Product apis-dna-damage-dna-repa

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Catalog	name	Description	price
R-R-4750	SCR7 CAS No.1533426-72-0	SCR7/CAS No.1533426-72-0 is an unstable form that can be autocyclized into a stable form SCR7 pyrazine. SCR7 pyrazine is a DNA ligase IV inhibitor that blocks nonhomologous end-joining (NHEJ) in a ligase IV-dependent manner. SCR7 pyrazine is also a CRISPR/Cas9 enhancer which increases the efficiency of Cas9-mediated homology-directed repair (HDR). SCR7 pyrazine induces cell apoptosis and has anticancer activity.	price>
R-R-4751	Deoxycytidine triphosphate CAS No.2056-98-6	Deoxycytidine triphosphate (dCTP)/CAS No.2056-98-6 is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.	price>
R-R-4752	Novobiocin CAS No.303-81-1	Novobiocin (Albamycin)/CAS No.303-81-1 is a potent and orally active antibiotic. Novobiocin also is a DNA gyrase inhibitor and a heat shock protein 90 (Hsp90) antagonist. Novobiocin has the potential for the research of highly beta-lactam-resistant pneumococcal infections. Novobiocin shows anti-orthopoxvirus activity.The free form of the compound is prone to instability, it is advisable to consider the stable salt form (Novobiocin sodium) that retains the same biological activity.	price>
R-R-4753	Crisnatol CAS No.96389-68-3	Crisnatol (BWA770U)/CAS No.96389-68-3 is an orally active and anticancer agent, and a member of the arylmethylaminopropanediol class of DNA intercalators. Crisnatol shows in vitro cytotoxicity against human breast cancer cells, but not normal human skin fibroblasts.	price>
R-R-4754	Herboxidiene CAS No.142861-00-5	Herboxidiene (GEX1A)/CAS No.142861-00-5 is a potent phytotoxic polyketide from Streptomyces sp. A7847 with a diverse range of activities, including herbicidal, anti-cholesterol, anti-tumor effects. Herboxidiene inhibits the pre-mRNA splicing process by binding to spliceosome-associated protein (SAP) 155, a subunit of SF3b, in the splicesome.	price>
R-R-4755	5-PA-dUTP CAS No.179101-49-6	5-PA-dUTP (5-Propargylamino-dUTP)/CAS No.179101-49-6 is a C5-modified nucleotide and can be incorporated into DNA nanoparticles (DNPs) for photosensitizer delivery. 5-PA-dUTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.	price>
R-R-4756	NSC 80467 CAS No.101982-51-8	NSC 80467/CAS No.101982-51-8, a DNA damaging agent, selectively inhibits survivin. NSC 80467 preferentially inhibits DNA synthesis and results in induction of γH2AX and pKAP1, two markers of DNA damage.	price>
R-R-4757	MC-VC-PAB-Cyclohexanediamine-Thailanstatin A CAS No.1609108-96-4	MC-VC-PAB-Cyclohexanediamine-Thailanstatin A/CAS No.1609108-96-4 is a Spliceostatin (HY-16466) analog, and a drug-linker conjugates for ADC, consisting of ADC Cytotoxin Thailanstatin A (HY-129589) and cleavable ADC linker (MC-vc-PAB). MC-VC-PAB-Cyclohexanediamine-Thailanstatin A can be used for ADC synthesis.	price>
R-R-4758	FAICAR CAS No.13018-54-7	FAICAR (5-Formamidoimidazole-4-carboxamide ribotide)/CAS No.13018-54-7 is a purine nucleotide.	price>
R-R-4759	Cytarabine-d2 CAS No.40632-26-6	Cytarabine-d2/CAS No.40632-26-6 is the deuterium labeled Cytarabine. Cytarabine, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. Cytarabine has antiviral effects against HSV.	price>

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