Xi'an ruixi Biological Technology Co

Home > Keywords >

Catalog	name	Description	price
R-C-2446	Vorinostat (SAHA) CAS:149647-78-9	Vorinostat(suberanilohydroxamic acid)MK-0683 and SAHA,is a potent and selective inhibitor of histone deace tylases (HDACs).Vorinostat has been shown to bind to the active site of histone deacetylases and act as a chelator for Zinc ions also found in the active site of histone deacetylases.	price>
R-R-4146	NIDA-41020 CAS No.502486-89-7	NIDA-41020/CAS No.502486-89-7 is a potent and selective cannabinoid receptor 1(CB1) antagonist with a Ki of 4.1 nM. NIDA-41020 was designed as a potential radioligand for use in positron emission tomography (PET).	price>
R-C-2447	Tenuifolin CAS:20183-47-5	Tenuifolin,a secondary saponin isolated from hydrolysates of polygalasaponins, inhibits beta-amyloid synthesis in vitro and has nootropic activity in vivo via acetylcholine esterase inhibition and increases norepinephrine and dopamine production.	price>
R-R-4147	MJ15 CAS No.944154-76-1	MJ15/CAS No.944154-76-1 is a potent and selective CB1 receptor antagonist with a Ki of 27.2 pM and an IC50 of 118.9 pM for rat CB1 receptors. MJ15 exhibits potency in obesity and hyperlipidemia models. MJ15 inhibits food intake and increases in body weight in diet-induced obese rats and mice.	price>
R-C-2448	Acotiamide CAS:185106-16-5	Acotiamide(Acofide,Z388)is a novel acetylcholinesterase inhibitor with fundus-relaxing and gastroprokinetic properties.	price>
R-R-4148	GAT228 CAS No.1446648-15-2	GAT228/CAS No.1446648-15-2, the enantiomer of GAT211, is an allosteric cannabinoid receptor 1 (CB1) ligand.	price>
R-C-2449	AR-42 CAS：935881-37-1	AR-42((S)-HDAC-42):AR-42;NSC-736012;OSU-42;OSU-HDAC-42;OSUHDAC-42.AR-42 may possess additional histone-independent mechanisms,which may contribute to its superior profile in vitro and in vivo.	price>
R-R-4149	Pregnenolone (Standard) CAS No.145-13-1	Pregnenolone (Standard)/CAS No.145-13-1 is the analytical standard of Pregnenolone. This product is intended for research and analytical applications. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels.	price>
R-C-2450	M344 CAS：251456-60-7	M344(D 237)is an inhibitor of histone deacetylase(IC50=100nM)and an inducer of terminal cell fifferentiation.	price>
R-R-4150	N-Arachidonyldopamine-d8 CAS No.1159908-42-5	N-Arachidonyldopamine-d8/CAS No.1159908-42-5 is the deuterium labeled N-Arachidonyldopamine.	price>
R-C-2451	Ivermectin (MK-933) CAS： 70288-86-7	Ivermectin(MK-933)is a broad-spectrum anti-parasite agent.Ivermectin(MK-933)is a specific inhibitor of Impα/β1-mediated nuclear import and has potent antiviral activity towards both HIV-1 and dengue virus.It is a positive allosteric effector of P2X4 and the α7 neuronal nicotinic acetylcholine receptor(nAChRs).Ivermectin also inhibits bovine herpesvirus1(BoHV-1)replication and inhibits BoHV-1 DNA polymerase nuclear import.Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19.	price>
R-R-4151	RS 504393 CAS No.300816-15-3	RS 504393/CAS No.300816-15-3 is a selective CCR2 chemokine receptor antagonist (IC50 values are 89 nM and > 100 μM for inhibition of human recombinant CCR2 and CCR1 receptors respectively).	price>
R-C-2452	PNU-120596 CAS：501925-31-1	PNU-120596(NSC 216666)is a potent and selective α7 nAChR positive allosteric modulator(PMA)with an EC50 of 216 nM.PNU-120596 is inactive against α4β2, α3β4,and α9α10 nAChRs.PNU-120596 has the potential for psychiatric and neurological disorders research.	price>
R-R-4152	Bindarit CAS No.130641-38-2	Bindarit (AF2838)/CAS No.130641-38-2 is a selective inhibitor of the monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7, and MCP-2/CCL8, and no effect on other CC and CXC chemokines such as MIP-1α/CCL3, MIP-1β/CCL4, MIP-3/CCL23. Bindarit also has anti-inflammatory activity.	price>
R-C-2453	BNC210 CAS：13589-06-5	BNC210(H-Ile-Trp-OH;IW-2143)is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression.	price>
R-R-4153	INCB3344 CAS No.1262238-11-8	INCB3344/CAS No.1262238-11-8 is a potent, selective and orally bioavailable CCR2 antagonist with IC50 values of 5.1 nM (hCCR2) and 9.5 nM (mCCR2) in binding antagonism and 3.8 nM (hCCR2) and 7.8 nM (mCCR2) in antagonism of chemotaxis activity.	price>
R-C-2454	VU0238441 CAS：85511-68-8	VU0238441 is a pan muscarinic acetylcholine receptor(mAChR)positive allosteric modulator(PAM)with EC50s of 3.2 μM,2.8μM,2.2μM,2.1μM,>10μM for M1,M2,M3,M5 and M4,respectively.	price>
R-R-4154	Ilacirnon CAS No.1100318-47-5	CCX140 (CCX140-B)/CAS No.1100318-47-5 is a potent CCR2 antagonist.	price>
R-C-2455	VU0119498 CAS：79183-37-2	VU0119498 is a pan Gq mAChR M1,M3,M5 positive allosteric modulator(PAM), with EC50s of 6.04,6.38,and 4.08µM,respectively.VU0119498 has antidiabetic activity.	price>
R-R-4155	(1S)-CCR2 antagonist 1 CAS No.1683534-97-5	(1S)-CCR2 antagonist 1/CAS No.1683534-97-5 is a left-handed chiral body of CCR2 antagonist 1 (HY-112792). CCR2 antagonist 1 is a high-affinity and long-residence-time CCR2 antagonist, with a Ki of 2.4 nM.	price>

627628629630631632 633634635636637