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R-C-2120 CL2A-SN-38 CAS:1279680-68-0 CL2A-SN-38 is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate(ADC).CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types. price>
R-R-3820 A-61603 CAS No.107756-30-9 A-61603/CAS No.107756-30-9 is a selective α1A-adrenergic receptor agonist. A-61603 increases the frequency of spontaneous Ca2+ transients in rat ventricular myocytes in vitro. price>
R-C-2121 PK11007 CAS: 874146-69-7 PK11007 is a mild thiol alkylator with anticancer activity.PK11007 stabilizes p53 via selective alkylation of two surface-exposed cysteines without compromising its DNA binding activity.PK11007 induces mutant p53 cancer cell death by increasing reactive oxygen species (ROS)levels. price>
R-R-3821 Landiolol hydrochloride CAS No.144481-98-1 Landiolol hydrochloride (ONO1101 hydrochloride)/CAS No.144481-98-1 is a highly beta1 selective ultra-short acting beta-blocker (β1/β2 selectivity = 255:1, a half-life of 4 min), acts as an adrenoceptor antagonist. price>
R-C-2122 KY-226 CAS:1621673-53-7 KY-226 is a potent,selective,orally active and allosteric protein tyrosine phosphatase 1B(PTP1B)inhibitor with an IC50 of 0.25 μM,and without PPARγ agonist activity.KY-226 exerts anti-diabetic and anti-obesity effects by enhancing insulin and leptin signaling,respectively.KY-226 also protects neurons from cerebral ischemic injury. price>
R-R-3822 Meranzin CAS No.23971-42-8 Meranzin/CAS No.23971-42-8 is an absorbed bioactive compound from the Traditional Chinese Medicine (TCM) Chaihu-Shugan-San (CSS). Meranzin, isolated from leaves of Murraya exotica L., regulates the shared alpha 2-adrenoceptor and involves the AMPA-ERK1/2–BDNF signaling pathway. Meranzin has the potential for the prevention of the comorbidity of atherosclerosis and depression. price>
R-C-2123 LIT-001  CAS: 2245072-21-1 LIT-001 is the first nonpeptide oxytocin receptor(OT-R)agonist(EC50=55 nM;Ki=226nM).LIT-001 improves social interaction in a mouse model of autism. price>
R-R-3823 PVA/montmorillonite composite aerogel Polyvinyl alcohol/montmorillonite composite aerogel;PVA/montmorillonite composite aerogel from ruixi.Polyvinyl alcohol/montmorillonite composite aerogel is a lightweight, porous material that is created through a gelation process and subsequent removal of the liquid component, leaving behind a solid interconnected network of pores. This composite aerogel is a combination of polyvinyl alcohol (PVA) and montmorillonite clay, resulting in a material with unique properties that make it suitable for various applications.Applications of polyvinyl alcohol/montmorillonite composite aerogel include thermal insulation in buildings, lightweight structural components, oil spill cleanup materials, and as a component in advanced composites for aerospace and automotive industries, among others. price>
R-C-2124 JNK-IN-8 CAS:1410880-22-6 JNK-IN-8(JNK Inhibitor XVI)is the first irreversible JNK inhibitor for JNK1, JNK2 and JNK3 with IC50 of 4.7nM,18.7nM and 1nM,>10-fold selectivity against MNK2,Fms and no inhibition to c-Kit,Met,PDGFRβin A375 cell line. price>
R-R-3824 PVA/silica composite aerogel Polyvinyl alcohol/silica composite aerogel;PVA/silica composite aerogel;Polyvinyl alcohol/sio2 composite aerogel;PVA/sio2 composite aerogel from ruixi. Polyvinyl alcohol/silica composite aerogel is a remarkable material that combines the properties of polyvinyl alcohol (PVA) with those of silica to create a lightweight, highly porous substance with a wide range of applications. Applications of polyvinyl alcohol/silica composite aerogel include thermal insulation in buildings, lightweight structural components in aerospace and automotive industries, environmental cleanup materials, and as a medium for controlled drug release and biomedical scaffolding. price>
R-C-2125 INCB8761(PF-4136309) CAS:1341224-83-6 PF-4136309(INCB8761)is a potent,selective,and orally bioavailable antagonist of C-C chemokine receptor type 2(CCR2 or CD192(cluster of differentiation 192)with IC50 of 5.2nM,17nM and 13nM for human,mouse and rat CCR2,respectively. price>
R-R-3825 PVA/ZnO composite aerogel PVA/ZnO composite aerogel;Polyvinyl alcohol/zinc oxide composite aerogel;PVA/zinc oxide composite aerogel;Polyvinyl alcohol/ZnO composite aerogel from ruixi.Polyvinyl alcohol/zinc oxide (PVA/ZnO) composite aerogel is a remarkable material that combines the unique properties of polyvinyl alcohol (PVA) with those of zinc oxide to create a lightweight, porous substance with a wide range of potential applications. This composite aerogel is typically produced through a sol-gel process, followed by supercritical drying to remove the liquid component, resulting in a solid, interconnected porous structure.The combination of polyvinyl alcohol and zinc oxide in an aerogel composite offers a material with diverse properties, making it valuable in various industries and applications where lightweight, UV protection, antibacterial properties, and mechanical strength are desirable. price>
