Home > Keywords >
| Catalog | name | Description | price |
|---|---|---|---|
| R-C-2805 | NKP608 CAS:177707-12-9 | NKP608 is a non-peptidic derivative of 4-aminopiperidine which acts as a selective,specific and potent antagonist at the neurokinin-1(NK-1)receptor both in vitro(IC50=2.6nM)and in vivo. | price> |
| R-R-4505 | Casein kinase 1o-IN-9 CAS No.854355-54-7 | Casein kinase 1δ-IN-9 (compound 737)/CAS No.854355-54-7 is a potent casein kinase 1δ (CK1δ/CK15) inhibitor. Casein kinase 1δ-IN-9 can be used for the research of neurodegenerative disorders such as Alzheimer disease. | price> |
| R-C-2806 | Sumanirole maleate CAS:179386-44-8 | Sumanirole maleate(U-95666E;PNU-95666E)is a highly selective D2 receptor full agonist with an ED50 of about 46nM.Sumanirole was developed for the treatment of Parkinson is disease and restless leg syndrome. | price> |
| R-R-4506 | Casein kinase 1o-IN-7 CAS No.764694-25-9 | Casein kinase 1δ-IN-7 (compound 497)/CAS No.764694-25-9 is a Casein kinase 1δ inhibitor. Casein kinase 1δ-IN-7 can be used in the study of neurodegenerative disorders such as Alzheimer disease. | price> |
| R-C-2807 | SDZ NKT 343 CAS:180046-99-5 | SDZ NKT 343 is a highly selective human tachykinin NK1 receptor antagonist that antagonizes SP-induced Ca2+ efflux in vitro and inhibits mechanical hyperalgesia in vivo. | price> |
| R-R-4507 | Casein kinase 1o-IN-3 CAS No.349438-77-3 | Casein kinase 1δ-IN-3 (Compound 23a)/CAS No.349438-77-3 is a casein kinase 1 delta (CK1d) inhibitor with a pIC50 of 6.5376 M. | price> |
| R-C-2808 | Almotriptan Malate CAS:181183-52-8 | Almotriptan malate(Axert)is a selective 5-hydroxytryptamine1B/1D(5-HT1B/1D) receptor agonist,used for the treatment of Migraine attacks in adults. | price> |
| R-R-4508 | Cyclophosphamide CAS No.50-18-0 | Cyclophosphamide/CAS No.50-18-0 is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant. | price> |
| R-C-2809 | LY 344864 CAS:186544-26-3 | LY344864 is a selective receptor agonist with an affinity of 6 nM(Ki)at the recently cloned 5-HT1F receptor. | price> |
| R-R-4509 | N-Nitroso-N-methylurea CAS No.684-93-5 | N-Nitroso-N-methylurea (NMU;MNU;NMH)/CAS No.684-93-5 is a potent carcinogen, mutagen and teratogenand. N-Nitroso-N-methylurea is a direct-acting alkylating agent that interacts with DNA. N-Nitroso-N-methylurea targets multiple animal organs to cause various cancer and/or degenerative disease. N-Nitroso-N-methylurea is also a precursor in the synthesis of diazomethane. | price> |
| R-C-2810 | L 760735 CAS:188923-01-5 | High affinity NK1 receptor antagonist(IC50=0.19nM at human NK1 receptors). Selective(>300-fold)over h-NK2 and h-NK3 receptors.Exhibits anxiolytic and antidepressant-like effects. | price> |
| R-R-4510 | Azoxymethane CAS No.25843-45-2 | Azoxymethane/AOM/CAS No.25843-45-2 is a colon carcinogen which leads to the formation of DNA adducts. | price> |
| R-C-2811 | NGB 2904 CAS:189060-98-8 | NGB 2904 is an orally active and selective dopamine(DA)D3 receptor antagonist.NGB 2904 can be used for the research of cocaine addiction. | price> |
| R-R-4511 | Phosphoramide mustard cyclohexanamine CAS No.1566-15-0 | Phosphoramide mustard cyclohexanamine/CAS No.1566-15-0 is a biologically active metabolite of Cyclophosphamide (HY-17420), with anticancer activitiy. Phosphoramide mustard cyclohexanamine induces DNA damage. | price> |
| R-C-2812 | Firocoxib CAS:189954-96-9 | Firocoxib is a non-steroidal anti-inflammatory drug of the COX-2 inhibitor class,currently approved for use in dogs and horses. | price> |
| R-R-4512 | Calicheamicin CAS No.108212-75-5 | Calicheamicin/CAS No.108212-75-5, an antitumor antibiotic, is a cytotoxic agent that causes double-strand DNA breaks. Calicheamicin is a DNA synthesis inhibitor. Calicheamicin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | price> |
| R-C-2813 | Bepotastine Besilate CAS:190786-44-8 | Bepotastine besilate is a selective and orally active second-generation histamine H1 receptor antagonist.Bepotastine besilate has the potential for allergic rhinitis,allergic conjunctivitis and urticaria/pruritus research. | price> |
| R-R-4513 | Lurbinectedin CAS No.497871-47-3 | Lurbinectedin (PM01183)/CAS No.497871-47-3 is a DNA minor groove covalent binder with potent anti-tumour activity; inhibits RMG1 and RMG2 cell growth with IC50 values of 1.25 and 1.16 nM, respectively. | price> |
| R-C-2814 | LY 379268 CAS:191471-52-0 | LY379268 is a potent,selective and brain-penetrant mGlu2/3R agonist with EC50 values of 2.69nM(mGlu2)and 4.48nM(mGlu3).LY379268 has no activity on human mGlu 1a,4a,5a or 7a receptors.LY379268 has antioxidant and neuroprotective effects. | price> |
| R-R-4514 | SG3199 CAS No.1595275-71-0 | SG3199/CAS No.1595275-71-0 is a cytotoxic DNA minor groove interstrand crosslinking pyrrolobenzodiazepine (PBD) dimer. SG3199 is the released warhead component of the ADC payload Tesirine (SG3249). | price> |

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