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Catalog	name	Description	price
R-R-4853	Gemcitabine elaidate hydrochloride CAS No.2918768-08-6	Gemcitabine elaidate (CP-4126) hydrochloride/CAS No.2918768-08-6 is lipophilic pro-agent of Gemcitabine. Gemcitabine elaidate hydrochloride is converted to Gemcitabine by esterases in order to be phosphorylated. Gemcitabine elaidate hydrochloride exhibits anti-tumor activity.	price>
R-C-3184	PPQ-102 CAS:931706-15-9	PPQ-102(CFTR Inhibitor IV)is a potent inhibitor of CFTR.PPQ-102 can completely inhibit CFTR chloride current with IC50 of ~90nM.	price>
R-R-4854	Rabacfosadine CAS No.859209-74-8	Rabacfosadine (GS-9219)/CAS No.859209-74-8, a novel proagent of the nucleotide analogue PMEG, is designed as a cytotoxic agent that preferentially targets lymphoid cells.	price>
R-C-3185	KM 11060 CAS:774549-97-2	KM 11060 is a small molecule that corrects the processing of cystic fibrosis transmembrane conductance regulator (CFTR) proteins bearing the F508 deletion (F508del) mutation carried by 90% of cystic fibrosis patients.KM 11060 corrects F508del-CFTR trafficking, increasing the amount of functional CFTR at the plasma membrane (~75%) and Inhibits PDE5 activity.	price>
R-R-4855	5-(Hydroxymethyl)cytidine CAS No.19235-17-7	5-(Hydroxymethyl)cytidine/CAS No.19235-17-7 is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.	price>
R-C-3186	GLPG2451 CAS:2055015-61-5	GLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator, which effectively potentiates low temperature rescued F508del CFTR with an EC50 of 11.1 nM.	price>
R-R-4856	Valopicitabine dihydrochloride CAS No.640725-71-9	Valopicitabine (NM283) dihydrochloride/CAS No.640725-71-9 is a nucleoside analog and the orally bioavailable proagent of the potent anti-HCV agent 2-C-methylcytidine (NM107). NM107competitively inhibits NS5B polymerase, causing chain termination.	price>
R-C-3187	Caldaret (MCC-135) CAS:133804-44-1	Caldaret is an intracellular Ca2+ handling modulator that acts through reverse mode Na+/Ca2+ exchanger inhibition.	price>
R-R-4857	Adenosine-d2 CAS No.82741-17-1	Adenosine-d2/CAS No.82741-17-1 is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physio.	price>
R-C-3188	TTA-Q6 CAS:910484-28-5	TTA-Q6 is a selective T-type Ca2+ channel antagonist, which can be used in the research of neurological disease.	price>
R-R-4858	3-O-Methylguanosine CAS No.10300-27-3	3-O-Methylguanosine/CAS No.10300-27-3 is a methylated nucleoside analogs and a RNA chain terminator. 3-O-methylguanosine can inhibit early virus-specific RNA synthesis.	price>
R-C-3189	GV-58 CAS:1402821-41-3	GV-58 is a potent, selective N- and P/Q-type Ca2+ channels agonist with EC50 of 7.21/8.81 uM for N-type/P-Q-type Ca2+ channel; 20-fold less potent CDK inhibitor activity.	price>
R-R-4859	3-Deoxyuridine-5-triphosphate trisodium	3-Deoxyuridine-5-triphosphate trisodium (3-dUTP trisodium) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3-Deoxyuridine-5-triphosphate trisodium strongly and competitively inhibits the incorporations of UTP into RNA with a Ki value of 2.0 μM.	price>
R-C-3190	Isradipine (Dynacirc) CAS:75695-93-1	Isradipine(PN 200-110)is a potent and selective L-type voltage-gated calcium channel blocker,used to treat high blood pressure.	price>
R-R-4860	2-O,4-C-Methylenecytidine CAS No.206055-69-8	2-O,4-C-Methylenecytidine (LNA-C(Bz))/CAS No.206055-69-8 is a bicyclic nucleoside analogue with fixed N-type conformation. 2-O,4-C-Methylenecytidine can be used to synthesize oligonucleotides. 2-O,4-C-Methylenecytidine forms duplexes with complementary DNA and RNA strands.	price>
R-C-3191	Dantrolene CAS: 7261-97-4	Dantrolene sodium is a muscle relaxant that acts by abolishing excitation-contraction coupling in muscle cells, probably by action on the ryanodine receptor.	price>
R-R-4861	Adenosine-13C10,15N5 CAS No.202406-75-5	Adenosine-13C10,15N5/CAS No.202406-75-5 is the 13C and 15N labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation.	price>
R-C-3192	Atagabalin CAS:223445-75-8	Atagabalin is related to gabapentin, which similarly binds to the α2δ calcium channels (1 and 2).	price>
R-R-4862	N-6-Methyl-2-deoxyadenosine CAS No.2002-35-9	N-6-Methyl-2-deoxyadenosine/CAS No.2002-35-9 is an adenine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.	price>
R-C-3193	NNC 55-0396 CAS:357400-13-6	NNC 55-0396, Mibefradil derivative, is a highly selective T-type calcium channel blocker; displays IC50 values of 6.8 and>100μM for inhibition of Cav3.1 T-type channels and HVA currents respectively in INS-1 cells.Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>

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