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R-C-1930 AM095 CAS: 1228690-36-5 AM095 is a potent LPA1 receptor antagonist because it inhibited GTPγS binding to Chinese hamster ovary(CHO)cell membranes overexpressing recombinant human or mouse LPA1 with IC50 values of 0.98 and 0.73μM,respectively,and exhibited no LPA1 agonism.Lysophosphatidic acid(LPA)is a bioactive phospholipid that signals through a family of at least six G protein-coupled receptors designated LPA1-6. LPA type 1 receptor(LPA1)exhibits widespread tissue distribution and regulates a variety of physiological and pathological cellular functions. price>
R-R-3630 PCL hyaluronic acid nanofiber membrane PCL hyaluronic acid nanofiber membrane/Polycaprolactone hyaluronic acid nanofiber membrane from ruixi.PCL hyaluronic acid nanofiber membranes are composite materials produced through the electrospinning process, integrating Polycaprolactone (PCL) and hyaluronic acid. The tailored properties of PCL hyaluronic acid nanofiber membranes make them suitable for a wide range of potential biomedical applications, such as wound dressings, drug delivery systems, and scaffolds for tissue engineering. The ability to modify the physical characteristics of the membrane, including pore size, porosity, and degradation kinetics, through adjusting the electrospinning parameters makes it highly versatile for specific tissue engineering requirements. price>
R-C-1931 EHT5372 CAS :1425945-63-6 EHT 5372 is a highly potent and selective inhibitor of DYRK isfamily kinases with IC50s of 0.22,0.28,10.8,93.2,22.8,88.8,59.0,7.44,221 nM for DYRK1A,DYRK1B,DYRK2,DYRK3,CLK1,CLK2,CLK4,GSK-3α,GSK-3β. price>
R-R-3631 PCL silk fibroin nanofiber membrane PCL silk fibroin nanofiber membrane/Polycaprolactone silk fibroin nanofiber membrane from ruixi.PCL silk fibroin nanofiber membrane is a nanofiber membrane material that combines polycaprolactone (PCL) and silk fibroin. As a biodegradable polyester, PCL has good mechanical properties and biocompatibility, while silk fibroin is a natural polymer protein with good biological activity and mechanical properties. Combining PCL and silk fibroin to form a nanofiber membrane can combine the advantages of both and improve the biocompatibility, mechanical properties and functionality of the material. Pcl silk fibroin nanofiber membranes are also usually prepared by electrospinning. By controlling the spinning parameters, fibers with nanometer diameters can be obtained. This fiber membrane material has high specific surface area, high porosity and good biological activity, so it can be used in tissue engineering, wound dressings, drug delivery and biosensors. In addition, due to the good biocompatibility and biological activity of silk fibroin, the Pcl silk fibroin nanofiber membrane can also promote cell adhesion and proliferation, thereby promoting tissue regeneration and repair. Therefore, this material has broad application prospects in the biomedical field. price>
R-C-1932 Verubecestat (MK-8931) Verubecestat(MK-8931)is an orally active,high-affinity BACE1 and BACE2 inhibitor with Ki values of 2.2nM and 0.38nM. Verubecestat effectively reduces Aβ40 and has the potential for Alzheimer is Disease. price>
R-R-3632 PCL silk fibroin electrospun membrane PCL silk fibroin electrospun membrane/Polycaprolactone silk fibroin electrospun membrane from ruixi. PCL silk fibroin electrospun membranes are composite materials created through the electrospinning process, combining Polycaprolactone (PCL) and silk fibroin. PCL silk fibroin electrospun membranes represent an exciting and promising material for tissue engineering, regenerative medicine, and related biomedical fields, given their ability to provide a biomimetic microenvironment that supports cell growth and tissue regeneration. This particular combination of materials opens up new avenues for advancing biomedical research and clinical applications. price>
R-C-1933 ALVELESTAT (AZD 9668) CAS:848141-11-7 Alvelestat(AZD9668,Avelestat)is an oral,highly selective inhibitor of neutrophil elastase(NE)with IC50 and Ki of 12nM and 9.4nM,at least 600-fold more selective over other serine proteases.  price>
