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Catalog	name	Description	price
R-C-1910	Cerdulatinib CAS：1198300-79-6	Cerdulatinib(PRT-062070)is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12nM/6nM/8 nM/0.5nM and 32nM for JAK1/JAK2/JAK3/TYK2 and Syk.	price>
R-R-3610	Vilanterol CAS No.503068-34-6	Vilanterol (GW642444)/CAS No.503068-34-6 is a long-acting β2-adrenoceptor (β2-AR) agonist with 24 h activity. The pEC50s for β2-AR,β1-AR and β3-AR is 10.37±0.05, 6.98±0.03 and 7.36±0.03, respectively.	price>
R-C-1911	Tomivosertib (eFT-508) CAS：1849590-01-7	Tomivosertib(eFT-508)is a potent and selective MNK1/2 inhibitor with IC50s of 2.4nM and 1 nM,respectively.It potentially results in decreased tumor cell proliferation and tumor growth.Tomivosertib(eFT-508)inhibits eIF4E phosphorylation and dramatically downregulates PD-L1 protein abundance.	price>
R-R-3611	(R)-Propranolol hydrochloride CAS No.13071-11-9	(R)-Propranolol hydrochloride/CAS No.13071-11-9 is a less active enantiomer of the β-adrenoceptor antagonist propranolol (HY-B0573). Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively.	price>
R-C-1912	SM164 CAS：957135-43-2	SM-164 is a potent,non-peptide,cell-permeable antagonist of XIAP that targets both the BIR2 and BIR3 domains with IC50 of 1.39nM.SM-164 induces apoptosis and tumor regression.	price>
R-R-3612	Rauwolscine hydrochloride CAS No.6211-32-1	Rauwolscine hydrochloride/CAS No.6211-32-1 is a potent and specific α2 adrenergic receptor antagonist with a Ki of 12 nM.	price>
R-C-1913	LY3200882 CAS： 1898283-02-7	LY 3200882 is a potent,highly selective inhibitor of TGF-β receptor type 1(TGFβRI).It potently inhibits TGFβ mediated SMAD phosphorylation in vitro in tumor and immune cells and in vivo in subcutaneous tumors in a dose dependent fashion.	price>
R-R-3613	Acebutolol hydrochloride CAS No.34381-68-5	Acebutolol hydrochloride/CAS No.34381-68-5 is an orally active β1 adrenergic receptor (β1AR) antagonist. Acebutolol hydrochloride is used in the treatment of hypertension, angina pectoris and cardiac arrhythmias.	price>
R-C-1914	LY2795050 CAS：1346133-08-1	LY2795050 is a novel selective κ-opioid Receptor(KOR)antagonist(IC50=0.72nM) and has the potential as a PET tracer to image KOR in vivo.	price>
R-R-3614	Midodrine hydrochloride CAS No.43218-56-0	Midodrine hydrochloride ((±)-Midodrine hydrochloride)/CAS No.43218-56-0 is an α1-receptor agonist, for the treatment of dysautonomia and orthostatic hypotension.	price>
R-C-1915	DWK-1339 CAS：1018946-38-7	MDR-1339(DWK-1339)is an orally active and blood-brain-barrier-permeable Aβ-aggregation inhibitor,used in the research of Alzheimer is disease.	price>
R-R-3615	Penbutolol sulfate CAS No.38363-32-5	Penbutolol sulfate/CAS No.38363-32-5 is able to bind to both beta-1 adrenergic receptors and beta-2 adrenergic receptors (the two subtypes), thus making it a non-selective β blocker.	price>
R-C-1916	Itanapraced (CHF 5074) CAS:749269-83-8	Itanapraced(CHF 5074,CSP-1103)is a gamma-secretase modulator that reduces Aβ42 and Aβ40 secretion.The IC50s of CHF5074 for inhibition of COX-1 and COX-2 is above 100μmol/L.	price>
R-R-3616	JP1302 dihydrochloride CAS No.1259314-65-2	JP1302 dihydrochloride/CAS No.1259314-65-2 is a potent, selective, high affinity antagonist of the α2C-adrenoceptor, with a Kb of 16 nM and a Ki of 28 nM for the human α2C-receptor. JP1302 dihydrochloride shows antidepressant and antipsychotic-like effects. JP1302 dihydrochloride can be used for neuropsychiatric disorders and renal dysfunction research.	price>
R-C-1917	Pralsetinib (BLU-667) CAS:2097132-94-8	Pralsetinib(BLU-667,CS 3009,Gavreto)is a highly potent and selective RET (c-RET)inhibitor with an IC50 of 0.4 nM for WT RET.It also demonstrates potent activity(IC50 0.4 nmol/L)against common oncogenic RET alterations,including RET(M918T).	price>
R-R-3617	Medetomidine hydrochloride CAS No.86347-15-1	Medetomidine hydrochloride/CAS No.86347-15-1 is an orally active α2-adrenoceptor agonist (Ki: 1.08 nM). Medetomidine hydrochloride has sedative and analgesic effects. Medetomidine hydrochloride can cause peripheral vasoconstriction through the activation of α2 adrenoceptors on blood vessels.	price>
R-C-1918	SKL 2001 CAS:909089-13-0	SKL2001 is an agonist of the Wnt/β-catenin pathway,with anti-cancer activity. SKL2001 stabilizes intracellular β-catenin via disruption of the Axin/β-catenin interaction.	price>
R-R-3618	2-Methoxyidazoxan monohydrochloride CAS No.109544-45-8	2-Methoxyidazoxan monohydrochloride (RX821002 hydrochloride)/CAS No.109544-45-8 is a highly selective alpha 2-adrenoceptor antagonist with little or no imidazoline antagonist effect. RX 821002 has markedly higher affinity for (guinea-pig) alpha 2D-adrenoceptors (pKd 9.7) than for (rabbit) alpha 2A-adrenoceptors (pKd 8.2).	price>
R-C-1919	PJ34 CAS: 344458-19-1	PJ34 is a potent specific inhibitor of PARPl/2 with IC50 of 110nM and 86nM, respectively.	price>
R-R-3619	(R)-Carvedilol CAS No.95093-99-5	(R)-Carvedilol ((R)-BM 14190)/CAS No.95093-99-5, the R-enantiomer of Carvedilol, is a non-selective β/α-1 blocker. (R)-Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX).	price>

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