Xi'an ruixi Biological Technology Co

Home > Keywords >

Catalog	name	Description	price
R-R-4095	Virodhamine CAS No.287937-12-6	Virodhamine/CAS No.287937-12-6 is an endocannabinoid, it regulates neurotransmission by activating the cannabinoid (CB) receptors. Virodhamine is an antagonist of CB1 receptor and an agonist of CB2 receptor. Virodhamine induces megakaryocytic differentiation by triggering MAPK signaling and ROS production.	price>
R-C-2396	Nebivolol hydrochloride (R-65824) CAS:152520-56-4	Nebivolol hydrochloride selectively inhibits β1- adrenergic receptor with IC50 of 0.8nM.	price>
R-R-4096	Etrinabdione CAS No.1818428-24-8	Etrinabdione (EHP-101; VCE-004.8)/CAS No.1818428-24-8 is an orally active, specific PPARγ and CB2 receptor dual agonist. Etrinabdione inhibits prolyl-hydroxylases (PHDs) and activates the HIF pathway. Etrinabdione, a semi-synthetic multitarget cannabinoquinoid, has potent anti-inflammatory activity. Etrinabdione attenuates adipogenesis and prevents diet-induced obesity.	price>
R-C-2397	BMY 7378 Dihydrochloride CAS:21102-95-4	BMY 7378 is a multi-targeted inhibitor of α2C-adrenoceptor and α1D-adrenoceptor with pKi of 6.54 and 8.2,respectively,and acts as a mixed agonist and antagonist for 5-HT1A receptor with pKi of 8.3.	price>
R-R-4097	CB1 antagonist 2 CAS No.614726-85-1	CB1 antagonist 2/CAS No.614726-85-1 is caimabinoid 1 (CB1) antagonist extracted from patent WO2016184310A1, compound 3, inhibits CB1 in vivo with an IC50 of 25.5 nM.	price>
R-C-2398	Prazosin HCl CAS:19237-84-4	Prazosin hydrochloride is a well-tolerated,CNS-active α1-adrenergic receptor antagonist for the research of high blood pressure and alcohol use disorders. Prazosin hydrochloride potently inhibits Norepinephrine(NE)-stimulated 45Ca efflux with an IC50 of 0.15 nM.Prazosin hydrochloride inhibits organic cation transporters OCT-1 and OCT-3 with IC50s of 1.8, and 13μM,respectively.	price>
R-R-4098	Tedalinab CAS No.916591-01-0	Tedalinab (GRC-10693)/CAS No.916591-01-0 is a potent, orally active, and selective cannabinoid receptor 2 (CB2) agonist. Tedalinab has >4700-fold functional selectivity for CB2 over CB1. Tedalinab has potential for neuropathic pain and osteoarthritis treatment.	price>
R-C-2399	Naftopidil CAS:57149-07-2	Naftopidil(KT-611)is is a selective alpha1-adrenoceptor antagonist,with Kis of 3.7nM,20nM and 1.2nM for the cloned human α1a-,α1b-and α1d-adrenoceptor subtypes,respectively.Naftopidil has antiproliferative effects.Naftopidil can be used for the research of prostate hyperplasia.	price>
R-R-4099	Pregnenolone-d4-1 CAS No.61574-54-7	Pregnenolone-d4-1/CAS No.61574-54-7 is the deuterium labeled Pregnenolone. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels.	price>
R-C-2400	Timolol Maleate CAS:26921-17-5	(S)-Timolol Maleate(L-714,465 Maleate)is a non-cardioselective hydrophilic β-adrenoceptor blocker.(S)-Timolol Maleate is widely used as standard medication for intraocular pressure(glaucoma)by preventing the production of aqueous humor. (S)-Timolol Maleate can be used for hypertension,angina pectoris and myocardial infarction.	price>
R-R-4100	GAT211 CAS No.102704-40-5	GAT211/CAS No.102704-40-5 is a cannabinoid 1 receptor (CB1R) positive allosteric modulator (PAM). GAT211 activates cAMP and β-arrestin2 with EC50 values of 260 nM and 650 nM, respectively. GAT211 inhibits GAT211 can be used for neuropathic and/or inflammatory pain research.	price>
R-C-2401	Fargesin CAS:31008-19-2	Fargesin is a lignan from Magnolia fargesii,an oriental medicine used in the treatment of nasal congestion and sinusitis.Fargesin exhibits anti-inflammation effects on THP-1 cells via suppression of PKC pathway including downstream JNK, nuclear factors AP-1 and NF-ĸB.	price>
R-R-4101	CB2R PAM CAS No.2244579-87-9	CB2R PAM/CAS No.2244579-87-9 is an orally active cannabinoid type-2 receptors (CB2Rs) positive allosteric modulator. CB2R PAM displays antinociceptive activity in vivo in an experimental mouse model of neuropathic pain.	price>
R-C-2402	Dapiprazole Hydrochloride CAS:72822-13-0	Dapiprazole Hydrochloride(Glamidolo Hydrochloride,Reversil Hydrochloride)is the hydrochloride salt form of dapiprazole,an alpha-adrenergic blocker used to reverse mydriasis after eye examination.	price>
R-R-4102	CB1 agonist 1 CAS No.851212-80-1	CB1 agonist 1 (compound 22)/CAS No.851212-80-1 is an agonist of CB1. CB1 agonist 1 shows affinity to CB1 receptor with an pIC50 value of 5.7. CB1 agonist 1 can be used for the research of brain disorders.	price>
R-C-2403	Atipamezole CAS:104054-27-5	Atipamezole(MPV-1248,MPV1248,Antisedan)is a synthetic α2 adrenergic receptor antagonist.It has also been researched in humans as a potential anti-Parkinsonian drug.	price>
R-R-4103	Taranabant racemate CAS No.701977-00-6	Taranabant racemate (MK-0364 racemate)/CAS No.701977-00-6 is an antagonist and/or inverse agonist of the Cannabinoid-1 (CB1) receptor extracted from patent WO 2004048317 A1.	price>
R-C-2404	Piribedil CAS:3605-01-4	Piribedil(Trivastal,Trivastan)is a relatively selective dopamine(D2/D3)agonist with moderate antidepressant activity.It also has α2-adrenergic(α2A/α2C)antagonist properties.	price>
R-R-4104	SCH 336 CAS No.447459-51-0	SCH 336/CAS No.447459-51-0 is a potent, selective, inverse and orally active CB2 agonist. SCH 336 inhibits BaF3/CB2 migration. SCH 336 significantly inhibits the migration of leukocytes in vivo. SCH 336 blocks ovalbumin-induced lung eosinophilia in mice.	price>
R-C-2405	SR59230A CAS:174689-39-5	SR59230A is a blood-brain barrier penetrating,potent and selective antagonist of β3-adrenergic receptor with IC50 of 40nM,408nM,and 648nM for β3,β1,and β2 receptors,respectively.	price>

622623624625626627 628629630631632