R-R-3633 PLA/gelatin electrospun nanofiber membrane Polylactic acid/gelatin electrospun nanofiber membrane is a nanofiber membrane material that combines polylactic acid (PLA) and gelatin. Polylactic acid is a biodegradable polymer material with good mechanical properties and biocompatibility; gelatin is a natural polymer material derived from animal bones and skin and other tissues, and has good biological activity and adhesion. Through electrospinning technology, polylactic acid and gelatin can be combined to form a nanoscale fiber membrane. This membrane material combines the advantages of both and shows better performance and application prospects.Polylactic acid (gelatin) electrospun nanofiber membrane has high specific surface area, high porosity and good biological activity, so it can provide a good environment for cell growth and material transmission, promote cell adhesion and proliferation, in addition, due to the adhesiveness of gelatin This kind of fiber membrane also has good adhesion properties and can closely adhere to the tissue surface, helping to repair and regenerate the tissue. In the field of tissue engineering, polylactic acid/gelatin electrospinning nanofiber membrane can be used as a scaffold material, supports the growth and differentiation of cells, and promotes tissue regeneration and repair. At the same time, due to the biodegradability of polylactic acid, this fiber membrane material can be gradually degraded and absorbed in the body, avoiding the need for secondary surgical removal. In addition , polylactic acid/gelatin electrospun nanofiber membranes can also be used in fields such as drug delivery, wound dressings and biosensors. By loading bioactive substances such as drugs or growth factors, sustained release and targeted delivery of drugs can be achieved, improving drug delivery. therapeutic effect and reduce side effects. price>
R-C-1934 BAY 80-6946 CAS:1032568-63-0 Copanlisib(BAY80-6946)is a potent,selective and ATP-competitive pan-class I PI3K inhibitor,with IC50s of 0.5nM,0.7nM,3.7nM and 6.4nM for PI3Kα,PI3Kδ,PI3Kβ and PI3Kγ,respectively.Copanlisib has more than 2,000-fold selectivity against other lipid and protein kinases,except for mTOR. Copanlisib has superior antitumor activity. price>
R-R-3634 PLGA composite silk fibroin electrospun fiber membrane PLGA composite silk fibroin electrospun fiber membrane/Poly(lactic-co-glycolic acid) composite silk fibroin electrospun fiber membrane from ruixi. PLGA composite silk fibroin electrospun fiber membrane is an electrospun fiber membrane material that combines Poly(lactic-co-glycolic acid) (PLGA) and silk fibroin. PLGA is a biodegradable polyester with good mechanical properties and biocompatibility, while silk fibroin is a natural polymer protein with good biological activity and mechanical properties. Through electrospinning technology, PLGA and silk fibroin can be combined to form nanoscale fiber membranes with high specific surface area and porosity, providing a good environment for cell growth and material transmission. PLGA composite silk fibroin electrospun fiber membrane has broad application prospects in the biomedical field, such as tissue engineering, drug delivery, wound dressings, etc. Its good biocompatibility and mechanical properties can promote cell adhesion and proliferation, thereby promoting tissue regeneration and repair. At the same time, the biodegradability of PLGA allows this fiber membrane material to be gradually degraded and absorbed in the body, avoiding the need for secondary surgical removal. In addition, the PLGA composite silk fibroin electrospun fiber membrane can also be adjusted by adjusting spinning parameters and adding Growth factors and other methods are modified to improve its performance and functionality. For example, bioactive substances such as growth factors can be added to promote cell differentiation and functional expression. price>
R-C-1935 RRx-001 CAS:925206-65-1 RRx-001 is a novel epigenetic modulator with potential radiosensitizing activity.It inhibits glucose 6-phosphate dehydrogenase(G6PD)in human tumor cells,binds hemoglobin and drives RBC-mediated redox reactions under hypoxia. RRx-001 triggers apoptosis and exhibits anticancer activity. price>
R-R-3635 Glutaraldehyde cross-linked PVA membrane Glutaraldehyde cross-linked polyvinyl alcohol membrane/Glutaraldehyde cross-linked PVA membrane from ruixi.Glutaraldehyde cross-linked polyvinyl alcohol (PVA) membranes are a type of specialized material that has found extensive use in biomedical and separation applications. Glutaraldehyde cross-linked polyvinyl alcohol (PVA) membranes represent an innovative advancement in membrane technology, particularly in biomedical and separation applications. The controlled cross-linking process introduces valuable properties that enable the membranes to be used effectively in tissue engineering, controlled drug delivery, and precise separation processes. These membranes continue to play a significant role in various fields due to their tailored characteristics and specific applications. price>
