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Catalog	name	Description	price
R-C-1786	WIKI4 CAS:838818-26-1	WIKI4 is a potent tankyrase inhibitor with an IC50 of 26 nM for TNKS2. WIKI4 potently inhibits Wnt/β-catenin signaling and that its half-maximal response dose is 75 nM.WIKI4 mediates its effects on Wnt/β-catenin signaling by inhibiting the enzymatic activity of TNKS2.WIKI4 is cytotoxic to SCLC cells with an IC50 value of 0.02μM.	price>
R-R-3486	ARC 239 CAS No.67339-62-2	ARC 239/CAS No.67339-62-2 is an α2B/C-adrenergic receptor antagonist with pKi of 7.06 and 6.95 for rat kidney α2B and human α2C, respectively. ARC 239 also inhibits 5-HT1A receptor with a Ki of 63.1 nM.	price>
R-C-1787	VGX-1027 CAS：6501-72-0	VGX-1027 displays immunomodulatory and anti-inflammatory activities by inhibiting toll-like receptor 4(TLR4)signaling.	price>
R-R-3487	7-Desmethyl-agomelatine-d3 CAS No.2749427-92-5	7-Desmethyl-agomelatine-d3/CAS No.2749427-92-5 is a deuterium labeled 7-Desmethyl-agomelatine. 7-Desmethyl-agomelatine is a metabolite of Agomelatine.	price>
R-C-1788	TCS OX2 29 CAS：372523-75-6	TCS-OX2-29 is a potent,high affinities and selective orexin-2 receptor(OX2R) antagonist with an IC50 value of 40nM and a pKI value of 7.5.TCS-OX2-29 displays ~250-fold selectivity for OX2 over OX1.	price>
R-R-3488	Vortioxetine-d8 hydrobromide	Vortioxetine-d8 (hydrobromide) is the deuterium labeled Vortioxetine hydrobromide. Vortioxetine hydrobromide is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with Ki values of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively.	price>
R-C-1789	Scriptaid (GCK 1026) CAS：287383-59-9	Scriptaid is a potent histone deacetylase(HDAC)inhibitor,used in cancer research.Scriptaid is also a sensitizer to antivirals and has potential for epstein-barr virus(EBV)-associated lymphomas treatment.	price>
R-R-3489	LE 300 CAS No.274694-98-3	LE 300/CAS No.274694-98-3 is a potent and selective dopamine D1-like receptor antagonist with Kis of 1.9 nM and 7.5 nM in CHO cell membranes expressing human dopamine D1 and D5 receptors, respectively. LE 300 is an antagonist of the 5-HT2A receptor with a pA2 of 8.32 in a rat tail artery assay.	price>
R-C-1790	S0859 CAS：1019331-10-2	S0859,an N-cyanosulphonamide compound,reversibly inhibit NBC-mediated pH(i) recovery(K(i)=1.7 microM,full inhibition at approximately 30 microM).	price>
R-R-3490	Rizatriptan-d6 benzoate CAS No.1216984-85-8	Rizatriptan-d6 (benzoate)/CAS No.1216984-85-8 is the deuterium labeled Rizatriptan benzoate. Rizatriptan benzoate is a 5-HT1 agonist triptan agent for the treatment of migraine headaches.	price>
R-C-1791	Cyantraniliprole (HGW-86) cas:736994-63-1	Cyantraniliprole(HGW-86)is an insecticide of the ryanoid class;has activity against pests such as Diaphorina citri that have developed resistance to other classes insecticides.	price>
R-R-3491	5-HT3 antagonist 5 CAS No.901599-43-7	5-HT3 antagonist 5/CAS No.901599-43-7 is a quinoxalin-2-carboxamide compound, a 5-HT3 receptor antagonist. 5-HT3 antagonist 5 exerts antagonism on 5-HT3 agonist and 2-methyl-5-HT, and shows anti-depressant effect in mice.	price>
R-C-1792	CZ415 CAS:1429639-50-8	CZ415 is a potent and highly selective mTOR inhibitor with a pIC50 of 8.07. CZ415 inhibits mTORC1 and mTORC2 protein complex.	price>
R-AC-0031	Calcium hydroxide loaded graphene aerogels	Calcium hydroxide loaded graphene aerogels/Ca(OH)2 loaded graphene aerogels/Calcium hydroxide loaded GO/Ca(OH)2 loaded GO from ruixi. The preparation method and application of graphene airgel composite materials loaded with calcium hydroxide belong to the technical field of graphene airgel and can solve the problems of limited absorption capacity and complicated production process of existing industrial harmful gas treatment and absorption methods. The invention adopts a step-by-step synthesis method. First, the precipitation method is used to synthesize calcium hydroxide particles, and the electrolytic oxidation method is used to synthesize graphene oxide. In the next step, the hydrothermal synthesis method is used to polymerize calcium hydroxide and graphene oxide, and finally the supported hydroxide is obtained. Calcium graphene airgel composite material. This composite material can be used in the field of chemical adsorption removal of acidic industrial harmful gases such as SO, HS, Cl, etc., and can also be used in the field of adsorption of VOCs gases such as benzene.	price>
