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Catalog	name	Description	price
R-C-2609	TLQP 21 CAS:869988-94-3	TLQP-21,a VGF-derived peptide endowed of endocrine and extraendocrine properties,is a potent G-protein-coupled receptor complement-3a receptor 1(C3aR1)agonist(EC50:mouse TLQP-21=10.3μM;human TLQP-21=68.8μM).TLQP-21 activates C3aR1 to induce an increase of intracellular Ca2+.TLQP-21 is used for the research in regulation of nociception and other relevant physiologic functions.	price>
R-R-4309	3-O-Methyldopa CAS No.300-48-1	3-O-Methyldopa (3-Methoxy-L-tyrosine)/CAS No.300-48-1 is a metabolite of L-DOPA which is formed by catechol-O-methyltransferase (COMT). 3-O-Methyldopa competitively inhibits the pharmacodynamics of l-DOPA and dopamine.	price>
R-C-2610	YM155 (Sepantronium Bromide) CAS:781661-94-7	YM155(Sepantronium Bromide)is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0.54nM in HeLa-SURP-luc and CHO-SV40-luc cells;does not significantly inhibit SV40 promoter activity,but is observed to slightly inhibit the interaction of Survivin with XIAP.	price>
R-R-4310	Droperidol CAS No.548-73-2	Droperidol/CAS No.548-73-2 is a butyrophenone-type Dopamine-2 receptor antagonist.	price>
R-C-2611	SC-10 CAS:102649-79-6	SC-10 is a PKC activator.It acts by stimulating PKC mediated myosin light chain phosphorylation without activating MLC kinase.	price>
R-R-4311	Loxapine succinate CAS No.27833-64-3	Loxapine succinate/CAS No.27833-64-3 is an orally active dopamine inhibitor, 5-HT receptor antagonist and also a dibenzoxazepine anti-psychotic agent. Loxapine can also suppresses bacterial efflux pump activity and inhibit intracellular multiple-antibiotic-resistant Salmonella enterica serovar Typhimurium in macrophages.	price>
R-C-2612	ML347 CAS:1062368-49-3	ML347(DN193719)is a highly selective ALK1/ALK2 inhibitor with IC50s of 46/32nM; shows>300-fold selectivity for ALK2 vs.	price>
R-R-4312	Nomifensine CAS No.24526-64-5	Nomifensine/CAS No.24526-64-5 is a norepinephrine-dopamine reuptake inhibitor, increases the amount of synaptic norepinephrine and dopamine available to receptors by blocking the dopamine and norepinephrine reuptake transporters.	price>
R-C-2613	SR-3677 CAS:1072959-67-1	SR-3677 is a novel,potent and highly selective inhibitor of Rho Kinase(ROCK-II) with the IC50 value of ~0.3nM in enzyme and cell based assays.	price>
R-R-4313	A68930 hydrochloride CAS No.130465-39-3	A68930 hydrochloride/CAS No.130465-39-3, as a dopamine D1 receptor agonist, can be used for the research of bronchiectasis.	price>
R-C-2614	DMH-1 CAS:1206711-16-1	DMH-1 is a potent and selective BMP inhibitor with IC50s of 27/107.9/<5/47.6 nM for ALK1/ALK2/ALK3/ALK6,respectively.	price>
R-R-4314	Amisulpride CAS No.71675-85-9	Amisulpride/CAS No.71675-85-9 is a dopamine D2/D3 receptor antagonist with Kis of 2.8 and 3.2 nM for human dopamine D2 and D3, respectively.	price>
R-C-2615	Midostaurin (PKC412) CAS:120685-11-2	Midostaurin(PKC412;CGP 41251)is a multi-targeted protein kinase inhibitor which inhibits PKCα/β/γ,Syk,Flk-1,Akt,PKA,c-Kit,c-Fgr,c-Src,FLT3,PDFRβ and VEGFR1/2 with IC50s ranging from 22-500nM.	price>
R-R-4315	Clebopride malate CAS No.57645-91-7	Clebopride malate/CAS No.57645-91-7 is a dopamine antagonist drug with antiemetic and prokinetic properties used to treat functional gastrointestinal disorders.	price>
R-C-2616	Calphostin C CAS:121263-19-2	The calphostins are a class of closely related chemical compounds isolated from the fungus Cladosporium cladosporioides.The known calphostins include calphostin A,calphostin B,calphostin C,calphostin D,and calphostin I.The calphostins are inhibitors of protein kinase C(PKC).	price>
R-R-4316	Nomifensine maleate CAS No.32795-47-4	Nomifensine maleate/CAS No.32795-47-4 is a selective inhibitor of dopamine uptake, used in adult attention deficit disorder.	price>
R-C-2617	PKC fragment (530-558)	Potent activator of protein kinase C(Ka~10 mM);corresponds to residues 530-558 of the catalytic domain of PKC.	price>
R-R-4317	Pridopidine CAS No.346688-38-8	Pridopidine/CAS No.346688-38-8, a dopamine (DA) stabilizer, acts as a low affinity dopamine D2 receptor (D2R) antagonist. Pridopidine exerts high affinity towards sigma 1 receptor (S1R) with Ki between 70 and 80 nM, which is ~100× higher than its affinity toward D2R.	price>
R-C-2618	Ro 31-8220 Mesylate CAS:138489-18-6	Ro 31-8220 is a PKC-inhibitor,which inhibits stimulated fluid pinocytosis of human PMNs induced by the PKC-activators phorbol myristate acetate (PMA,IC50=1.35 x 10(-6)M)or diacylglycerols(OAG,diC8)by 95%.Ro-31-8220 showed the apoptotic effect on HL-60 cells,which was mediated by a well-characterized transduction process of apoptotic signals:i.e.,mitochondrial cytochrome c efflux and the activation of caspase-3 in the cytosol.	price>
R-R-4318	Dexpramipexole dihydrochloride CAS No.104632-27-1	Dexpramipexole dihydrochloride ((R)-Pramipexole dihydrochloride)/CAS No.104632-27-1 is a neuroprotective agent and weak non-ergoline dopamine agonist.	price>

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