagonist, with anxiolytic and antidepressant activity.	price>
R-C-1553	Bay 59-3074 CAS:406205-74-1	Bay 59-3074 is a selective cannabinoid CB1/CB2 receptor partial agonist with Ki of 55.4 nM,48.3 nM and 45.5nM at rat and human CB1 and human CB2 receptors, respectively.Bay 59-3074 displays analgesic properties.	price>
R-R-3253	Spiramide CAS No.510-74-7	Spiramide (AMI-193)/CAS No.510-74-7 is a potent and selective antagonist of 5-HT2 and dopamine D2 receptor, with Kis of 2 nM and 3 nM, respectively. Spiramide has >2000-fold selectivity for 5-HT2 versus 5-HT1C (Ki=4300 nM) receptors. Spiramide exhibits antipsychotic activity.	price>
R-C-1554	PNU282987HCL CAS:123464-89-1	PNU282987 is a drug that acts as a potent and selective agonist for the α7 subtype of neural nicotinic acetylcholine receptors.In animal studies,it shows nootropic effects,and derivatives may be useful in the treatment of schizophrenia,although PNU-282,987 is not suitable for use in humans because of excessive inhibition of the hERG antitarget.	price>
R-R-3254	Cerlapirdine CAS No.925448-93-7	Cerlapirdine (SAM-531, PF-05212365)/CAS No.925448-93-7 is a selective and potent full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor.	price>
R-C-1555	shp099 CAS:1801747-42-1	SHP099 is a potent,selective,orally available SHP2 inhibitor with an IC50 of 70 nM.	price>
R-R-3255	Usmarapride CAS No.1428862-33-2	Usmarapride (SUVN-D4010)/CAS No.1428862-33-2 is a potent, selective, orally active and brain penetrant 5-HT4 receptor partial agonist (EC50=44 nM).	price>
R-C-1556	Lirametostat (CPI-1205) CAS:1621862-70-1	Lirametostat (CPI-1205) is an orally available selective inhibitor of the histone lysine methyltransferase EZH2 with IC50 values of 2 nM and 52 nM for EZH2 and EZH1 respectively. It has potential antineoplastic activity.	price>
R-R-3256	Usmarapride free base CAS No.1428862-32-1	Usmarapride (SUVN-D4010) free base/CAS No.1428862-32-1 is a potent, selective, orally active and brain penetrant 5-HT4 receptor partial agonist (EC50=44 nM).	price>
R-C-1557	GNE-493 CAS:1033735-94-2	GNE-493 is a potent,selective,and orally available dual pan-PI3-kinase/mTOR inhibitor with IC50s of 3.4 nM,12 nM,16nM,16 nM and 32 nM for PI3Kα,PI3Kβ,PI3Kδ,PI3Kγ and mTOR.	price>

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