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R-C-2298 MCU-i4 CAS:371924-24-2 MCU-i4 is a negative modulator of the mitochondrial calcium uniporter (MCU)complex that directly binds a specific cleft in MICU1 and decreases mitochondrial Ca2+ influx. price>
R-R-3998 Azilsartan medoxomil CAS No.863031-21-4 Azilsartan medoxomil (TAK 491)/CAS No.863031-21-4 is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension. price>
R-C-2299 Amlodipine maleate CAS:88150-47-4 Amlodipine maleate is a dihydropyridine calcium channel blocker,acts as an orally active antianginal agent.Amlodipine maleate blocks the voltage-dependent L-type calcium channels,thereby inhibiting the initial influx of calcium. Amlodipine maleate can be used for the research of high blood pressure and cancer. price>
R-R-3999 Angiotensin II 5-valine CAS No.58-49-1 Angiotensin II 5-valine/CAS No.58-49-1 is an agonist of angiotensin receptor. price>
R-C-2300 Loureirin B CAS:119425-90-0 Loureirin B(LB,LrB),a flavonoid extracted from Dracaena cochinchinensis,is an inhibitor of PAI-1 with IC50 of 26.10μM.Loureirin B downregulates p-ERK and p-JNK in TGF-β1-stimulated fibroblasts.Loureirin B promotes insulin secretion mainly through increasing Pdx-1,MafA,intracellular ATP level,inhibiting the KATP current,influx of Ca2+ to the intracellular. price>
R-R-4000 Olmesartan medoxomil CAS No.144689-63-4 Olmesartan medoxomil/CAS No.144689-63-4 is a potent and selective angiotensin AT1 receptor inhibitor with IC50 of 66.2 μM. price>
R-C-2301 Ranolazine CAS:95635-55-5 Ranolazine(CVT 303)is an anti-angina drug that achieves its effects by inhibiting the late phase of inward sodium current(INa and IKr with IC50 values of 6μM and 12μM, respectively)without affecting heart rate or blood pressure(BP).Ranolazine is also a partial fatty acid oxidation(FAO)inhibitor.Antianginal agent. price>
R-R-4001 Benzyl benzoate CAS No.120-51-4 Benzyl benzoate (Phenylmethyl benzoate)/CAS No.120-51-4 is an orally active anti-scabies agent, acaricide (EC50= 0.06 g/m2) and fungicide. Benzyl benzoate is an angiotensin II (Ang II) inhibitor with antihypertensive effects. Benzyl benzoate can be used in perfumes, pharmaceuticals and the food industry. price>
R-C-2302 Isradipine CAS: 75695-93-1 Isradipine(PN 200-110)is an orally active L-type calcium channel blocker.Isradipine,as a powerful peripheral vasodilator,is a dihydropyridine calcium antagonist with selective actions on the heart as well as the peripheral circulation.Isradipine is a potentially viable neuroprotective agent for Parkinson is disease. price>
R-R-4002 2-(1,1-Dioxidobenzo[b]thien-3(2H)-ylidene)propanedinitrile CAS:74228-25-4 2-(1,1-Dioxidobenzo[b]thien-3(2H)-ylidene)propanedinitrile/CAS:74228-25-4 is an active pharmaceutical ingredient.It finds application in the synthesis of specific dyes, pharmaceutical intermediates(which can be used to prepare MOF ligands), and as a component in the formulation of adhesives or coatings. We can mass produce (kg level), process scaling up, pilot supply, raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time. price>
R-C-2303 Felodipine CAS:72509-76-3 Felodipine,a dihydropyridine,is a potent,vasoselective calcium channel antagonist.Felodipine lowers blood pressure(BP)by selective action on vascular smooth muscle,especially in the resistance vessels.Felodipine,an anti-hypertensive agent,induces autophagy.Felodipine can cross the blood-brain barrier. price>
R-R-4003 2-(6-Oxo-5,6-dihydro-4H-cyclopenta[C]thiophen-4-ylidene)malononitrile CAS :2099010-83-8 2-(6-Oxo-5,6-dihydro-4H-cyclopenta[C]thiophen-4-ylidene)malononitrile/CAS :2099010-83-8 is an active pharmaceutical ingredient.It finds application in the synthesis of specific dyes, pharmaceutical intermediates(which can be used to prepare MOF ligands), and as a component in the formulation of adhesives or coatings. We can mass produce (kg level), process scaling up, pilot supply, raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time. price>
