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R-R-4343 Quinelorane dihydrochloride CAS No.97548-97-5 Quinelorane dihydrochloride (LY163502)/CAS No.97548-97-5 is a potent dopamine D3/D2 receptor agonist. Quinelorane has the potential for neurological and psychiatric disorders research. price>
R-C-2644 Z-DEVD-FMK CAS:210344-95-9 Z-DEVD-FMK(Caspase-3 Inhibitor)is a specific,irreversible Caspase-3 inhibitor,and also shows potent inhibition on caspase-6,caspase-7,caspase-8, and caspase-10. price>
R-R-4344 (Rac)-PF-06256142 CAS No.1609580-97-3 (Rac)-PF-06256142/CAS No.1609580-97-3 is the less effective enantiomer of PF-06256142 (HY-119943). (Rac)-PF-06256142 is an agonist of D1 receptor, with an EC50 of 107 nM. price>
R-C-2645 Z-IETD-FMK CAS:210344-98-2 Z-IETD-FMK(Z-IE(OMe)TD(OMe)-FMK)is a selective and cell permeable caspase-8 inhibitor.Z-IETD-FMK is also a granzyme B inhibitor. price>
R-R-4345 Carmoxirole hydrochloride CAS No.115092-85-8 Carmoxirole hydrochloride (EMD 45609 hydrochloride)/CAS No.115092-85-8 is a selective, peripherally acting dopamine D2 receptor agonist and exhibits antihypertensive activities in vivo. price>
R-C-2646 Z-WEHD-FMK CAS:210345-00-9 Z-WEHD-FMK is a potent,cell-permeable and irreversible caspase-1/5 inhibitor.Z-WEHD-FMK also exhibits a robust inhibitory effect on cathepsin B activity (IC50=6μM).Z-WEHD-FMK can be used to investigate cells for evidence of apoptosis. price>
R-R-4346 Acetophenazine dimaleate CAS No.5714-00-1 Acetophenazine dimaleate/CAS No.5714-00-1, a phenothiazine derivative, is an antipsychotic agent. Acetophenazine dimaleate primarily blocks dopamine D2 receptors in the brain. Acetophenazine dimaleate can be used for researching psychotic disorders such as schizophrenia and anxious depression. price>
R-C-2647 Ac-LEHD-AFC Ac-LEHD-AFC,fluorogenic caspase substrate.Analog of the caspase-9 substrate, LEHD-AFC. price>
R-R-4347 UCM-1306 CAS No.2258608-78-3 UCM-1306/CAS No.2258608-78-3 is a potent and orally active human dopamine D1 receptor allosteric modulator (PAM). UCM-1306 increases the endogenous dopamine (DA) maximal effect both in human and mouse D1 receptors. UCM-1306 is not only for improving motor symptoms but also for addressing the key comorbid cognitive impairment associated with long-term Parkinson disease (PD). price>
R-C-2648 Gambogic acid CAS:2752-65-0 Gambogic Acid(Beta-Guttiferrin)is derived from the gamboges resin of the tree Garcinia hanburyi.Gambogic Acid (Beta-Guttiferrin)inhibits Bcl-XL,Bcl-2,Bcl-W,Bcl-B,Bfl-1 and Mcl-1 with IC50s of 1.47μM,1.21μM,2.02 μM,0.66μM,1.06μM and 0.79μM. price>
R-R-4348 L-745870 hydrochloride CAS No.1173023-36-3 L-745870 hydrochloride/CAS No.1173023-36-3 is a potent, selective, brain-penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. L-745870 hydrochloride shows weaker affinity for D2 (Ki of 960 nM) and D3 (Ki of 2300 nM) receptors, and exhibits moderate affinity for 5-HT2 receptors, sigma sites and α-adrenoceptors. price>
R-R-4349 Trimethobenzamide hydrochloride CAS No.554-92-7 Trimethobenzamide hydrochloride/CAS No.554-92-7 is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting. price>
R-C-2650 Necrostatin-1 CAS:4311-88-0 Necrostatin-1(Nec-1)is a specific RIP1(RIPK1)inhibitor and inhibits TNF-α-induced necroptosis with EC50 of 490 nM in 293T cells.Necrostatin-1 also blocks IDO and suppresses autophagy and apoptosis. price>
R-R-4350 ML417 CAS No.1386162-69-1 ML417/CAS No.1386162-69-1 is a selective and brain penetrant D3 dopamine receptor (D3R) agonist, with an EC50 of 38 nM. ML417 potently promotes D3R-mediated β-arrestin translocation, G protein mediated signaling, and pERK phosphorylation with minimal effects on other GPCR-mediated signaling. ML417 exhibits neuroprotection against toxin-induced neurodegeneration of dopaminergic neurons. price>
R-C-2651 Pifithrin-β CAS:60477-34-1 Pifithrin-β(PFT β)is a potent p53 inhibitor with an IC50 of 23μM. price>
R-R-4351 SKF 77434 hydrobromide CAS No.300561-58-4 SKF 77434 hydrobromide/CAS No.300561-58-4 is a selective dopamine D1 receptor partial agonist. SKF 77434 hydrobromide has the potential to study cocaine addiction. price>
R-C-2652 CAY10603 CAS:1045792-66-2 CAY10603(BML-281)is a potent and selective HDAC6 inhibitor,with an IC50 of 2 pM;CAY10603(BML-281)also inhibits HDAC1,HDAC2,HDAC3,HDAC8,HDAC10,with IC50s of 271,252,0.42,6851,90.7nM. price>
R-R-4352 L-Stepholidine CAS No.16562-13-3 L-Stepholidine (Stepholidine)/CAS No.16562-13-3 exhibits mixed dopamine D1 receptor agonist and D2 antagonist properties. L-Stepholidine has neuroprotective effect and inhibits Heroin-induced reinstatement. L-Stepholidine is a potential medication for the research of opiate addiction. price>
R-C-2653 Mupirocin CAS:12650-69-0 Mupirocin(BRL-4910A)is an orally active antibiotic isolated from Pseudomonas fluorescens.Mupirocin(BRL-4910A)apparently exerts its antimicrobial activity by reversibly inhibiting isoleucyl-transfer RNA,thereby inhibiting bacterial protein and RNA synthesis. price>
R-R-4353 MLS1082 CAS No.883958-36-9 MLS1082/CAS No.883958-36-9 is a pyrimidone-based D1-like dopamine receptor positive allosteric modulator, with an EC50 of 123 nM for DA-stimulated G protein signaling. price>