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Catalog	name	Description	price
R-R-3778	Bevantolol hydrochloride CAS No.42864-78-8	Bevantolol hydrochloride/CAS No.42864-78-8 is a selective β1 and α1-adrenergic receptor antagonist with pKi values of 7.83, 6.9 in rat cerebral cortex, respectively. Bevantolol hydrochloride is a potent Ca2+ antagonist.	price>
R-C-2079	E-7046 CAS：1369489-71-3	E7046 is an orally bioavailable and specific EP4 antagonist,with IC50 of 13.5nM and Ki of 23.14nM,exhibiting anti-tumor activities.	price>
R-R-3779	Bambuterol hydrochloride CAS No.81732-46-9	Bambuterol hydrochloride/CAS No.81732-46-9 ((±)-Bambuterol hydrochloride; KWD-2183 hydrochloride) is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; it also is a proagent of terbutaline.	price>
R-C-2080	Bemcentinib (R428) CAS：1037624-75-1	Bemcentinib(R428,BGB324)is an inhibitor of Axl with IC50 of 14 nM,>100-fold selective for Axl versus Abl.Selectivty for Axl is also greater than Mer and Tyro3(50-to-100- fold more selective)and InsR,EGFR,HER2,and PDGFRβ(100- fold more selective).	price>
R-R-3780	Dabuzalgron CAS No.219311-44-1	Dabuzalgron (Ro 115-1240)/CAS No.219311-44-1 is an orally active and selective α-1A adrenergic receptor agonist for the treatment of urinary incontinence. Dabuzalgron protects against Doxorubicin-induced cardiotoxicity by preserving mitochondrial function.	price>
R-C-2081	CPI-444 CAS：1202402-40-1	Ciforadenant(CPI-444,V81444)is a potent and selective Adenosine A2A receptor antagonist.It binds to A2A receptors with a Ki of 3.54 nmol/L and demonstrates a greater than 50-fold selectivity for the A2A receptor over other adenosine receptor subtypes.	price>
R-R-3781	Esmolol hydrochloride CAS No.81161-17-3	Esmolol hydrochloride/CAS No.81161-17-3 is a beta adrenergic receptor blocker.	price>
R-C-2082	ars-1620 CAS：1698055-85-4	ARS-1620 is a potent,orally bioavailable covalent inhibitor of KRAS-G12C and could achieve rapid and sustained in vivo target occupancy to induce tumor regression.	price>
R-R-3782	Glaucine CAS No.475-81-0	Glaucine (O,O-Dimethylisoboldine)/CAS No.475-81-0 is an alkaloid isolated from Glaucium flavum with antitussive, bronchodilation and anti-inflammatory properties. Glaucine is a selective and orally active phosphodiesterase 4 (PDE4) inhibitor with Kis of 3.4 µM in human bronchus and polymorphonuclear leukocytes. Glaucine is also a non-selective α-adrenoceptor antagonist, a Ca2+ entry blocker, and a weak dopamine D1 and D2 receptor antagonist. Glaucine has antioxidative and antiviral activities.	price>
R-C-2083	USP25 and 28 inhibitor AZ-1 CAS：2165322-94-9	USP25/28 inhibitor AZ1(AZ1)is an orally active,selective,noncompetitive, dual ubiquitin specific protease(USP)25/28 inhibitor with IC50s of 0.7μM and 0.6 μM,respectively.USP25/28 inhibitor AZ1 attenuates colitis and tumorigenesis in the mice model.	price>
R-R-3783	Detomidine hydrochloride CAS No.90038-01-0	Detomidine hydrochloride/CAS No.90038-01-0, an imidazole derivative, is a potent α2-adrenergic agonist. Detomidine hydrochloride produces dose-dependent analgesic effects.	price>
R-C-2084	Belvarafenib (HM95573) CAS:1446113-23-0	Belvarafenib(GDC5573,HM95573,RG6185)is a selective and orally bioavailable pan-RAF kinase inhibitor with IC50 values of 41 nM,7nM and 2nM for BRAF WT, BRAF(V600E)and CRAF kinases,respectively.	price>
R-R-3784	Hydrocortisone 17-butyrate CAS No.13609-67-1	Hydrocortisone 17-butyrate/CAS No.13609-67-1 is an adrenocortical hormone active molecule.	price>
R-C-2085	Q-VD-OPh hydrate CAS:1135695-98-5	Q-VD-OPh is an irreversible pan-caspase inhibitor with potent antiapoptotic properties,inhibits caspase 7 with an IC50 of 48nM and 25-400nM for other caspases including caspase 1,3,8,9,10,and 12.Q-VD-OPh can inhibits HIV infection.Q-VD-OPh is able to cross the blood-brain barrier.	price>
R-R-3785	Ro 363 hydrochloride CAS No.250580-70-2	Ro 363 hydrochloride/CAS No.250580-70-2, an effective inotropic stimulant, is a potent and highly selective β1-adrenoceptor agonist. Ro 363 hydrochloride is a cardiovascular modulator that reduces diastolic blood pressure and pronounces increases in myocardial contractility.	price>
R-C-2086	GSK2983559 FREE ACID CAS:1579965-12-0	GSK2983559 free acid(compound 3)is a potent,specific and oral active receptor interacting protein 2(RIP2)kinase inhibitor.GSK2983559 free acid has excellent activity in blocking many proinflammatory cytokine responses in vivo and in human inflammatory bowel disease explant samples.	price>
R-R-3786	Lofexidine CAS No.31036-80-3	Lofexidine/CAS No.31036-80-3 is a selective α2-receptor agonist, commonly used to alleviate the physical symptoms of heroin and other types of opioid withdrawal.	price>
R-C-2087	Elexacaftor (VX-445) CAS:2216712-66-0	Elexacaftor(VX-445,Compound 1)is a modulator of cystic fibrosis transmembrane conductance regulator(CFTR).Elexacaftor(VX-445,Compound 1)facilitates the processing and trafficking of CFTR to increase the amount of CFTR at the cell surface.	price>
R-R-3787	Tulobuterol CAS No.41570-61-0	Tulobuterol (C-78 free base)/CAS No.41570-61-0 is a long-acting β2-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol is also a sympathomimetic agent used as a transdermal patch, and increases normal diaphragm muscle strength.	price>
R-C-2088	azd4635 CAS:1321514-06-0	AZD4635(HTL1071)is a potent,selective and orally active adenosine A2A receptor(A2AR)antagonist.AZD4635 binds to human A2AR with a Ki of 1.7nM and shows>30-fold selectivity over other adenosine receptors.	price>

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