R-C-2304 Manidipine CAS:89226-50-6 Manidipine is a calcium channel blocker(dihydropyridine type)that is used clinically as an antihypertensive.Manidipine is a lipophilic,third-generation dihydropyridine calcium channel antagonist with a high degree of selectivity for the vasculature,thereby inducing marked peripheral vasodilation with negligible cardiodepression.In addition,manidipine does not significantly affect norepinephrine levels,suggesting a lack of sympathetic activation. price>
R-R-4004 2-(6-Bromo-3-oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile CAS :507484-47-1 2-(6-Bromo-3-oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile/CAS :507484-47-1 is an active pharmaceutical ingredient.It finds application in the synthesis of specific dyes, pharmaceutical intermediates(which can be used to prepare MOF ligands), and as a component in the formulation of adhesives or coatings. We can mass produce (kg level), process scaling up, pilot supply, raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time. price>
R-C-2305 Nisoldipine CAS:63675-72-9 Nisoldipine(BAY-k 5552;Sular)is a calcium channel blocker belonging to the dihydropyridines class,specific for L-type Cav1.2 with IC50 of 10nM. price>
R-R-4005 2-(5,6-Dichloro-2,3-dihydro-3-oxo-1H-inden-1-ylidene)malononitrile CAS:2197167-50-1 The compound 2-(5,6-Dichloro-2,3-dihydro-3-oxo-1H-inden-1-ylidene)malononitrile/CAS:2197167-50-1 is a semiconductor that has been used for solar cells. The compound is an acceptor and the parameters of the thin film are determined by spectroscopic analysis. The solar cells have efficiencies of less than 10%. This material has been shown to be redshifted in the visible region of the electromagnetic spectrum and its efficiency is not high. The molecule is dipole with an average geometry. We can mass produce (kg level), process scaling up, pilot supply, raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time. price>
R-C-2306 Nimodipine CAS:66085-59-4 Nimodipine(BAY-e 9736)is an orally active,well-tolerated and light-sensitive dihydropyridine calcium antagonist.Nimodipine can be used for the research of cerebrovascular disorders. price>
R-R-4006 2-(6-Chloro-3-oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile CAS :507484-48-2 2-(6-Chloro-3-oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile/CAS :507484-48-2 is an active pharmaceutical ingredient.It finds application in the synthesis of specific dyes, pharmaceutical intermediates(which can be used to prepare MOF ligands), and as a component in the formulation of adhesives or coatings. We can mass produce (kg level), process scaling up, pilot supply, raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time. price>
R-C-2307 Nilvadipine CAS: 75530-68-6 Nilvadipine is a calcium channel blocker(CCB)used for the treatment of hypertension and chronic major cerebral artery occlusion.Pathohistochemical studies have revealed that the volume of the infarction in the middle cerebral artery occlusion model could be decreased by nilvadipine.Nilvadipine has also been studied as a possible treatment for Alzheimer is Disease. price>
R-R-4007 2-(5,6-Difluoro-3-oxo-2,3-dihydro-1h-inden-1-ylidene)malononitrile CAS :2083617-82-5 2-(5,6-Difluoro-3-oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile/CAS :2083617-82-5 is a molecule that has been found to be an acceptor in organic solar cells. It absorbs light and converts it into electricity using a process called photovoltaic conversion. The structure of this molecule allows for the absorption of sunlight from many angles, making it a more efficient solar cell. 2-(5,6-Difluoro-3-oxo-2,3-dihydro-1H-inden-1ylidene)malononitrile can be made in solution form and is stable at room temperature for long periods of time. This molecule is symmetric and has structural modifications that make it ideal for use as a donor or an acceptor in organic solar cells. We can mass produce (kg level), process scaling up, pilot supply, raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time. price>