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Catalog	name	Description	price
R-C-2708	CBB1003 CAS:1379573-88-2	CBB1003 is a novel histone demethylase LSD1 inhibitor with IC50 of 10.54uM.	price>
R-R-4408	PG01037 dihydrochloride CAS No.675599-62-9	PG01037 (dihydrochloride)/CAS No.675599-62-9 is a potent and selective dopamine D3 receptor antagonist with a Ki of 0.7 nM.	price>
R-C-2709	CBB1007 CAS:1379573-92-8	CBB1007 is a cell-permeable amidino-guanidinium compound that acts as a potent,reversible and substrate competitive LSD1 selective inhibitor (IC50=5.27μM for hLSD1).	price>
R-R-4409	Cabergoline-d6 CAS No.2738376-76-4	Cabergoline-d6 is deuterium labeled Cabergoline. Cabergoline is an ergot derived-dopamine D2-like receptor agonist that has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively).	price>
R-C-2710	YM 750 CAS:138046-43-2	YM-750 is a potent acyl-CoA:cholesterol acyltransferase(ACAT)inhibitor(IC50=0.18 μM).ACAT catalyzes the formation of cholesteryl esters from cholesterol and long-chain fatty-acyl-coenzyme A.	price>
R-R-4410	OS-3-106 CAS No.1580000-17-4	OS-3-106/CAS No.1580000-17-4 is a potent, BBB-penetrated and selective dopamine D3 receptor (D3R) agonist. OS-3-106 binds with high affinity (Ki = 0.2 nM) at the D3R. OS-3-106 can be used for psychoactivator addiction research.	price>
R-C-2711	GSK J5 CAS:1394854-51-3	Inactive isomer of GSK J4;also cell permeable ester derivative of the inactive control,GSK J2.	price>
R-R-4411	Clomipramine-d3 hydrochloride CAS No.1398065-86-5	Clomipramine-d3 (hydrochloride)/CAS No.1398065-86-5 is a deuterium labeled Clomipramine hydrochloride. Clomipramine hydrochloride is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively.	price>
R-C-2712	WZ4002 CAS:1213269-23-8	WZ4002 is a mutant selective EGFR inhibitor with IC50s of 2,8,3 and 2nM for EGFRL858R,EGFRL858R/T790M,EGFRE746-A750 and EGFRE746-A750/T790M,respectively.	price>
R-R-4412	Fluphenazine-d8 CAS No.1323633-98-2	Fluphenazine-d8/CAS No.1323633-98-2 is the deuterium labeled Fluphenazine. Fluphenazine is a potent, orally active phenothiazine-based dopamine receptor antagonist. Fluphenazine blocks neuronal voltage-gated sodium channels. Fluphenazine acts primarily through antagonism of postsynaptic dopamine-2 receptors in mesolimbic, nigrostriatal, and tuberoinfundibular neural pathways. Fluphenazine can antagonize Methylphenidate-induced stereotyped gnawing and inhibit climbing behaviour in mice. Fluphenazine can be used for researching psychosis and painful peripheral neuropathy associated with diabetes and has potential to inhibit SARS-CoV-2.	price>
R-C-2713	WZ8040 CAS:1214265-57-2	WZ8040 is an irreversible mutated EGFR T790M inhibitor and inhibits EGFR phosphorylation.WZ8040 displays 100-fold greater activity against the mutated EGFR than the normal.	price>
R-R-4413	Sonepiprazole CAS No.170858-33-0	Sonepiprazole (PNU-101387G)/CAS No.170858-33-0 is a selective D4 dopamine antagonist with Kis of 3.6, 10.1, 5147, and 7430 nM for rD4-Dopamine, hD4.2-Dopamine, rD2-Dopamine, and Histamine-H1 receptors, respectively.	price>
R-C-2714	BMS-911543 CAS:1271022-90-2	BMS-911543 is an orally available small molecule targeting a subset of Janus-associated kinase(JAK)with potential antineoplastic activity.JAK2 inhibitor BMS-911543 selectively inhibits JAK2,thereby preventing the JAK/STAT(signal transducer and activator of transcription)signaling cascade,including activation of STAT3.This may lead to an induction of tumor cell apoptosis and a decrease in cellular proliferation.	price>
R-R-4414	Haloperidol-d4-1 CAS No.136765-35-0	Haloperidol-d4-1/CAS No.136765-35-0 is deuterium labeled haloperidol, and the latter is a potent dopamine D2 receptor antagonist.	price>
R-C-2715	AZD-9291 (Osimertinib) CAS:1271022-90-2	AZD-9291 is a third-generation EGFR inhibitor,showed promise in preclinical studies and provides hope for patients with advanced lung cancers that have become resistant to existing EGFR inhibitors.	price>
R-R-4415	Dexpramipexole-d3 dihydrochloride CAS No.1432230-09-5	Dexpramipexole-d3 (dihydrochloride)/CAS No.1432230-09-5 is the deuterium labeled Dexpramipexole. Dexpramipexole((R)-Pramipexole), also known as R-(+)-Pramipexole, is a neuroprotective agent and weak non-ergoline dopamine agonist.	price>
R-C-2716	FASN-IN-1 CAS:1808260-84-5	FASN-IN-1 is a fatty acid synthase(FASN)inhibitor extracted from patent WO2015134790A1,compound 56.	price>
R-R-4416	Molindone-d8 CAS No.1189805-13-7	Molindone-d8/CAS No.1189805-13-7 is the deuterium labeled Molindone. Molindone hydrochloride (EN-1733A) is a therapeutic antipsychotic, used in the treatment of schizophrenia, works by blocking the effects of dopamine in the brain, leading to diminished psychoses.	price>
R-C-2717	OSI-420 CAS:183320-51-6	OSI-420(Desmethyl Erlotinib,CP-473420)is an orally active EGFR tyrosin kinase inhibitor,which inhibits receptor tyrosine kinases(TKs)by inhibition of the intercellular domain .	price>
R-R-4417	Raclopride-d5 hydrochloride CAS No.1217623-85-2	Raclopride-d5 (hydrochloride)/CAS No.1217623-85-2 is the deuterium labeled Raclopride. Raclopride is a dopamine D2/D3 receptor antagonist, which binds to D2 and D3 receptors with dissociation constants (Kis) of 1.8 nM and 3.5 nM, respectively, but has a very low affinity for D1 and D4 receptors with Kis of 18000 nM and 2400 nM, respectively.	price>

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