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Catalog	name	Description	price
R-C-2456	benzylquinolone carboxylic acid CAS：338747-41-4	BQCA(benzylquinolone carboxylic acid)is a highly selective positive allosteric modulator of the M1 muscarinic acetylcholine receptor(mAChR).	price>
R-R-4156	RS102895 hydrochloride CAS No.1173022-16-6	RS102895 hydrochloride/CAS No.1173022-16-6 is a potent CCR2 antagonist, with an IC50 of 360 nM, and shows no effect on CCR1.	price>
R-C-2457	VU0238429 CAS：1160247-92-6	VU 0238429 is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5(mAChR5 or M5),with an EC50 of 1.16μM.	price>
R-R-4157	Cenicriviroc CAS No.497223-25-3	Cenicriviroc (TAK-652)/CAS No.497223-25-3 is an orally active, dual CCR2/CCR5 antagonist, also inhibits both HIV-1 and HIV-2, and displays potent anti-inflammatory and antiinfective activity.	price>
R-C-2458	JHU37152 CAS：2369979-67-7	JHU37152 is a potent and brain-penetrant DREADD agonist,with EC50s of 5 nM and 0.5 nM for hM3Dq and hM4Di DREADDs in HEK-293 cells,respectively. JHU37152 exhibits selective [3H]Clozapine displacement from DREADDs and not from other Clozapine-binding sites in mice brain tissue.	price>
R-R-4158	TAK-779 CAS No.229005-80-5	TAK-779/CAS No.229005-80-5 is a potent and selective nonpeptide antagonist of CCR5 and CXCR3, with a Ki of 1.1 nM for CCR5, and effectively and selectively inhibits R5 HIV-1, with EC50 and EC90 of 1.2 nM and 5.7 nM, respectively, in MAGI-CCR5 cells.	price>
R-C-2459	JHU37160 CAS：2369979-68-8	JHU37160 is a potent and brain-penetrant DREADD agonist,with EC50s of 18.5 nM and 0.2 nM for hM3Dq and hM4Di DREADDs in HEK-293 cells,respectively.JHU37160 exhibits selective Clozapine displacement from DREADDs and not from other Clozapine-binding sites in mice brain tissue.	price>
R-R-4159	Zelnecirnon CAS No.2366152-15-8	Zelnecirnon (RPT193)/CAS No.2366152-15-8 is an orally active inhibitor of CCR4, blocks the recruitment of Th2 inflammatory immune cells into inflamed tissues. Zelnecirnon can be used for allergic inflammation in atopic dermatitis, asthma, and other diseases research.	price>
R-C-2460	Varenicline Tartrate (CP 526555-18) CAS：375815-87-5	Varenicline Tartrate(CP 526555;Champix)is a nicotinic receptor partial agonist; it stimulates nicotine receptors more weakly than nicotine itself does.	price>
R-R-4160	CCR6 antagonist 1 CAS No.588674-64-0	CCR6 antagonist 1/CAS No.588674-64-0 is a CCR6 antagonist that inhibits the CCL20/CCR6 axis. CCR6 antagonist 1 can be used in the research of autoimmune-mediated inflammatory diseases, such as inflammatory bowel diseases (IBDs).	price>
R-C-2461	Bethanechol chloride CAS：590-63-6	Bethanechol chloride(Carbamyl-β-methylcholine chloride),a parasympathomimetic agent,is a mAChR agonist that exerts its effects via directly stimulating the mAChR(M1,M2,M3,M4,and M5)of the parasympathetic nervous system.	price>
R-R-4161	CCR6 inhibitor 1 CAS No.2437547-04-9	CCR6 inhibitor 1/CAS No.2437547-04-9 is a potent and selective CCR6 inhibitor, with IC50s of 0.45 and 6 nM for monkey and human CCR6, much more selective at CCR6 over human CCR1 (IC50, > 30000 nM), and CCR7 (IC50, 9400 nM). CCR6 inhibitor 1 markedly blocks ERK phosphorylation. CCR6 inhibitor 1 is used in the research of autoimmune diseases and cancer.	price>
R-C-2462	Pilocarpine HCl CAS：54-71-7	Pilocarpine Hydrochloride is a potent M3-type muscarinic acetylcholine receptor(M3 muscarinic receptor)agonist.	price>
R-R-4162	AZD2098 CAS No.566203-88-1	AZD2098/CAS No.566203-88-1 is a potent and selective CC-chemokine receptor 4 (CCR4) inhibitor with pIC50s of 7.8, 8.0, 8.0 and 7.6 for human, rat, mouse and dog respectively, used for asthma research.	price>
R-C-2463	Nitenpyram CAS:150824-47-8	Nitenpyram is a calss of neonicotinoid and an insect nicotinic acetylcholine receptor(nAChR)agonist with an IC50 of 14nM.Nitenpyram is an oral fast-acting insecticide used to suppress sucking insects on companion animals.	price>
R-R-4163	ZK756326 dihydrochloride CAS No.1780259-94-0	ZK756326 dihydrochloride/CAS No.1780259-94-0 is a nonpeptide chemokine receptor agonist for the CC chemokine receptor CCR8.	price>
R-C-2464	LY2119620 CAS:886047-22-9	LY2119620 is a positive allosteric modulator of the M2 and M4 muscarinic acetylcholine receptors(mAChRs).	price>
R-R-4164	AZ084 CAS No.929300-19-6	AZ084/CAS No.929300-19-6 is a potent, selective, allosteric and oral active CCR8 allosteric antagonist, with a Ki of 0.9 nM. Has potential to treat asthma. AZ084 restrains the formation of the immunologically tolerant pre-metastatic niche (PMN) and tumor cells metastasis in lung by downregulating Treg differentiation. AZ084 can be used in studies of asthma and cancer.	price>
R-C-2465	Cytisine CAS:485-35-8	Cytisine(Baphitoxine,Sophorine)is a nicotinic acetylcholine receptor agonist.	price>
R-R-4165	BX471 hydrochloride CAS No.288262-96-4	BX471 hydrochloride (ZK-811752 hydrochloride)/CAS No.288262-96-4 is a potent, selective non-peptide CCR1 antagonist with Ki of 1 nM for human CCR1, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.	price>

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