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Catalog	name	Description	price
R-C-1877	Ziritaxestat (GLPG1690) CAS:1628260-79-6	Ziritaxestat(GLPG1690)is a first-in-class autotaxin(ATX)inhibitor,with an IC50 of 131 nM and Ki of 15nnM.	price>
R-R-3577	Inupadenant hydrochloride CAS No.2411004-22-1	Inupadenant (EOS-850) hydrochloride/CAS No.2411004-22-1 is an orally active, highly selective A2A receptor antagonist. Inupadenant hydrochloride is not brain-penetrant. Inupadenant hydrochloride has potent anti-tumor activity.	price>
R-C-1878	AZD-7594 CAS:1196509-60-0	AZD-7594(AZ13189620)is an inhaled selective glucocorticoid receptor(GCCR)modulator.AZD-7594 is in phase II clinical trials by AstraZeneca for the treatment of mild to moderate asthma.It is also in phase I clinical trials for the treatment of chronic obstructive pulmonary disorder(COPD).	price>
R-R-3578	Sipagladenant CAS No.858979-50-7	Sipagladenant (Compound I)/CAS No.858979-50-7 is an orally active adenosine receptor A2A inverse agonist. Sipagladenant can be used in frontal lobe dysfunction research.	price>
R-C-1879	KPT9274 CAS:1643913-93-2	KPT 9274(ATG-019)is an orally bioavailable small molecule that is a non-competitive dual inhibitor of PAK4 and NAMPT.It shows an IC50 of~120nM for NAMPT in a cell-free enzymatic assay.	price>
R-R-3579	SDZ-WAG994 CAS No.130714-47-5	SDZ-WAG994 (WAG-994)/CAS No.130714-47-5 is a stable, long-acting, selective and orally active A1-adenosine receptor agonist with a KD of 23 nM. SDZ-WAG994 can be used for the research of atrial fibrillation.	price>
R-C-1880	LX-2343 CAS:333745-53-2	LX2343 is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 μM.LX2343 acts as a non-ATP competitive PI3K inhibitor with an IC50 of 15.99±3.23μM.LX2343 stimulates autophagy in its promotion of Aβ clearance.	price>
R-R-3580	Alloxazine CAS No.490-59-5	Alloxazine/CAS No.490-59-5 is a selective A2b antagonist. Alloxazine completely block 5 N-Ethylcarboxamido adenosine (NECA)-mediated cyclic AMP accumulation with an IC50 of 2.9 μM. Alloxazine can be used for the research of cancer.	price>
R-C-1881	ML355 CAS:1532593-30-8	ML355 is a potent and selective inhibitor of 12-Lipoxygenase(12-LOX)with an IC50 of 0.34μM,shows excellent selectivity over related lipoxygenases and cyclooxygenases,and possesses favorable ADME properties.	price>
R-R-3581	ST 1535 CAS No.496955-42-1	ST 1535/CAS No.496955-42-1 is a potent and orally active A2A adenosine receptor antagonist. ST 1535 shows antiparkinsonian activity and antitremorigenic effects. ST 1535 has the potential for the research of Parkinson disease.	price>
R-C-1882	Evobrutinib (M-2951) CAS:1415823-73-2	Evobrutinib(M-2951,MSC-2364447C)is a highly selective BTK inhibitor with an IC50 of 37.9 nM.It has potential anti-neoplastic activity.	price>
R-R-3582	Binodenoson CAS No.144348-08-3	Binodenoson (MRE-0470)/CAS No.144348-08-3 is a potent and selective A2A adenosine receptor agonist (KD=270 nM). Binodenoson is being developed as a short-acting coronary vasodilator as an adjunct to radiotracers for use in myocardial stress imaging.	price>
R-C-1883	SSR240612 CAS:464930-42-5	SSR240612 is a potent,and orally active specific non-peptide bradykinin B1 receptor antagonist,with Kis of 0.48 nM and 0.73nM for B1 kinin receptors of human fibroblast MRC5 and HEK cells expressing human B1 receptors,481nM and 358 nM for B2 receptors of guinea pig ileum membranes and CHO cells expressing human B1 receptor,respectively.	price>
R-R-3583	CL 316243 CAS No.138908-40-4	CL316243/CAS No.138908-40-4 is a highly potent selective β3-adrenoceptor agonist with a EC50 of 3 nM, but is an extremely poor to β1/2- receptors.CL316243 is a effective stimulant of adipocyte lipolysis and increases brown adipose tissue thermogenesis and metabolic rate. CL316243 has the potential for the treatment obesity, diabetes and urge urinary incontinence.	price>
R-C-1884	FH1(BRD-K4477) CAS： 2719-05-3	FH1(NSC 12407)enhances hepatocyte functions,and promotes the differentiation of induced pluripotent stem(iPS)-derived hepatocytes toward a phenotype more mature and the maturation of well-differentiated cultures of hepatocyte-like cells (iHeps).	price>
R-R-3584	Propranolol CAS No.525-66-6	Propranolol/CAS No.525-66-6 is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively. Propranolol inhibits [3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM. Propranolol is used for the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy.	price>
R-C-1885	Saquinavir mesylate CAS：149845-06-7	Saquinavir mesylate is an HIV Protease Inhibitor used in antiretroviral therapy.	price>
R-R-3585	Zenidolol hydrochloride CAS No.72795-01-8	Zenidolol (ICI-118551) hydrochloride/CAS No.72795-01-8 is a highly selective β2 adrenergic receptor antagonist, with Kis of 0.7, 49.5 and 611 nM for β2, β1 and β3 receptors, respectively.	price>
R-C-1886	Crenigacestat (LY3039478) CAS：1421438-81-4	LY3039478 is a orally bioavailable,novel small molecule Notch inhibitor with an IC50 of ~1nM in most of the tumor cell lines tested.	price>
R-R-3586	BRL-44408 maleate CAS No.681806-46-2	BRL-44408 maleate/CAS No.681806-46-2 is an α2A-adrenoceptor antagonist (Ki: 8.5 nM). BRL-44408 maleate has antidepressant and analgesic activity. BRL-44408 also improves cecal ligation puncture (CLP)-induced acute lung injury.	price>

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