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Catalog	name	Description	price
R-R-4425	AZD1390 CAS No.2089288-03-7	AZD1390/CAS No.2089288-03-7 is a potent, highly selective, orally bioavailable, brain-penetrant ATM inhibitor with an IC50 of 0.78 nM in cell.	price>
R-R-4426	Camonsertib CAS No.2417489-10-0	Camonsertib (RP-3500)/CAS No.2417489-10-0 is an orally active, selective ATR kinase inhibitor (ATRi) with an IC50 of 1.00 nM in biochemical assays. Camonsertib shows 30-fold selectivity for ATR over mTOR (IC50=120 nM) and >2,000-fold selectivity over ATM, DNA-PK, and PI3Kα kinases. Camonsertib has potent antitumor activity.	price>
R-C-2727	GSK 0660 CAS：1014691-61-2	GSK 0660 is a selective PPARβ antagonist(IC50 values are 0.155,>10 and≥10µM at PPARβ,PPARα and PPARγ respectively).	price>
R-R-4427	Elimusertib hydrochloride	Elimusertib (BAY 1895344) hydrochloride is a potent, orally active and selective ATR inhibitor with an IC50 of 7 nM. Elimusertib hydrochloride has anti-tumor activity. Elimusertib hydrochloride can be used for the research of solid tumors and lymphomas.	price>
R-C-2728	Zardaverine CAS：101975-10-4	Zardaverine is a newly developed dual-selective PDE3/4 inhibitor with IC50 values of 0.5 uM and 0.8uM respectively.	price>
R-R-4428	Gartisertib CAS No.1613191-99-3	Gartisertib (VX-803)/CAS No.1613191-99-3 is an ATP-competitive, orally active, and selective ATR inhibitor, with a Ki of <150 pM. Gartisertib potently inhibits ATR-driven phosphorylated checkpoint kinase-1 (Chk1) phosphorylation with an IC50 of 8 nM. Antitumor activity.	price>
R-C-2729	PF-04457845 CAS:1020315-31-4	PF-04457845 is a highly efficacious and selective FAAH inhibitor with IC50 values is 7.2±0.63nM and 7.4±0.62nM for hFAAH and rFAAH,respectively.	price>
R-R-4429	Tuvusertib CAS No.1613200-51-3	Tuvusertib (M1774; ATR inhibitor 1)/CAS No.1613200-51-3 is a selective and orally active ATR inhibitor extracted from patent WO2015187451A1, compound I-l, with a Ki value below 1 μΜ.	price>
R-C-2730	MK-8245 CAS:1030612-90-8	MK-8245 is an liver-targeting inhibitor of stearoyl-CoA desaturase (SCD)with IC50 of 1 nM for human SCD1 and 3nM for both rat SCD1 and mouse SCD1,with anti-diabetic and anti-dyslipidemic efficacy.Phase 2.	price>
R-R-4430	Lartesertib CAS No.2495096-26-7	Lartesertib (M4076)/CAS No.2495096-26-7 is a potent inhibitor of serine/threonine protein kinase ATM (extracted from patent WO2022058351A1).	price>
R-C-2731	ABT-046 CAS:1031336-60-3	ABT-046 is a potent,selective,and orally efficacious acyl CoA:diacylglycerol acyltransferase 1(DGAT-1)inhibitor(IC50=8nM).	price>
R-R-4431	Ro 90-7501 CAS No.293762-45-5	Ro 90-7501/CAS No.293762-45-5 is an amyloid β42 (Aβ42) fibril assembly inhibitor that reduces Aβ42-induced cytotoxicity (EC50 of 2 μM). Ro 90-7501 inhibits ATM phosphorylation and DNA repair. RO 90-7501 selectively enhances toll-like receptor 3 (TLR3) and RIG-I-like receptor (RLR) ligand-induced IFN-β gene expression and antiviral response. Ro 90-7501 also inhibits protein phosphatase 5 (PP5) in a TPR-dependent manner. Ro 90-7501 has significant radiosensitizing effects on cervical cancer cells.	price>
R-C-2732	CS@Fe3O4 nanoparticles	The product is 30nm chitosan coated Fe3O4 magnetic nanoparticles with a large number of active amino groups on the surface and a saturation magnetization of 70-80.	price>
R-R-4432	(S)-Ceralasertib CAS No.1352226-87-9	(S)-Ceralasertib ((S)-AZD6738)/CAS No.1352226-87-9 is extracted from patent WO2011154737A1, Compound II, exhibits an IC50 of 2.578 nM. (S)-Ceralasertib is a potent and selective sulfoximine morpholinopyrimidine ATR inhibitor with excellent preclinical physicochemical and pharmacokinetic (PK) characteristics. (S)-Ceralasertib is developed improving aqueous solubility and eliminates CYP3A4 time-dependent inhibition.	price>
R-C-2733	MPPC	Pharmaceutical excipients,synthetic phospholipids(1-myristoyl-2-palmitoyl-sn-glycoro-3-phosphotidylcholine)were customized and synthesized in Ruixi BiotechCo.,Ltd.	price>
R-R-4433	AZ32 CAS No.2288709-96-4	AZ32/CAS No.2288709-96-4 is an orally bioavailable and blood-brain barrier-penetrating ATM inhibitor with an IC50 of <6.2 nM for ATM enzyme, and an IC50 of 0.31 μM for ATM in cell.	price>
R-C-2734	A939572 CAS：1032229-33-6	A939572 is a potent,and orally bioavailable stearoyl-CoA desaturase1(SCD1)inhibitor with IC50 values of <4nM and 37nM for mSCD1 and hSCD1,respectively.	price>
R-R-4434	NU6027 CAS No.220036-08-8	NU6027/CAS No.220036-08-8 is a potent and ATP-competitive inhibitor of both CDK1 and CDK2, with Kis of 2.5 µM and 1.3 µM, respectively. NU6027 is also a potent inhibitor of ATR and enhances hydroxyurea and cisplatin cytotoxicity in an ATR-dependent manner.	price>
R-C-2735	Telotristat CAS：1033805-28-5	Telotristat(LP-778902)is the acid form of Telotristat ethyl,and the active metabolite of LX1606(Telotristat etiprate),which is an orally bioavailable, small-molecule,tryptophan hydroxylase(TPH)inhibitor and serotonin synthesis inhibitor with potential antiserotonergic activity.	price>
R-R-4435	Elimusertib-d3	Elimusertib-d3 (BAY 1895344-d3) is the deuterium labeled Elimusertib (BAY 1895344). Elimusertib is a potent, orally active and selective ATR inhibitor and has anti-tumor activity.	price>

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