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R-C-1776 PE859 CAS:1402727-29-0 PE859 is a potent inhibitor of both tau and Aβ aggregation with IC50 values of 0.66 and 1.2μM,respectively. price>
R-AC-0030 Hydrated Iron Oxide Chitosan Loaded Graphene Oxide Aerogel Hydrated Iron Oxide Chitosan Loaded Graphene Oxide Aerogel is an advanced material with a unique combination of components. This aerogel consists of graphene oxide, which provides a vast surface area and exceptional mechanical strength, coupled with the porous chitosan matrix, and the functional properties of hydrated iron oxide.The incorporation of hydrated iron oxide into the chitosan-loaded graphene oxide framework offers enhanced magnetic properties and catalytic potential, making it suitable for applications such as environmental remediation, catalysis, and magnetic separations. The presence of chitosan further adds biocompatibility and antimicrobial properties to the aerogel.This composite aerogel presents an intriguing combination of properties, including high porosity, large specific surface area, and unique chemical reactivity, making it a versatile material for applications across various fields, such as environmental science, biomedicine, and catalysis. price>
R-C-1777 Oxamflatin CAS:151720-43-3 Oxamflatin is a potent HDAC inhibitor,inhibiting the growth of mouse and human cancer cell lines. price>
R-R-3477 Ondansetron-d5 CAS No.1219798-86-3 Ondansetron-d5/CAS No.1219798-86-3 is the deuterium labeled Ondansetron. Ondansetron (GR 38032; SN 307) is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy. price>
R-C-1778 A 419259 (trihydrochloride) CAS: 364042-47-7 A 419259 is a broad-spectrum pyrrolo-pyrimidine inhibitor,designed to enhance selectivity towards the Src family with IC50 of 9 nM,<3 nM and<3nM for Src,Lck and Lyn,respectively. price>
R-R-3478 Ziprasidone-d8 CAS No.1126745-58-1 Ziprasidone-d8/CAS No.1126745-58-1 is deuterium labeled Ziprasidone, which is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects of antipsychotic activity. price>
R-C-1779 AN-2718 CAS:174672-06-1 AN2718 is a novel boron-containing small molecule that inhibits an essential protein synthesis enzyme,leucyl-transfer RNA synthetase,or LeuRS. price>
R-R-3479 AP521 CAS No.151227-08-6 AP521/CAS No.151227-08-6 is an agonist of human 5-HT1A receptor with an IC50 of 94 nM. price>
R-C-1780 P22077 CAS:1247819-59-5 P 22077 is a cell-permeable inhibitor of the ubiquitin-specific protease(IC??= 8.6μM)and the closely related deubiquitinase(DUB)USP47. price>
R-R-3480 Vilazodone-d8 CAS No.1794789-93-7 Vilazodone-d8/CAS No.1794789-93-7 is the a deuterium labeled vilazodone, which is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist. price>
R-C-1781 JNJ 42153605 CAS:1254977-87-1 JNJ-42153605 is a potent and selective mGlu2 receptor PAM with an acceptable pharmacokinetic profile in rodent and nonrodent species.JNJ-42153605 showed centrally mediated in vivo effectivity in models sensitive to mGlu2 receptor modulation such as sleep−wake electroencephalogram in rats,34 showing suppressed REM sleep during the first 4 h after oral administration of a 3 mg/kg dose. price>
R-R-3481 H-9 Dihydrochloride CAS No.116700-36-8 H-9 Dihydrochloride/CAS No.116700-36-8 is a PKA (protein kinase) inhibitor. H-9 Dihydrochloride (10 μM) significantly reduces the excitatory response to 5-HT. H-9 Dihydrochloride also has a direct effect on pharyngeal activity. H-9 Dihydrochloride inhibits signal-transduction and cell growth in EGF (epidermal growth factor)-dependent epithelial cell lines. price>
R-C-1782 Ebselen CAS:60940-34-3 Ebselen(SPI-1005)is an inhibitor of HIV-1 capsid CTD dimerization.Ebselen can permeate the blood-brain barrier and inhibit inositol monophosphatase(IMPase). Ebselen is a non-toxic seleno-organic drug with anti-inflammatory and antioxidant properties.Ebselen inhibits QSOX1 enzymatic activity and has anticancer activity. price>
R-R-3482 (S)-Mirtazapine-d3 (S)-Mirtazapine-d3 is a deuterium labeled (S)-Mirtazapine. (S)-Mirtazapine is a S(+)-enantiomer of Mirtazapine with pronociceptive properties in an animal model of acute thermal nociception.(S)-Mirtazapine is a stereoselective 5-HT2 receptor antagonist. (S)-Mirtazapine is metabolized by CYP2D6 and CYP1A2. price>
R-C-1783 Pleconaril(VP 63843,Win 63843) CAS:153168-05-9 Pleconaril(APO-P001,Picovir,VP 63843,WIN 63843)is a capsid inhibitor used previously to treat enterovirus infections.Pleconaril is effective in inhibiting replication with IC50 of<0.050μM. price>
R-R-3483 (S)-WAY 100135 dihydrochloride CAS No.149007-54-5 (S)-WAY 100135 dihydrochloride/CAS No.149007-54-5 is a highly selective and potent antagonist of 5-HT 1A (IC50=33.9 nM). (S)-WAY 100135 dihydrochloride has anxiolytic activity in animal models. price>
R-C-1784 Acumapimod (BCT-197) CAS:836683-15-9 Acumapimod(BCT197)is an orally active p38 MAP kinase inhibitor,with an IC50 of less than 1 μM for p38α. price>
R-R-3484 NEO 376 CAS No.496921-73-4 NEO 376/CAS No.496921-73-4 is a selective modulator of 5-HT1 receptor, GABA receptor and dopamine receptor, with anti-psychotic actively. price>
R-C-1785 SGC2085 CAS:1821908-48-8 SGC2085 is a potent and selective Coactivator Associated Arginine Methyltransferase 1(CARM1)inhibitor with an IC50 value of 50nM and>100-fold selective over other PRMTs. price>
R-R-3485 Nemonapride CAS No.75272-39-8 Nemonapride/CAS No.75272-39-8 is a highly potent dopamine D2 receptor antagonist with a Ki of 0.06 nM. Nemonapride also activates 5-HT1A receptor with an IC50 of 34 nM. Nemonapride is an antipsychotic that readily passes through the blood brain barrier and exhibits potent neuroleptic effects in animals. price>