Product fluorescent-dyes-No-ROS-Rox-derivatives

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Catalog	name	Description	price
R-XASYS-00466	ON1231320,cas:1312471-39-8	ON1231320(C22H15F2N5O3S,467.4) is a highly specific polo like kinase 2 (PLK2) inhibitor with an IC50 of 0.31 µM. ON1231320 blocks tumor cell cycle progression in the G2/M phase in mitosis, causing apoptotic cell death. ON1231320, an arylsulfonyl pyrido-pyrimidinone, has antitumor activity.	price>
R-XASYS-00467	TY-51469,cas:603987-59-3	TY-51469(C20H15FN2O6S4,526.6) is a chymase inhibitor with IC50s for simian and human chymases of 0.4 and 7.0 nM, respectively.	price>
R-XASYS-00468	GW-406381,cas:221148-46-5	GW 406381(C21H19N3O3S,393.5) is a non-steroidal anti-inflammatory drug (NSAID) and COX-2 inhibitor (IC50 = 3 nM).It is selective for COX-2 over COX-1 (IC50 = >84.2 µM). GW 406381 (5 mg/kg) reverses chronic construction injury-induced decreases in paw withdrawal thresholds in a rat model of neuropathic pain.	price>
R-XASYS-00469	NSC639828,cas:134742-26-0	NSC639828(C18H13BrClN5O3,462.68) is a potent inhibitor of DNA polymeraseαwith an IC50 of 70μM. NSC639828 has high antitumor activity. NSC639828 has the potential for researching cancer disease.	price>
R-XASYS-00470	Methyl citrate,cas:26163-61-1	Methyl citrate(C7H10O7,206.15) is a Monoamine oxidase B (MAO-B) inhibitor (IC50=0.23 mM).	price>
R-XASYS-00471	2-methoxy Estrone,cas:362-08-3	2-methoxy Estrone(C19H24O3,300.4) is an active metabolite of the endogenous estrogen estrone.It is formed from estrone by catechol-O-methyltransferase (COMT). 2-methoxy Estrone inhibits the proliferation of isolated bovine brain-derived capillary endothelial cells (IC50 = 11.5 µM).	price>
R-XASYS-00472	2-PMPA,cas:173039-10-6	PMPA (NAALADase inhibitor)(C6H11O7P,226.12) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM	price>
R-XASYS-00473	Lu AF21934,cas:1445605-23-1	Lu AF21934(C14H16Cl2N2O2,315.2) is a positive allosteric modulator (PAM) of metabotropic glutamate receptor 4 (mGluR4; EC50 = 500 nM for the human receptor in a FLIPR assay).It is selective for mGluR4 over mGluR6 (EC50 = 7μM) and a panel of 73 CNS ion channels, G protein-coupled receptors (GPCRs), and enzymes at 10μM.	price>
R-XASYS-00474	MAC13772,cas:4871-40-3	MAC13772(C8H9N3O3S,227.24) is a potent inhibitor of the enzyme BioA (IC50=250 nM), the antepenultimate step in biotin biosynthesis. MAC13772 is a novel antibacterial compound.	price>
R-XASYS-00475	Febuxostat impurity 7,cas:1350352-70-3	Febuxostat impurity 7(C16H18N2O4S,334.39) is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM.	price>

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