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Catalog	name	Description	price
R-R-4085	Yangonin CAS No.500-62-9	Yangonin/CAS No.500-62-9 exhibits affinity for the human recombinant cannabinoid CB1 receptor with an IC50 and a Ki of 1.79 μM and 0.72 μM, respectively.	price>
R-C-2386	Cucurbitacin I CAS：2222-07-3	Cucurbitacin-I(Elatericin B,JSI 124,NSC 521777),a natural cell-permeable triterpenoid isolated from Cucurbitaceae,is a novel selective inhibitor of JAK2/STAT3.	price>
R-R-4086	AM281 CAS No.202463-68-1	AM281/CAS No.202463-68-1 is a selective CB1 receptor antagonist with an IC50 of 9.91 nM. AM281 inhibits CB2 receptor with an IC50 of 13000 nM.	price>
R-C-2387	Propafenone CAS：54063-53-5	Propafenone(SA-79)is an orally active sodium channel blocking agent and a beta-adrenoceptor(β-adrenergic receptor)antagonist.Propafenone offers a broad spectrum of activity in the treatment of cardiac arrhythmias.	price>
R-R-4087	LY2828360 CAS No.1231220-79-3	LY2828360/CAS No.1231220-79-3 is a slowly acting but efficacious G protein-biased cannabinoid (CB2) agonist, inhibiting cAMP accumulation and activating ERK1/2 signaling.	price>
R-C-2388	Bisoprolol fumarate CAS:104344-23-2	Bisoprolol is a drug belonging to the group of beta blockers,a class of drugs used primarily in cardiovascular diseases.More specifically,it is a selective type β1 adrenergic receptor blocker.	price>
R-R-4088	Monlunabant CAS No.2712480-46-9	Monlunabant ((S)-MRI-1891)/CAS No.2712480-46-9 is a solid dispersions compound, as well as a cannabinoid CB1 receptor inhibitor.	price>
R-C-2389	Nebivolol CAS: 118457-14-0	Nebivolol is a beta-blocker.It works by affecting the response to nerve impulses in certain parts of the body,like the heart.As a result,the heart beats slower and decreases the blood pressure.When the blood pressure is lowered,the amount of blood and oxygen is increased to the heart.	price>
R-R-4089	(±)-Ibipinabant CAS No.362519-49-1	(±)-Ibipinabant ((±)-SLV319)/CAS No.362519-49-1 is the racemate of SLV319. (±)-Ibipinabant ((±)-SLV319) is a potent and selective cannabinoid-1 (CB-1) receptor antagonist with an IC50 of 22 nM.	price>
R-C-2390	Carvedilol Phosphate CAS:610309-89-2	Carvedilol Phosphate is the phosphate salt form of carvedilol,a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimetic activity.	price>
R-R-4090	CB1 antagonist 4 CAS No.1253641-65-4	CB1 antagonist 4 (compound 8)/CAS No.1253641-65-4 is a peripheral selective cannabinoid receptor type 1 (CB1) receptor antagonist. CB1 antagonist 4 shows limited penetrance to the brain in order to minimize or prevent CNS adverse reactions, and preserves potential antiobesity effects. CB1 antagonist 4 reduces propensity for psychiatric side effects.	price>
R-C-2391	Methyldopa CAS: 555-30-6	Methyldopa is a centrally acting antihypertensive agent.It is metabolized to alpha-methylnorepinephrine in the brain,and this compound activates central alpha-2 adrenergic receptors.Being a selective agonist for α2 adrenergic receptors,psychoactive drug is used as a sympatholytic or antihypertensive.	price>
R-R-4091	Org 27569 CAS No.868273-06-7	Org 27569/CAS No.868273-06-7 is a potent CB1 receptor allosteric modulator, which increases agonist binding, yet blocks agonist-induced CB1 signaling.	price>
R-C-2392	Dronedarone CAS:141626-36-0	Dronedarone(SR33589)is a derivative of amiodarone which is classified as a Class III antiarrhythmic agent.It shows rate-dependent inhibition of the rapid Na+ current,inhibits α and β-adrenergic receptors like Class II agents,exhibits blockade of K+ outward currents as the main mechanism of action of Class III, and effectively block slow Ca2+ inward currents(Class IV).	price>
R-R-4092	GW-405833 CAS No.180002-83-9	GW-405833 (L768242)/CAS No.180002-83-9 is a potent, selective cannabinoid receptor 2 (CB2) agonist with an EC50 of 50.7 nM. GW-405833 also behaves as a noncompetitive CB1 antagonist. GW-405833 suppresses inflammatory and neuropathic pain.	price>
R-C-2393	Pimozide CAS:2062-78-4	Pimozide(Orap,R6238)is an antagonist of Dopamine Receptors with Ki of 0.83nM,3.0 nM and 6600nM for dopamine D3,D2 and D1 receptors, respectively.Pimozide also exhibits binding affinity at α2-adrenoceptor and 5-HT1A with Ki of 360nM and 310nM,respectively.Pimozide is an antipsychotic drug with anti-tumor activity and suppresses STAT3 and STAT5 activity.	price>
R-R-4093	Leelamine hydrochloride CAS No.16496-99-4	Leelamine hydrochloride/CAS No.16496-99-4 is a tricyclic diterpene molecule that is extracted from the bark of pine trees. Leelamine hydrochloride is a cannabinoid receptor type 1 (CB1) agonist and a inhibitor of SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells that is not affected by androgen receptor status. Leelamine hydrochloride suppresses transcriptional activity of androgen receptor, which is known to regulate fatty acid synthesis[2,3].	price>
R-C-2394	Alfuzosin HCl CAS:81403-68-1	Alfuzosin HCl is a pharmaceutical drug of the alpha-1 blocker class.As an antagonist of the alpha-1 adrenergic receptor,it works by relaxing the muscles in the prostate and bladder neck,making it easier to urinate.It is thus used to treat benign prostatic hyperplasia(BPH).	price>
R-R-4094	MDA 19 CAS No.1048973-47-2	MDA 19/CAS No.1048973-47-2 is a potent and selective agonist of human cannabinoid receptor 2 (CB2), with a Ki of 43.3 nM. MDA 19 has antiallodynic effects in a rat model of neuropathic pain and does not affect rat locomotor activity.	price>
R-C-2395	Silodosin CAS:160970-54-7	Silodosin(KAD 3213;KMD 3213)is a potent,selective and orally active α1A-adrenergic receptor(α1A-AR)blocker.Silodosin is an effective and well-tolerated agent,it can be used for the investigation of LUTS/BPH.	price>

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