Xi'an ruixi Biological Technology Co

Home > Keywords >

Catalog	name	Description	price
R-C-3114	GNE-6640 CAS：2009273-67-8	GNE-6640 is a selective and non-covalent inhibitor of ubiquitin epecific peptidase 7 (USP7), with IC50 values of 0.75 μM,0.43 μM,20.3μM and 0.23μM for full length USP7, USP7 catalytic domain, full length USP43 and Ub-MDM2,respectively.	price>
R-R-4784	EFdA-TP tetrasodium CAS No.2883783-00-2	EFdA-TP tetrasodium/CAS No.2883783-00-2 is a potent nucleoside reverse transcriptase (RT) inhibitor. EFdA-TP tetrasodium inhibits RT-catalyzed DNA synthesis as an effective immediate or delayed chain terminator (ICT or DCT). EFdA-TP tetrasodium inhibits HIV-1 RT with multiple mechanisms. EFdA-TP (tetrasodium) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.	price>
R-C-3115	DUBs-IN-2 CAS：924296-19-5	DUBs-IN-2 is a potent deubiquitinase enzyme inhibitor with IC50s of 7.2uM/0.93uM for USP7/USP8 respectively.	price>
R-R-4785	8-NH2-ATP tetrasodium CAS No.35892-97-8	8-NH2-ATP tetrasodium/CAS No.35892-97-8, an inactive form of ATP, is produced by 8-NH2-Ado. 8-NH2-Ado tetrasodium induces apoptosis-related cleavage of poly (ADP-ribose) polymerase.	price>
R-C-3116	HBX 41108 CAS：924296-39-9	HBX 41108 is an inhibitor of ubiquitin-specific protease (USP)7 activity(IC50=424nM).	price>
R-R-4786	RNase L-IN-1 trihydrochloride	RNase L-IN-1 (compound 17a) trihydrochloride is an inhibitor of RNase L or ribonuclease L. RNase L degrades RNA to prevent viral replication and mediates innate immune responses and inflammation.	price>
R-C-3117	GNE-490 CAS：1033739-92-2	GNE-490 is a highly selective pan-PI3K inhibitor that demonstrates selectivity over mTOR.	price>
R-R-4787	Enoxacin-d8 hydrochloride	Enoxacin-d8 (hydrochloride) is deuterium labeled Enoxacin. Enoxacin (AT 2266), a fluoroquinolone, interferes with DNA replication and inhibits bacterial DNA gyrase (IC50=126 µg/ml) and topoisomerase IV (IC50=26.5 µg/ml). Enoxacin is a miRNA processing activator and enhances siRNA-mediated mRNA degradation and promotes the biogenesis of endogenous miRNAs. Enoxacin has potent activities against gram-positive and -negative bacteria. Enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing.	price>
R-C-3118	GNE-9605 CAS：1536200-31-3	GNE-9605 is a highly potent and selective leucine-rich repeat kinase 2 (LRRK2)inhibitor with Ki and IC50 of 2 nM and 19 nM,respectively.	price>
R-R-4788	hDHODH-IN-3 CAS No.1644156-80-8	hDHODH-IN-3 (compound 21d)/CAS No.1644156-80-8 is a human dihydroorotate dehydrogenase (HsDHODH) inhibitor, inhibits measles virus replication with a pMIC50 value of 8.6.	price>
R-C-3119	Vialinin A CAS：858134-23-3	Vialinin A is a terphenyl compound originally isolated from the fungi T. terrestris and T.vialis.	price>
R-R-4789	Thymidine-15N2	Thymidine-15N2 is the 15N labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication.	price>
R-C-3120	MSC1094308 CAS:2219320-08-6	MSC1094308 is a reversible and allosteric inhibitor of the type II AAA ATPase human ubiquitin-directed unfoldase(VCP)/p97 and the type I AAA ATPase VPS4B,with IC50 values of 0.71μM and 7.2μM for VPS4B and p97,respectively.	price>
R-R-4790	Mitonafide CAS No.54824-17-8	Mitonafide (NSC 300288)/CAS No.54824-17-8 is a cytostatic agent. Mitonafide binds to double-stranded DNA through intercalation, and inhibits DNA and RNA synthesis. Mitonafide is an antitumor agent that can be used in the research of cancers, such as non-small cell lung cancer (NSCLC), leukemia.	price>
R-C-3121	NMS-859 CAS:1449236-96-7	NMS-859 is a potent,covalent VCP(p97)inhibitor,with IC50s of 0.37 and 0.36μM for wild-type VCP in the presence of 60μM and 1 mM ATP in cells,respectively.	price>
R-R-4791	Werner syndrome RecQ helicase-IN-4 CAS No.2869954-53-8	Werner syndrome RecQ helicase-IN-4/CAS No.2869954-53-8 is a potent and orally active werner syndrome recQ helicase (WRN) inhibitor with an IC50 value of 0.06 µM. Werner syndrome RecQ helicase-IN-4 shows antiproliferative activity. Werner syndrome RecQ helicase-IN-4 shows anticancer activity.	price>
R-C-3122	ML241 CAS:1346528-06-0	ML241 is a potent and selective inhibitors of p97 ATPase. ML241 inhibit p97 ATPase with IC(50) values of 100 nM. ML241 inhibits degradation of a p97-dependent but not a p97-independent proteasome substrate in a dual-reporter cell line.	price>
R-R-4792	Cy5-dATP	Cy5-dATP is a Cy5 (HY-D0821)-labeled dATP (HY-136648). Cy5-dATP can be incorporated into a DNA primer.	price>
R-C-3123	SR-2211 CAS:1359164-11-6	SR-2211 selectively binds RORr(Ki=105nM),acting as an inverse agonist of constitutive in vitro RORr activity (IC50=320nM).	price>
R-R-4793	Enocitabine CAS No.55726-47-1	Enocitabine/CAS No.55726-47-1 is a nucleoside analog, and is a potent DNA replication inhibitor, and a DNA chain terminator. Enocitabine inhibits the replication of human cytomegalovirus. Enocitabine has antileukemic and antiviral activities.	price>

688689690691692693 694695696697698