Product apis-apoptosis

Home > products > apis> apoptosis

Catalog	name	Description	price
R-R-1867	ROC-325 CAS No.1859141-26-6	ROC-325/CAS No.1859141-26-6 is a potent and orally active autophagy inhibitor with a strong anticancer activity. ROC-325 induces the deacidification of lysosomes, accumulation of autophagosomes, and disrupted autophagic flux. ROC-325 also induces renal cell carcinoma apoptosis.	price>
R-R-1868	Bioymifi CAS No.1420071-30-2	Bioymifi (DR5 Activator)/CAS No.1420071-30-2, a potent TRAIL receptor DR5 activator, binds to the extracellular domain (ECD) of DR5 with a Kd of 1.2 μM. Bioymifi can act as a single agent to induce DR5 clustering and aggregation, leading to apoptosis.	price>
R-R-1869	Milademetan tosylate hydrate CAS No.2095625-97-9	Milademetan (DS-3032) tosylate hydrate/CAS No.2095625-97-9 is a specific and orally active MDM2 inhibitor for the research of acute myeloid leukemia (AML) or solid tumors. Milademetan (DS-3032) tosylate hydrate induces G1 cell cycle arrest, senescence and apoptosis.	price>
R-R-1870	Oxythiamine CAS No.136-16-3	Oxythiamine (Hydroxythiamin)/CAS No.136-16-3, an analogue of anti-metabolite, can suppress the non-oxidative synthesis of ribose and induce cell apoptosis. Oxythiamine is a thiamine antagonist and inhibits transketolase (TK). Oxythiamine inhibits cancer cell apoptosis and inhibits cell proliferation.	price>
R-R-1871	MARK4 inhibitor 1 CAS No.2271081-58-2	MARK4 inhibitor 1/CAS No.2271081-58-2 is a potent and selective microtubule affinity-regulating kinase 4 (MARK4) inhibitor, with an IC50 of 1.54 μM. MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis.	price>
R-R-1872	RKI-1447 dihydrochloride CAS No.1782109-09-4	RKI 1447 dihydrochloride/CAS No.1782109-09-4 is a potent and selective ROCK inhibitor with IC50s of 14.5 and 6.2 nM for ROCK1 and ROCK2, respectively. RKI 1447 dihydrochloride suppresses colorectal carcinoma cell growth and promotes apoptosis.	price>
R-R-1873	Glycochenodeoxycholic acid-d4 CAS No.1201918-16-2	Glycochenodeoxycholic acid-d4/CAS No.1201918-16-2 is the deuterium labeled Glycochenodeoxycholic acid. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) induces hepatocyte apoptosis.	price>
R-R-1874	Tubulin inhibitor 1 CAS No.2237054-53-2	Tubulin inhibitor 1/CAS No.2237054-53-2 is a tubulin inhibitor, inhibits tubulin polymerization. Tubulin inhibitor 1 shows potent anti-tumor activity, casues cellular mitotic arrest in the G2/M phase, and induces cellular apoptosis.	price>
R-R-1875	Isoalantolactone CAS No.470-17-7	Isoalantolactone/CAS No.470-17-7 is an apoptosis inducer, which also acts as an alkylating agent.	price>
R-R-1876	Norartocarpetin CAS No.520-30-9	Norartocarpetin/CAS No.520-30-9 is a tyrosinase inhibitor. Norartocarpetin has strong tyrosinase inhibitory activity with an IC50 value of 0.47 μM. Norartocarpetin as an antibrowning agent can be used for the research of food systems. Norartocarpetin also has a significant anticancer activity in lung carcinoma cells (NCI-H460) with an IC50 value of 22 μM. Norartocarpetin has antiproliferative effects are mediated via targeting Ras/Raf/MAPK signalling pathway, mitochondrial mediated apoptosis, S-phase cell cycle arrest and suppression of cell migration and invasion in human lung carcinoma cells.	price>

...