R-C-1936 GIGANTOL CAS:67884-30-4 Gigantol is a bibenzyl compound derived from several medicinal orchids.Giganto shows promising therapeutic potential against cancer cells.Gigantol is a novel inhibitor of the Wnt/β-catenin pathway. price>
R-R-3636 PLGA silk fibroin nanofiber membrane PLGA silk fibroin nanofiber membrane/Poly(lactic-co-glycolic acid) silk fibroin nanofiber membrane from ruixi. PLGA (Poly(lactic-co-glycolic acid)) silk fibroin nanofiber membranes are a combination of biocompatible and biodegradable polymers that have been engineered at the nanoscale level. PLGA silk fibroin nanofiber membranes offer a unique combination of properties, including biocompatibility, biodegradability, high surface area, and mechanical flexibility, making them valuable in various biomedical applications. These membranes continue to be a subject of intense interest for researchers and engineers working in tissue engineering, drug delivery, wound healing, and regenerative medicine due to their tailored properties and versatile applications. price>
R-C-1937 S119-8 CAS:443639-96-1 S119-8 is a broad spectrum inhibitor of influenza A and B viruses,showing activity against multiple influenza B viruses and an oseltamivir-resistant influenza A virus,but does not inhibit a non-influenza virus,vesicular stomatitis nirus(VSV). price>
R-R-3637 PAN electrospun fiber membrane PAN electrospun fiber membrane/Polyacrylonitrile electrospun fiber membrane from ruixi. The PAN nanofiber membrane prepared by electrospinning has better piezoelectric properties than PVDF nanofiber membrane. The static charge in PAN nanofibers facilitates the conversion of piezoelectric energy. The electrical energy generated by PAN nanofiber films can provide power for commercial LEDs. Nanomaterials prepared by electrospinning can be applied in various fields such as biopolymer materials, battery separators, filtration materials, catalysts, sensors, etc price>
R-C-1938 NAV-2729 CAS: 419547-11-8 NAV-2729 is a selective ARF6 inhibitor(IC50=1.0μM).Blocking ARF6 with a small-molecule inhibitor reduces uveal melanoma cell proliferation and tumorigenesis in a mouse model,confirming the functional relevance of this pathway and suggesting a therapeutic strategy for Gα-mediated diseases. price>
R-R-3638 PCL-SF electrospun fiber membrane PCL-SF electrospun fiber membrane/Polycaprolactone-SilkFibroin electrospun fiber membrane from ruixi.Electrospun fiber membranes made from a blend of polycaprolactone (PCL) and silk fibroin (SF) are advanced materials that find diverse applications in biomedical engineering, tissue regeneration, and drug delivery systems. Electrospun fiber membranes made from a blend of PCL and SF offer a unique combination of biocompatibility, mechanical strength, and controlled drug delivery capabilities. These membranes are valuable in a range of biomedical applications, including tissue engineering, wound healing, and controlled drug release systems, owing to their tailored characteristics and versatile potential in various therapeutic and regenerative medicine applications. price>
R-C-1939 INF-39 CAS:866028-26-4 INF39 is a nontoxic,irreversible NLRP3 inhibitor that counteracts NLRP3 activation through direct irreversible interaction with NLRP3 and partial inhibition of LPS-driven pro-inflammatory gene expression. price>
R-R-3639 Ppy ps membrane Ppy ps membrane/Polypyrrole polystyrene membrane from ruixi.A polypyrrole (Ppy) polystyrene (PS) membrane is a composite material that combines the unique properties of polypyrrole and polystyrene, offering a range of applications in fields such as electrochemistry, sensors, and filtration.Ppy-PS membranes represent a versatile composite material with a unique combination of electrical conductivity, selective permeability, and chemical stability. Their potential applications span various fields, including electrochemistry, sensors, filtration, energy storage, and biomedical engineering, making them an area of interest for researchers and engineers seeking advanced materials with tailored properties for specific applications. price>