Product apis-gpcr-g-protein

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Catalog	name	Description	price
R-R-3535	Doxofylline CAS No.69975-86-6	Doxofylline/CAS No.69975-86-6 is an orally active PDE IV inhibitor and A1AR antagonist. Doxofylline reduces inflammation in epithelial cells via inhibiting mitochondrial ROS production and amelioration of multiple cellular pathways (NLRP3-TXNIP inflammasome activation). Doxophylline can be used in studies of asthma, chronic obstructive pulmonary disease, and bronchospasm.	price>
R-R-3536	GS-6201 CAS No.752222-83-6	GS-6201 (CVT-6883)/CAS No.752222-83-6 is a selective adenosine A2B receptor antagonist. GS-6201 displays high affinity and selectivity for the human adenosine A2B receptors (Ki=22 nM). GS-6201 reduces caspase-1 activity in the heart, and attenuates cardiac remodeling after acute myocardial infarction (AMI) in the mouse. GS-62013 attenuates the airway reactivity induced by NECA, AMP, or allergen in sensitized mice.	price>
R-R-3537	LAS101057 CAS No.925676-48-8	LAS101057/CAS No.925676-48-8 is a potent, selective, and orally efficacious A2B receptor antagonist.	price>
R-R-3538	Tozadenant CAS No.870070-55-6	Tozadenant/CAS No.870070-55-6 is an adenosine A2A receptor antagonist, with Ki of 11.5 nM on human A2A and 6 nM on rhesus A2A.	price>
R-R-3539	N6-Ethyladenosine CAS No.14357-08-5	N6-Ethyladenosine/CAS No.14357-08-5 is an adenosine derivative, acts as a Adenosine receptor agonist, with Kis of 4.9 and 4.7 nM for hA1AR and hA3AR, respectively.	price>
R-R-3540	N6-(2-Phenylethyl)adenosine CAS No.20125-39-7	N6-(2-Phenylethyl)adenosine (N6-Phenethyladenosine)/CAS No.20125-39-7, an adenosine derivative, is a potent adenosine receptors (AR) agonist with Ki values of 11.8 nM, 30.1 nM, 0.63 nM for rat A1AR, human A1AR and hA3AR, respectively.	price>
R-R-3541	DPTN dihydrochloride CAS No.325767-87-1	DPTN/CAS No.325767-87-1 is a potent and selective human, mouse, and rat A3AR antagonist with Ki values of 1.65, 9.61, and 8.53 nM, respectively.	price>
R-R-3542	M1069	M1069 is a selective and orall active, dual A2A/A2B adenosine receptor antagonist with a selectivity of >100 fold against the A1 and A3 receptors. M1069 counteracts immune-suppressive mechanisms of adenosine, and exhibits anti-tumor activity.	price>
R-R-3543	MIPS521 CAS No.1146188-19-3	MIPS521/CAS No.1146188-19-3 is a positive allosteric modulator of adenosine A1 receptor (A1AR). MIPS521 also has a lower A1R allosteric affinity (pKB=4.95; KB=11 μM). MIPS521 exhibits pain-relieving effects in vivo through modulation of the increased levels of endogenous adenosine.	price>
R-R-3544	N-[(4-Aminophenyl)methyl]adenosine CAS No.95523-13-0	N-[(4-Aminophenyl)methyl]adenosine/CAS No.95523-13-0 is a adenosine receptor inhibitor, with Ki of 29 nM for Rat ecto-5-Nucleotidase.	price>

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