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Catalog	name	Description	price
R-R-4237	Plerixafor octahydrochloride CAS No.155148-31-5	Plerixafor octahydrochloride (AMD3100 octahydrochloride)/CAS No.155148-31-5 is a selective CXCR4 antagonist with an IC50 of 44 nM.	price>
R-C-2538	Tofogliflozin(CSG 452) CAS：1201913-82-7	Tofogliflozin(CSG-452)is a potent and highly specific sodium/glucose cotransporter 2(SGLT2)inhibitor with Ki values of 2.9,14.9,and 6.4nM for human, rat,and mouse SGLT2.	price>
R-R-4238	Navarixin CAS No.473727-83-2	Navarixin (SCH 527123)/CAS No.473727-83-2 is a CXCR1 and CXCR2 antagonist that is potent, allosteric, and orally active, with Kd values of 41 nM for cynomolgus CXCR1 and 0.20 nM, 0.20 nM, 0.08 nM for mouse, rat and cynomolgus monkey CXCR2, respectively.	price>
R-C-2539	Plerixafor（ AMD310） CAS：110078-46-1	Plerixafor(AMD 3100)is a selective CXCR4 antagonist with an IC50 of 44nM.Plerixafor,an immunostimulant and a hematopoietic stem cell(HSC)mobilizer, is an allosteric agonist of CXCR7.Plerixafor inhibits HIV-1 and HIV-2 replication with an EC50 of 1-10nM.	price>
R-R-4239	AZD-5069 CAS No.878385-84-3	AZD-5069/CAS No.878385-84-3 is a potent CXCR2 chemokine receptor antagonist, used for caner treatment.	price>
R-C-2540	Ki16198 CAS：355025-13-7	Ki16198 is a potent and orally active LPA receptor antagonist,the methyl ester of Ki16425(HY-13285).Ki16198 inhibits LPA1 and LPA3-induced inositol phosphate production with Ki values of 0.34μM and 0.93μM,respectively.Ki16198 is effective for pancreatic cancer tumorigenesis and metastasis in vivo.	price>
R-R-4240	Mavorixafor trihydrochloride CAS No.2309699-17-8	Mavorixafor trihydrochloride (AMD-070 trihydrochloride)/CAS No.2309699-17-8 is a potent, selective and orally available CXCR4 antagonist, with an IC50 value of 13 nM against CXCR4 125I-SDF binding, and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs with an IC50 of 1 and 9 nM, respectively.	price>
R-C-2541	Oxiracetam CAS：62613-82-5	Oxiracetam is a cyclic derivative of γ-aminobutyric acid(GABA)which has been commonly used as nootropic drug to treat cognitive impairments.	price>
R-R-4241	SCH 546738 CAS No.906805-42-3	SCH 546738/CAS No.906805-42-3 is a potent, orally active and non-competitive CXCR3 antagonist, the affinity constant (Ki) of SCH 546738 binding to human CXCR3 receptor is determined to be 0.4 nM in multiple experiments.	price>
R-C-2542	Prasugrel CAS：150322-43-3	Prasugrel(PCR 4099),a thienopyridine and prodrug,inhibits platelet function.Prasugrel is an orally active and potent P2Y12 receptor antagonist,and inhibits ADP-induced platelet aggregation.	price>
R-R-4242	SX-682 CAS No.1648843-04-2	SX-682/CAS No.1648843-04-2 is an orally bioavailable, potent allosteric inhibitor of CXCR1 and CXCR2. SX-682 can block tumor myeloid-derived suppressor cells (MDSCs) recruitment and enhance T cell activation and antitumor immunity.	price>
R-C-2543	Agomelatine (S-20098) CAS:138112-76-2	Agomelatine(S-20098)is a specific agonist of MT1 and MT2 receptors with Kis of 0.1,0.06,0.12, and 0.27nM for CHO-hMT1,HEK-hMT1,CHO-hMT2,and HEK-hMT2,respectively.Agomelatine is a selective 5-HT2C receptor antagonist with pKis of 6.4 and 6.2 at native(porcine)and cloned, human 5-HT2C receptors, respectively.	price>
R-R-4243	ACT-1004-1239 CAS No.2178049-58-4	ACT-1004-1239/CAS No.2178049-58-4 is a potent, selective, orally active CXCR7 antagonist with an IC50 value of 3.2 nM.	price>
R-C-2544	Escitalopram oxalate CAS:219861-08-2	Escitalopram Oxalate is a furancarbonitrile that is one of the selective serotonin uptake inhibitors used as an antidepressant.As a selective serotonin reuptake inhibitor(SSRI),escitalopram blocks the reuptake of serotonin by neurons in the central nervous system(CNS),thereby potentiating CNS serotonergic activity.	price>
R-R-4244	NUCC-390 dihydrochloride CAS No.2749281-71-6	NUCC-390 dihydrochloride/CAS No.2749281-71-6 is a novel and selective small-molecule CXCR4 receptor agonist. NUCC-390 dihydrochloride induces internalization of CXCR4 receptors and acts in an opposite way of AMD3100 (HY-10046). NUCC-390 dihydrochloride promotes nerve recovery of function after neurodegeneration in vivo.	price>
R-C-2545	Clemizole CAS:442-52-4	Clemizole is an H1 histamine receptor antagonist,is found to substantially inhibit HCV replication.The IC50 of Clemizole for RNA binding by NS4B is 24±1nM,whereas its EC50 for viral replication is 8µM.	price>
R-R-4245	SB-265610 CAS No.211096-49-0	SB-265610/CAS No.211096-49-0 is a selective, competitive, nonpeptide and allosteric CXCR2 antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization and neutrophil chemotaxis with IC50s of 3.7 nM and 70 nM, respectively.	price>
R-C-2546	J147 CAS:1146963-51-0	J-147 is an exceptionally potent,orally active, neuroprotective agent for cognitive enhancement.J-147 can readily pass the blood brain barrier(BBB).J-147 can inhibit monoamine oxidase B(MAO B)and the dopamine transporter with EC50 values of 1.88μM and 0.649μM,respectively.	price>
R-R-4246	CXCR7 antagonist-1 CAS No.1613021-99-0	CXCR7 antagonist-1/CAS No.1613021-99-0 is a CXCR7 antagonist that inhibits the binding of the SDF-1 chemokine (also known as the CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7. CXCR7 antagonist-1 is useful in preventing tumor cell proliferation, tumor formation, inflammatory diseases, and many other diseases (extracted from patent WO2014085490A1, compound 1.128).	price>
R-C-2547	NS11394 CAS:951650-22-9	NS-11394 is a drug which acts as a subtype-selective positive allosteric modulator at GABAA receptors,with selectivity for the α3 and α5 subtypes. NS11394 has a unique subtype-selective GABA(A)receptor profile and represents an excellent pharmacological tool to further understanding on the relative contributions of GABA(A)receptor subtypes in various therapeutic areas.	price>

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