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R-R-3767 5,10,15,20-Tetrakis(4-carboxymethyloxyphenyl)porphyrin CAS :127812-08-2 Tetrakis(4-carboxymethyloxyphenyl)porphyrin (TCMP)/CAS :127812-08-2 is a singlet oxygen emitting compound. Singlet oxygen can react with lipid and protein molecules, generating reactive oxygen species such as hydroperoxides and hydrogen peroxide. TCMP has been found to enhance the production of reactive oxygen species in mitochondria, which may be due to its ability to transfer energy from the electron transport chain to the respiratory chain. TCMP also has a peroxidative effect on rat brain tissue, leading to an increase in marker enzyme activity and lipid hydroperoxides. We can mass produce (kg level), process scaling up, pilot supply, raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time. price>
R-C-2068 MC-VAL-CIT-PAB    CAS:159857-80-4 MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate.FDA approved drugs such as brentuximab vedotin use this linker. price>
R-R-3768 5,10,15,20-Tetrakis(4-hydroxyphenyl)porphyrin CAS :51094-17-8 5,10,15,20-Tetrakis(4-hydroxyphenyl)-21H,23H-porphine(CAS:51094-17-8) has a wide range of scientific research applications due to its unique structure and properties. It has been used in studies of enzyme-catalyzed reactions, protein-ligand interactions, and DNA-protein interactions. It has also been used in studies of the photochemistry and photobiology of porphyrins. We can mass produce (kg level), process scaling up, pilot supply, raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time. price>
R-C-2069 JAK3-IN-6  CAS:1443235-95-7 JAK3-IN-6 is a potent,selective irreversible Janus Associated Kinase 3(JAK3) inhibitor,with an IC50 of 0.15nM. price>
R-R-3769 5,10,15,20-Tetrakis(pentafluorophenyl)porphyrin CAS :25440-14-6 5,10,15,20-Tetrakis(pentafluorophenyl)porphyrin/CAS :25440-14-6 is a highly sensitive optical sensor that can be used to detect the presence of benzyl groups in wastewater. It has been shown to be an effective antimicrobial treatment for wastewater containing organic matter at subcritical and supercritical conditions. The kinetics of 5,10,15,20-tetrakis(pentafluorophenyl)porphyrin are dependent on the kinetic parameters of the reaction such as light emission and the activation energies. We can mass produce (kg level), process scaling up, pilot supply, raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time. price>
R-R-3770 Cobalt tetramethoxyphenylporphyrin CAS :28903-71-1 Cobalt tetramethoxyphenylporphyrin/5,10,15,20-Tetrakis (4-methoxyphenyl)-21H,23H-porphine cobalt (II)/CAS :28903-71-1 is a metal chelate that binds to hydroxyl groups of organic compounds and removes them from wastewater. Cobalt tetramethoxyphenylporphyrin has been shown to be a stable complex, with the proton being bound to the metal atom. The basic structure of this metal chelate is methoxy groups, which are electron-donating groups. The oxidation catalyst for this reaction mechanism is activated by heat and light. This reaction mechanism can proceed in neutral or alkaline conditions. Activation energies for this type of chemical reaction are often high due to the need for the electrons to be transferred from one molecule to another. We can mass produce (kg level), process scaling up, pilot supply, raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time. price>
R-C-2071 Branebrutinib (BMS-986195) CAS:1912445-55-6 Branebrutinib(BMS-986195)is a highly potent,selective covalent,irreversible inhibitor of Bruton is tyrosine kinase(BTK),with an IC50 of 0.1nM. price>
R-R-3771 5,10,15,20-Tetra(4-pyridyl)porphyrin CAS:16834-13-2 Tetra(4-pyridyl)porphyrin (TPP)/CAS:16834-13-2 is a model system for studying the interaction of silver ions and inhibitor molecules. TPP is a coordination compound with the chemical formula C20H14N2O3P4. It has been shown to be an efficient inhibitor of tumor xenografts, inhibiting cell cytoplasmic processes such as protein synthesis and DNA replication. The reaction mechanism of this compound has been studied by multi-walled carbon, electrochemical impedance spectroscopy, Langmuir adsorption isotherms, and fluorescence properties. The binding constants for TPP have been determined to be in the range of 109 - 1010 L mol-1. We can mass produce (kg level), process scaling up, pilot supply, raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time. price>
R-C-2072 Astemizole CAS: 68844-77-9 Astemizole is a potent antihistamine(H1-receptor antagonist,IC50=4nM)that displays selectivity over dopamine,5-HT,and muscarinic acetylcholine receptors.This compound has shown potent hERG K+ channel blocking activity (IC50=0.9nM),antimalarial activity in multidrug resistant strains in vitro(IC50=227-734nM),and has been used as a chaperone to correct folding defects and restore protein function for some mutated forms of hERG channels. price>
