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R-C-2376 Cephalexin CAS:15686-71-2 Cephalexin(Cefalexin;Cephacillin)is a potent,orally active and the first-generation cephalosporin antibiotic.Cephalexin kills gram-positive and some gram-negative bacteria by disrupting the growth of the bacterial cell wall.Cephalexin monohydrate is used for the research of pneumonia,strep throat,and bacterial endocarditis,et al. price>
R-R-4076 Bradykinin (1-5) CAS No.23815-89-6 Bradykinin (1-5)/CAS No.23815-89-6 is a major stable metabolite of Bradykinin, formed by the proteolytic action of angiotensin-converting enzyme (ACE). price>
R-C-2377 Oxytetracycline hydrochloride CAS:2058-46-0 Oxytetracycline Hydrochloride is the hydrochloride salt form of oxytetracycline, a tetracycline derivative produced by Streptomyces rimosus exhibiting antimicrobial activity.Oxytetracycline Hydrochloride is an antibacterial compound isolated from the elaboration products of the actinomycete, Streptomyces rimosus,when grown on a suitable medium.Oxytetracycline hydrochloride interferes with binding of aminoacyl-tRNA to the mRNA-ribosome complex,thereby preventing peptide elongation and inhibiting protein synthesis. It is often used to treat skin conditions. price>
R-C-3037 CZC24832 CAS:1159824-67-5 CZC24832 is the first selective PI3Kγ inhibitor with IC50 of 27 nM,with 10-fold selectivity over PI3Kβ and >100-fold selectivity over PI3Kα and PI3Kδ.Only for scientific research,not for human body. price>
R-R-4077 [Hyp3]-Bradykinin CAS No.37642-65-2 [Hyp3]-Bradykinin/CAS No.37642-65-2, naturally occurring peptide hormone, is a bradykinin receptor agonist. [Hyp3]-Bradykinin interacts with B2-bradykinin receptors and stimulates inositol phosphate production in cultured human fibroblasts. price>
R-C-2378 Aloperine CAS:56293-29-9 Aloperine is an alkaloid in sophora plants such as Sophora alopecuroides L,which has shown anti-cancer,anti-inflammatory and anti-virus properties. Aloperine is widely used to treat patients with allergic contact dermatitis eczema and other skin inflammation in China.Aloperine induces apoptosis and autophagy in HL-60 cells. price>
R-C-3038 AZD6482 CAS: 1173900-33-8 AZD6482 is a potent, selective and ATP competitive PI3Kβ inhibitor (IC(50) 0.01 μm). AZD6482 inhibited insulin-induced human adipocyte glucose uptake in vitro (IC(50) of 4.4 μm). Only for scientific research, not for human body. price>
R-R-4078 Rimonabant Hydrochloride CAS No.158681-13-1 Rimonabant Hydrochloride (SR 141716A Hydrochloride)/CAS No.158681-13-1 is a highly potent and selective central cannabinoid receptor (CB1) antagonist with an Ki of 1.8 nM. Rimonabant Hydrochloride (SR 141716A Hydrochloride) also inhibits Mycobacterial membrane protein Large 3 (MMPL3). price>
R-C-2379 Trimethoprim CAS:738-70-5 Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor.Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria.Trimethoprim has the potential for urinary tract infections,Shigellosis and Pneumocystis pneumonia treatment. price>
R-C-3039 GDC-0032 CAS:1282512-48-4 GDC-0032 is an orally bioavailable, potent and selective inhibitor of Class I PI3Kα, δ and γ isoforms, with 30 fold less inhibition of the PI3K β isoform relative to the PI3Kα isoform. GDC-0032 inhibits MCF7-neo/HER2 cells proliferation with IC50 of 2.5 nM. Only for scientific research, not for human body. price>
R-R-4079 2-Arachidonoylglycerol CAS No.53847-30-6 2-Arachidonoylglycerol/CAS No.53847-30-6 is a second endogenous cannabinoid ligand in the central nervous system. price>
R-C-2380 Sulfisoxazole CAS:127-69-5 Sulfisoxazole(Sulfafurazole),an endothelin receptor antagonist,is a sulfonamide antibacterial with an oxazole substituent.Sulfisoxazole inhibits breast cancer exosome release by targeting endothelin receptor A. price>
R-R-4080 JD-5037 CAS No.1392116-14-1 JD-5037/CAS No.1392116-14-1 is a potent CB1R antagonist with an IC50 of 1.5 nM. price>
R-C-2381 Bacitracin CAS:1405-87-4 Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy,which disrupts both gram positive and gram negative bacteria by interfering with cell wall and peptidoglycan synthesis. price>
R-R-4081 GW405833 hydrochloride CAS No.1202865-22-2 GW405833 hydrochloride/CAS No.1202865-22-2 is a potent and selective cannabinoid-2 (CB2) receptor agonist (EC50 = 0.65 nM; maximum inhibition = 44.6%). GW405833 hydrochloride produces potent antihyperalgesic effects in several rodent models of pain. price>
R-C-2382 K02288 CAS:1431985-92-0 K02288 is a potent bone morphogenetic protei(BMP)type I receptor inhibitor with IC50s of 1.8,1.1,6.4nM for ALK1,ALK2 and ALK6,respectively.K02288 shows slightly weaker inhibition against ALK3 and ALK6 with IC50s of of 5-34nM. price>
R-R-4082 Taranabant CAS No.701977-09-5 Taranabant/CAS No.701977-09-5 is a highly potent and selective cannabinoid 1 (CB1) receptor inverse agonist that inhibits the binding and functional activity of various agonists, with a binding Ki of 0.13 nM for the human CB1R in vitro. price>
R-R-4083 Pregnenolone monosulfate sodium CAS No.1852-38-6 Pregnenolone monosulfate sodium (3β-Hydroxy-5-pregnen-20-one monosulfate sodium)/CAS No.1852-38-6 is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate sodium can protect the brain from cannabis intoxication. Pregnenolone monosulfate sodium is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels. price>
R-R-4084 Olorinab CAS No.1268881-20-4 Olorinab (APD 371)/CAS No.1268881-20-4 is a highly potent, selective and fully efficacious cannabinoid receptor type 2 (CB2) agonist, with an EC50 of 6.2 nM for hCB2. price>
R-C-2385 Ruxolitinib (INCB018424) CAS:941678-49-5 Ruxolitinib(INCB018424)is the first potent,selective,JAK1/2 inhibitor to enter the clinic with IC50 of 3.3nM/2.8nM in cell-free assays,>130-fold selectivity for JAK1/2 versus JAK3.Ruxolitinib kills tumor cells through toxic mitophagy. Ruxolitinib induces autophagy and enhances apoptosis. price>