R-C-2126 LY900009 CAS:209984-68-9 LY900009 is a small molecule inhibitor of Notch signalling via selective inhibition of the γ-secretase protein.LY900009 inhibited plasma levels of amyloid-β peptide in a dose-dependent manner with 80-90% inhibition observed in the 30-to 60-mg cohorts. price>
R-R-3826 PVA/ZrO2 composite aerogel PVA/ZrO2 composite aerogel;Polyvinyl alcohol/ZrO2 composite aerogel;PVA/zirconia composite aerogel;Polyvinyl alcohol/zirconia composite aerogel from ruixi.Polyvinyl alcohol/zirconia composite aerogel is a remarkable material that combines the properties of polyvinyl alcohol (PVA) with zirconia, creating a lightweight, highly porous substance with a wide range of potential applications.The combination of polyvinyl alcohol and zirconia in an aerogel composite offers a material with diverse properties, making it valuable across various industries and fields that require lightweight, thermally insulating, mechanically robust, and chemically stable materials. price>
R-C-2127 BBT594 CAS:882405-89-2 BBT594(NVP-BBT594)is potent and selective RET and JAK2 inhibitor.NVP-BBT594 impairs GDNF-RET signaling and GDNF-dependent growth of MCF7-LTED cells.NVP-BBT594 targets GDNF-RET signaling and sensitizes MCF7-2A cells to letrozole treatment.GDNF-RET signaling as a rational therapeutic target may be useful to combat or delay the onset of AI resistance in breast cancer. price>
R-R-3827 PVA/Al2O3 composite aerogel PVA/Al2O3 composite aerogel;Polyvinyl alcohol/alumina composite aerogel;Polyvinyl alcohol/Al2O3 composite aerogel;PVA/alumina composite aerogel from ruixi.Polyvinyl alcohol/alumina (PVA/Al2O3) composite aerogel is a unique material that combines the characteristics of polyvinyl alcohol with those of alumina to produce a lightweight, porous substance with a wide array of potential applications. The composite aerogel is typically synthesized through a sol-gel process, followed by supercritical drying to eliminate the liquid component, resulting in a solid, interconnected porous structure.The combination of polyvinyl alcohol and alumina in an aerogel composite offers a material with diverse properties, making it valuable in various industries and fields that demand lightweight, thermally insulating, mechanically robust, chemically inert, and thermally stable materials. price>
R-C-2128 Olmutinib (BI 1482694) CAS:1353550-13-6 Olmutinib(BI 1482694)is a novel third-generation epidermal growth factor receptor(EGFR)mutation-specific tyrosine kinase inhibitor(TKI).Also a potent inhibitor of Bruton is tyrosine kinase. price>
R-R-3828 PVA/CNT composite aerogel PVA/CNT composite aerogel;Polyvinyl alcohol/carbon nanotube composite aerogel;PVA/carbon nanotube composite aerogel;Polyvinyl alcohol/CNT composite aerogel from ruixi. PVA/CNT composite aerogel is a remarkable material that combines the properties of polyvinyl alcohol (PVA) with carbon nanotube, creating a lightweight, highly porous substance with a wide range of potential applications.The combination of polyvinyl alcohol and carbon nanotube in an aerogel composite offers a material with diverse properties, making it valuable across various industries and fields that require lightweight, thermally insulating, mechanically robust, and chemically stable materials. price>
R-C-2129 NBQX CAS: 118876-58-7 NBQX(FG9202)is a highly selective and competitive AMPA receptor antagonist. NBQX has neuroprotective and anticonvulsant activity. price>
R-R-3829 PVA/ATP composite aerogel PVA/ATP composite aerogel;Polyvinyl alcohol/attapulgite composite aerogel;PVA/attapulgite composite aerogel;Polyvinyl alcohol/ATP composite aerogel from ruixi.Polyvinyl alcohol/attapulgite composite aerogel is a highly innovative material that combines the properties of polyvinyl alcohol (PVA) with attapulgite, resulting in a lightweight, porous substance with a diverse range of potential applications. The integration of polyvinyl alcohol with attapulgite in an aerogel composite yields a material with diverse properties, making it valuable across various industries and fields that demand lightweight, thermally insulating, mechanically robust, chemically stable, and adsorptive materials. price>