R-R-3772 Titanyl Phthalocyanine CAS :26201-32-1 Titanyl Phthalocyanine (PtPc)/CAS :26201-32-1 is a metal-organic compound that belongs to the class of phthalocyanines. It has been purified through sublimation. Pt Pc can be used as a ligand for metals such as titanium, which is an important material in many industrial applications. This compound has been shown to fluoresce under ultraviolet light and can be used to study the properties of monolayers and bilayers. The Langmuir adsorption technique is used to measure the energies of PtPc at the interface between two phases, which are monolayers or bilayers. We can mass produce (kg level), process scaling up, pilot supply, raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time. price>
R-C-2073 Oxaliplatin CAS:61825-94-3 Oxaliplatin is an organoplatinum complex in which the platinum atom is complexed with 1,2-diaminocyclohexane(DACH)and with an oxalate ligand as a leaving group.A leaving group is an atom or a group of atoms that is displaced as a stable species taking with it the bonding electrons.The DACH side chain appears to inhibit alkylating-agent resistance. price>
R-R-3773 Zinc(II) Tetraphenylporphyrin CAS :14074-80-7 Zinc(II) Tetraphenylporphyrin/CAS :14074-80-7 is a natural organic compound that can be found in the human body. It has been shown to have anti-angiogenic properties and can be used for the treatment of choroidal neovascularization (CNV). Tetraphenylporphyrin is a redox active molecule that has a high redox potential, which makes it an ideal candidate for use in photoactive systems. Tetraphenylporphyrin has been shown to inhibit the proliferation of tumor cells by interfering with lipid synthesis and transferring electrons from one molecule to another. The chemical structure of tetraphenylporphyrin makes it possible for light exposure to induce a frequency shift, which leads to light emission at 590 nm. This emission is due to the hydroxyl group present on tetraphenylporphyrin, which acts as an electron donor. We can mass produce (kg level), process scaling up, pilot supply, raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time. price>
R-C-2074 CCT245737 CAS:1489389-18-5 CCT245737 is a potent, selective and orally active checkpoint kinase 1(CHK1) inhibitor.CCT245737 showed CHK1 IC50=1.3nM,CHK2 IC50=2440nM,G2 check point abrogation IC50=30nM.Mouse F(oral)=100%.CCT245737 demonstrated a favorable physicochemical,PK,and PD-efficacy profile.The serine-threonine kinase CHK1 is a critical component of the cellular response to DNA damage,especially the repair of DNA breaks arising during replication or caused by DNA damaging chemotherapies and ionizing radiation. price>
R-R-3774 Terazosin hydrochloride CAS No.63074-08-8 Terazosin hydrochloride/CAS No.63074-08-8 is a quinazoline derivative and a competitive and orally active α1-adrenoceptor antagonist. Terazosin hydrochloride works by relaxing blood vessels and the opening of the bladder. Terazosin hydrochloride has the potential for benign prostatic hyperplasia (BPH) and high blood pressure treatment. price>
R-C-2075 SJB2-043 CAS:63388-44-3 SJB2-043 is one of analogs/derivatives of C527,which is a novel and potent USP1 (ubiquitin-specific protease 1)inhibitor. price>
R-R-3775 Levobunolol hydrochloride CAS No.27912-14-7 Levobunolol (l-Bunolol) hydrochloride/CAS No.27912-14-7 is a potent and nonselective β-adrenergic receptor antagonist. Levobunolol hydrochloride is an ocular hypotensive agent and lowers mean intraocular pressure (IOP). Levobunolol hydrochloride can be used for glaucoma and superior oblique myokymia (SOM) research. price>
R-C-2076 SU14813 CAS: 627908-92-3 SU14813 is a multi-targeted receptor tyrosine kinases inhibitor with IC50s of 50,2,4,15 nM for VEGFR2,VEGFR1,PDGFRβ and KIT. price>
R-R-3776 Isoferulic acid CAS No.537-73-5 Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid)/CAS No.537-73-5 is a cinnamic acid derivative that has antidiabetic activity. Isoferulic acid binds to and activates α1-adrenergic receptors (IC50=1.4 µM) to enhance secretion of β-endorphin (EC50=52.2 nM) and increase glucose use. Isoferulic acid also has anti-influenza virus activities. price>
R-R-3777 Medetomidine CAS No.86347-14-0 Medetomidine/CAS No.86347-14-0 is an orally active α2-adrenoceptor agonist (Ki: 1.08 nM). Medetomidine has sedative and analgesic effects. Medetomidine can cause peripheral vasoconstriction through the activation of α2 adrenoceptors on blood vessels. price>
R-C-2078 Fmoc-Ser(Ac3GalNAcα)-OH CAS:120173-57-1 Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH is a drug for cancer. price>