R-C-1793	ID-8 CAS:147591-46-6	ID-8 is an inhibitor of dual-specificity tyrosine phosphorylation-regulated kinase(DYRK).ID-8 sustains embryonic stem cell(ESC)self-renewal and pluripotency.ID-8 enhances Wnt-mediated hESC survival and proliferation via inhibition of DYRKs.	price>
R-AC-0032	Aerogels doped with Fe based amorphous alloys	Aerogels doped with Fe based amorphous alloys/Aerogels doped with iron-based amorphous alloy from ruixi.Aerogels doped with iron-based amorphous alloys represent a novel and promising class of materials with diverse applications. These aerogels, known for their incredibly low density and high porosity, are further enhanced by the incorporation of Fe-based amorphous alloys, which impart unique properties to the material.The doping of aerogels with Fe-based amorphous alloys introduces several advantages. Firstly, amorphous alloys, characterized by their disordered atomic structure, offer exceptional mechanical properties, including high strength, hardness, and elasticity. When integrated into aerogels, these attributes improve the overall structural integrity and resilience of the material.Furthermore, the magnetic properties of Fe-based amorphous alloys can be leveraged within the aerogel matrix, enabling applications in fields such as magnetics, electronics, and sensors. This magnetic functionality can be tailored to specific requirements, opening up opportunities for use in diverse technological and industrial applications.	price>
R-C-1794	PLX8394 CAS:1393466-87-9	PLX8394 is a next-generation,orally available,small-molecule BRAF inhibitor with IC50 values of 3.8 nM,14 nM and 23 nM for BRAF(V600E),WT BRAF and CRAF respectively.It has potential antineoplastic activity.	price>
R-AC-0033	Polylactic acid-based bone repair composite aerogel	Polylactic acid-based bone repair composite aerogel/PLA-based bone repair composite aerogel from ruixi.Polylactic acid-based bone repair composite aerogel material is a cutting-edge biomedical material with excellent biocompatibility and bone repair capabilities. This material is based on polylactic acid. Through precise chemical synthesis and physical composite technology, the airgel material is closely combined with it to form a composite material with mechanical properties and biological activity. Its plasticity and processability enable personalized treatment and have broad application prospects, and are expected to bring breakthroughs in the treatment of orthopedic diseases.	price>
R-C-1795	Morantel Citrate CAS:69525-81-1	Morantel citrate is a potent non-binding site acetylcholine(ACh)receptor agonist that inhibits fumarate reductase.	price>
R-AC-0034	Ni(OH)2/N-rGO	Ni(OH)2/N-rGO;Ni(OH)2/N-reduced graphene oxide from ruixi.One-step hydrothermal method was used to fabricate a series of nickel hydroxide and nitrogen reduced graphene oxide composites (NGs) under different reaction time.The structure and physicochemical properties of the materials were characterized by XRD, FT-IR, Raman, XPS, SEM and N2-BET methods.The results show that the Ni (OH) 2 crystallites in the as-prepared material increased with the increase of reaction time, and the composites had mesoporous characteristics.The results of cyclic volt-ampere, charge-discharge and life test under three-electrode system show that the maximum capacitance of the series materials was 1 280F/g (NG-2) when the reaction time was 2h.The capacitance increased first and then decreased with the increasing reaction time, indicating that the capacitance of the materials would be related to the pore characteristics of the composite, Ni (OH) 2 grain size and the doping N atoms.	price>

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